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Aliases for C14orf37 Gene

Aliases for C14orf37 Gene

  • Chromosome 14 Open Reading Frame 37 2 3
  • C14_5376 3

External Ids for C14orf37 Gene

Previous GeneCards Identifiers for C14orf37 Gene

  • GC14M052267
  • GC14M056460
  • GC14U900322
  • GC14M057540
  • GC14M058470
  • GC14M038636

Summaries for C14orf37 Gene

GeneCards Summary for C14orf37 Gene

C14orf37 (Chromosome 14 Open Reading Frame 37) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf37 Gene

Genomics for C14orf37 Gene

Regulatory Elements for C14orf37 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C14orf37 Gene

57,993,531 bp from pter
58,298,139 bp from pter
304,609 bases
Minus strand

Genomic View for C14orf37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for C14orf37 Gene

Proteins for C14orf37 Gene

  • Protein details for C14orf37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C14orf37
    Protein Accession:
    Secondary Accessions:
    • A8K8Z8
    • Q6P5Q1
    • Q86TY1

    Protein attributes for C14orf37 Gene

    774 amino acids
    Molecular mass:
    84173 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C14orf37 Gene


neXtProt entry for C14orf37 Gene

Proteomics data for C14orf37 Gene at MOPED

Post-translational modifications for C14orf37 Gene

  • Glycosylation at Asn 57, Thr 96, Ser 135, Asn 189, and Ser 389
  • Modification sites at PhosphoSitePlus

Other Protein References for C14orf37 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf37 Gene

Domains & Families for C14orf37 Gene

Protein Domains for C14orf37 Gene


Suggested Antigen Peptide Sequences for C14orf37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf37: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C14orf37 Gene

Function for C14orf37 Gene

Phenotypes for C14orf37 Gene

GenomeRNAi human phenotypes for C14orf37:
genes like me logo Genes that share phenotypes with C14orf37: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf37

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf37 Gene

Localization for C14orf37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf37 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for C14orf37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C14orf37: view

No data available for Subcellular locations from COMPARTMENTS for C14orf37 Gene

Pathways & Interactions for C14orf37 Gene

SuperPathways for C14orf37 Gene

No Data Available

Interacting Proteins for C14orf37 Gene

Gene Ontology (GO) - Biological Process for C14orf37 Gene


No data available for Pathways by source and SIGNOR curated interactions for C14orf37 Gene

Drugs & Compounds for C14orf37 Gene

No Compound Related Data Available

Transcripts for C14orf37 Gene

mRNA/cDNA for C14orf37 Gene

(3) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C14orf37 Gene

Chromosome 14 open reading frame 37:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf37

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf37 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP2: -

Relevant External Links for C14orf37 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C14orf37 Gene

mRNA expression in normal human tissues for C14orf37 Gene

Protein differential expression in normal tissues from HIPED for C14orf37 Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C14orf37 Gene

SOURCE GeneReport for Unigene cluster for C14orf37 Gene Hs.535420

genes like me logo Genes that share expression patterns with C14orf37: view

Protein tissue co-expression partners for C14orf37 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C14orf37 Gene

Orthologs for C14orf37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf37 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C10H14orf37 35
  • 82.14 (n)
  • 73.74 (a)
C14orf37 36
  • 73 (a)
(Canis familiaris)
Mammalia C8H14orf37 35
  • 83.68 (n)
  • 75.45 (a)
C14orf37 36
  • 69 (a)
(Mus musculus)
Mammalia 3632451O06Rik 35
  • 72.38 (n)
  • 57.5 (a)
3632451O06Rik 16
3632451O06Rik 36
  • 55 (a)
(Pan troglodytes)
Mammalia C14H14orf37 35
  • 99.01 (n)
  • 98.32 (a)
C14ORF37 36
  • 94 (a)
(Rattus norvegicus)
Mammalia RGD1310110 35
  • 71.52 (n)
  • 57.94 (a)
(Monodelphis domestica)
Mammalia C14orf37 36
  • 51 (a)
(Ornithorhynchus anatinus)
Mammalia C14orf37 36
  • 36 (a)
(Gallus gallus)
Aves C5H14ORF37 35
  • 54.11 (n)
  • 43.42 (a)
C14orf37 36
  • 37 (a)
(Anolis carolinensis)
Reptilia C14orf37 36
  • 88 (a)
Species with no ortholog for C14orf37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf37 Gene

Gene Tree for C14orf37 (if available)
Gene Tree for C14orf37 (if available)

Paralogs for C14orf37 Gene

No data available for Paralogs for C14orf37 Gene

Variants for C14orf37 Gene

Sequence variations from dbSNP and Humsavar for C14orf37 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs111555 -- 58,054,045(+) ctgtg(A/G)aaagt intron-variant
rs115718 -- 58,059,463(-) TTTAA(G/T)TAGAG intron-variant
rs178473 -- 58,050,568(+) CTGAA(C/G)GTAAG intron-variant
rs178474 -- 58,051,134(+) ATCTA(C/G)TATTT intron-variant
rs178475 -- 58,052,417(+) TCATG(C/G)GAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf37 Gene

Variant ID Type Subtype PubMed ID
esv34185 CNV Loss 18971310
nsv507752 CNV Insertion 20534489
nsv826959 CNV Loss 20364138
esv2319201 CNV Deletion 18987734
esv2677940 CNV Deletion 23128226
esv2657771 CNV Deletion 23128226

Variation tolerance for C14orf37 Gene

Residual Variation Intolerance Score: 89.19% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 15.96; 97.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf37 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf37 Gene

Disorders for C14orf37 Gene

Relevant External Links for C14orf37

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C14orf37: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf37 Gene

Publications for C14orf37 Gene

  1. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. (PMID: 24925725) Chung S.A. … Langefeld C.D. (J. Am. Soc. Nephrol. 2014) 67
  2. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 67
  3. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PMID: 20235792) Uhl G.R. … MunafA^ M.R. (Pharmacogenomics 2010) 67
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for C14orf37 Gene

Sources for C14orf37 Gene

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