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Aliases for C14orf37 Gene

Aliases for C14orf37 Gene

  • Chromosome 14 Open Reading Frame 37 2 3
  • Uncharacterized Protein C14orf37 3
  • C14_5376 3

External Ids for C14orf37 Gene

Summaries for C14orf37 Gene

GeneCards Summary for C14orf37 Gene

C14orf37 (Chromosome 14 Open Reading Frame 37) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf37 Gene

Genomics for C14orf37 Gene

Genomic Location for C14orf37 Gene

Start:
57,999,735 bp from pter
End:
58,298,139 bp from pter
Size:
298,405 bases
Orientation:
Minus strand

Genomic View for C14orf37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf37 Gene

Regulatory Elements for C14orf37 Gene

Proteins for C14orf37 Gene

  • Protein details for C14orf37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86TY3-CN037_HUMAN
    Recommended name:
    Uncharacterized protein C14orf37
    Protein Accession:
    Q86TY3
    Secondary Accessions:
    • A8K8Z8
    • Q6P5Q1
    • Q86TY1

    Protein attributes for C14orf37 Gene

    Size:
    774 amino acids
    Molecular mass:
    84173 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C14orf37 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C14orf37 Gene

Proteomics data for C14orf37 Gene at MOPED

Post-translational modifications for C14orf37 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn57, Ser91, Thr96, Ser135, Ser138, Asn189, and Ser389

Other Protein References for C14orf37 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf37 Gene

Domains for C14orf37 Gene

Protein Domains for C14orf37 Gene

ProtoNet:
genes like me logo Genes that share domains with C14orf37: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C14orf37 Gene

Function for C14orf37 Gene

miRNA for C14orf37 Gene

miRTarBase miRNAs that target C14orf37

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C14orf37 Gene

Localization for C14orf37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf37 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf37 Gene COMPARTMENTS Subcellular localization image for C14orf37 gene
Compartment Confidence
extracellular 2
plasma membrane 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for C14orf37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C14orf37: view

Pathways for C14orf37 Gene

SuperPathways for C14orf37 Gene

No Data Available

Interacting Proteins for C14orf37 Gene

Gene Ontology (GO) - Biological Process for C14orf37 Gene

None

No data available for Pathways by source for C14orf37 Gene

Transcripts for C14orf37 Gene

mRNA/cDNA for C14orf37 Gene

(3) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C14orf37 Gene

Chromosome 14 open reading frame 37:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf37 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1:
SP2: -
SP3:

Relevant External Links for C14orf37 Gene

GeneLoc Exon Structure for
C14orf37
ECgene alternative splicing isoforms for
C14orf37

Expression for C14orf37 Gene

mRNA expression in normal human tissues for C14orf37 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C14orf37 Gene

SOURCE GeneReport for Unigene cluster for C14orf37 Gene Hs.535420

genes like me logo Genes that share expressions with C14orf37: view

Orthologs for C14orf37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf37 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf37 36
  • 99.01 (n)
  • 98.32 (a)
C14ORF37 37
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C10H14orf37 36
  • 82.14 (n)
  • 73.74 (a)
C14orf37 37
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C14orf37 37
  • 69 (a)
OneToOne
C8H14orf37 36
  • 83.68 (n)
  • 75.45 (a)
mouse
(Mus musculus)
Mammalia 3632451O06Rik 36
  • 72.38 (n)
  • 57.5 (a)
3632451O06Rik 16
3632451O06Rik 37
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C14orf37 37
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf37 37
  • 36 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1310110 36
  • 71.52 (n)
  • 57.94 (a)
chicken
(Gallus gallus)
Aves C14orf37 37
  • 37 (a)
OneToOne
C5H14ORF37 36
  • 54.11 (n)
  • 43.42 (a)
lizard
(Anolis carolinensis)
Reptilia C14orf37 37
  • 88 (a)
OneToOne
Species with no ortholog for C14orf37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf37 Gene

ENSEMBL:
Gene Tree for C14orf37 (if available)
TreeFam:
Gene Tree for C14orf37 (if available)

Paralogs for C14orf37 Gene

No data available for Paralogs for C14orf37 Gene

Variants for C14orf37 Gene

Sequence variations from dbSNP and Humsavar for C14orf37 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs111555 -- 58,054,045(+) ctgtg(A/G)aaagt intron-variant
rs115718 -- 58,059,463(-) TTTAA(G/T)TAGAG intron-variant
rs178473 -- 58,050,568(+) CTGAA(C/G)GTAAG intron-variant
rs178474 -- 58,051,134(+) ATCTA(C/G)TATTT intron-variant
rs178475 -- 58,052,417(+) TCATG(C/G)GAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf37 Gene

Variant ID Type Subtype PubMed ID
esv34185 CNV Loss 18971310
nsv507752 CNV Insertion 20534489
nsv826959 CNV Loss 20364138
esv2319201 CNV Deletion 18987734
esv2677940 CNV Deletion 23128226
esv2657771 CNV Deletion 23128226

Relevant External Links for C14orf37 Gene

HapMap Linkage Disequilibrium report
C14orf37

Disorders for C14orf37 Gene

Relevant External Links for C14orf37

Genetic Association Database (GAD)
C14orf37
Human Genome Epidemiology (HuGE) Navigator
C14orf37
genes like me logo Genes that share disorders with C14orf37: view

No data available for UniProtKB/Swiss-Prot for C14orf37 Gene

Publications for C14orf37 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. (PMID: 24925725) Chung S.A. … Langefeld C.D. (J. Am. Soc. Nephrol. 2014) 3
  4. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PMID: 20235792) Uhl G.R. … MunafA^ M.R. (Pharmacogenomics 2010) 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for C14orf37 Gene

  • antibodies-online peptides for C14orf37
  • antibodies-online antibodies for C14orf37
  • antibodies-online kits for C14orf37

Sources for C14orf37 Gene

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