C14orf28 Gene
protein-coding GIFtS: 37
GCID: GC14P045366
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chromosome 14 open reading frame 28
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Aliases
for C14orf28 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 14 Open Reading Frame 281 2 | | C14_52701 | | DRIP-11 2 | | Dopamine Receptor Interacting Protein 12 | | Dopamine Receptor-Interacting Protein 12 3 | | Uncharacterized Protein C14orf282 | | DRIP12 3 | | |
Export aliases for C14orf28 gene to outside databasesPrevious GC identifers: GC14P039162 GC14P043356 GC14P044436 GC14P025477 |
Summaries
for C14orf28 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C14orf28 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C14orf28 gene promoter:
HSF1 (long) POU6F1 (c2) POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 c-Ets-1 SRY FOXO1a HSF1short FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C14orf28
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C14orf28 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q21.2 Ensembl cytogenetic band: 14q21.2 HGNC cytogenetic band: 14q21.2C14orf28 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P045366: view genomic region
(about GC identifiers)
Start:
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45,366,498 bp from pter |
End:
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45,376,460 bp from pter |
Size:
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9,963 bases |
Orientation:
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plus strand |
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Proteins
for C14orf28 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CN028_HUMAN, Q4W4Y0 (See
protein sequence)Recommended Name: Uncharacterized protein C14orf28 Size: 310 amino acids; 36306 DaExplore the universe of human proteins at neXtProt for C14orf28: NX_Q4W4Y0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q4W4Y0
C14orf28 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001017923.1
ENSEMBL proteins: ENSP00000326846 ENSP00000451791
Human Recombinant Protein Products for C14orf28:
C14orf28 Antibody Products:
Assay Products for C14orf28: |
Protein
Domains /
Families
for C14orf28 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q4W4Y0 |
Function
for C14orf28 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C14orf28 (NM_001017923) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C14orf28 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C14orf28 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C14orf28 |
|
Pathways & Interactions
for C14orf28 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C14orf28
|
Drugs & Compounds
for C14orf28 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C14orf28
Search CenterWatch for drugs/clinical trials and news about C14orf28 / CN028
|
Transcripts
for C14orf28 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C14orf28 gene: NM_001017923.1 Unigene Cluster for C14orf28: Chromosome 14 open reading frame 28 Hs.82098 [show with all ESTs]Unigene Representative Sequence: NM_0010179234 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000325192(uc001wvo.3) ENST00000557112 ENST00000555826(uc001wvp.1)
ENST00000553841
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C14orf28 (NM_001017923) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C14orf28 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C14orf28 |
Additional cDNA sequence: AF250395.1 BC030258.1 BC105030.1 BC105032.1 2 DOTS entries: DT.99970323 DT.100674134 24/44 AceView cDNA sequences (see all 44): AI741798 AI339742 AA906110 AA257029 BM697310 AA256452 BU624091 CR602151 BM849739 BX113814 AI377372 AA256324 BU182551 AI480365 AA022589 BX361224 AA496213 W23966 BG104938 AK126985 AA732855 CD248747 BI826488 AA022590
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for C14orf28 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
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| SP1: | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C14orf28
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Expression
for C14orf28 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C14orf28 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTAATAAAAA
About this image
See C14orf28 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C14orf28
SOURCE GeneReport for Unigene cluster: Hs.82098
SABiosciences Custom PCR Arrays for C14orf28
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C14orf28
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C14orf28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C14orf28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C14orf28 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C14orf28 |
Orthologs
for C14orf28 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C14orf28 gene from 2/9 species (see all 9) About this table
ENSEMBL Gene Tree for C14orf28 (if available)
TreeFam Gene Tree for C14orf28 (if available) |
Paralogs
for C14orf28 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C14orf28 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C14orf28 (45366498 - 45376460 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C14orf28: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C14orf28 |
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Disorders
/ Diseases
for C14orf28 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C14orf28 for disorders About GeneDecksing
2  diseases for C14orf28: About MalaCardsbipolar disorder schizophrenia
Export disorders for C14orf28 gene to outside databases
|
Publications
for C14orf28 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C14orf28 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C14orf28) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Altered expression and coregulation of dopamine signa lling genes in schizophrenia and bipolar disorder. (PubMed id 20874815)1 Zhan L....Nasir J. (2011)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for C14orf28 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C14orf28 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C14orf28 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C14orf28 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C14orf28 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C14orf28 gene:
Search GeneIP for patents involving C14orf28
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C14orf28 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C14orf28 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C14orf28 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C14orf28 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C14orf28 | | OriGene 3'-UTR Clone for C14orf28 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C14orf28 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C14orf28 | | OriGene Custom Protein Services for C14orf28 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C14orf28 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C14orf28 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C14orf28 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C14orf28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C14orf28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C14orf28 |
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 | | | C14orf28 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C14orf28 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C14orf28 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C14orf28 |
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