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Aliases for C14orf28 Gene

Aliases for C14orf28 Gene

  • Chromosome 14 Open Reading Frame 28 2 3 5
  • Dopamine Receptor Interacting Protein 1 2 3
  • Dopamine Receptor-Interacting Protein 1 3 4
  • DRIP1 3 4
  • Uncharacterized Protein C14orf28 3
  • C14_5270 3
  • DRIP-1 3

External Ids for C14orf28 Gene

Previous GeneCards Identifiers for C14orf28 Gene

  • GC14P039162
  • GC14P043356
  • GC14P044436
  • GC14P045366
  • GC14P025477

Summaries for C14orf28 Gene

GeneCards Summary for C14orf28 Gene

C14orf28 (Chromosome 14 Open Reading Frame 28) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf28 Gene

Genomics for C14orf28 Gene

Regulatory Elements for C14orf28 Gene

Enhancers for C14orf28 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C14orf28 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf28 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C14orf28 Gene

44,897,295 bp from pter
44,907,257 bp from pter
9,963 bases
Plus strand

Genomic View for C14orf28 Gene

Genes around C14orf28 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf28 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf28 Gene

Proteins for C14orf28 Gene

  • Protein details for C14orf28 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C14orf28
    Protein Accession:

    Protein attributes for C14orf28 Gene

    310 amino acids
    Molecular mass:
    36306 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf28 Gene

Post-translational modifications for C14orf28 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C14orf28 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf28 Gene

Domains & Families for C14orf28 Gene

Protein Domains for C14orf28 Gene


Suggested Antigen Peptide Sequences for C14orf28 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf28: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C14orf28 Gene

Function for C14orf28 Gene

Phenotypes for C14orf28 Gene

GenomeRNAi human phenotypes for C14orf28:
genes like me logo Genes that share phenotypes with C14orf28: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf28 Gene

Localization for C14orf28 Gene

Subcellular locations from

Jensen Localization Image for C14orf28 Gene COMPARTMENTS Subcellular localization image for C14orf28 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C14orf28 Gene

Pathways & Interactions for C14orf28 Gene

SuperPathways for C14orf28 Gene

No Data Available

Interacting Proteins for C14orf28 Gene

Gene Ontology (GO) - Biological Process for C14orf28 Gene


No data available for Pathways by source and SIGNOR curated interactions for C14orf28 Gene

Drugs & Compounds for C14orf28 Gene

No Compound Related Data Available

Transcripts for C14orf28 Gene

Unigene Clusters for C14orf28 Gene

Chromosome 14 open reading frame 28:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf28 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b
SP1: -

Relevant External Links for C14orf28 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C14orf28 Gene

mRNA expression in normal human tissues for C14orf28 Gene

NURSA nuclear receptor signaling pathways regulating expression of C14orf28 Gene:


SOURCE GeneReport for Unigene cluster for C14orf28 Gene:

genes like me logo Genes that share expression patterns with C14orf28: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C14orf28 Gene

Orthologs for C14orf28 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf28 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C21H14orf28 34
  • 95 (n)
  • 98.21 (a)
C14orf28 35
  • 98 (a)
(Canis familiaris)
Mammalia C8H14orf28 34
  • 96.45 (n)
  • 97.74 (a)
C14ORF28 35
  • 98 (a)
(Mus musculus)
Mammalia Gm527 34
  • 93.87 (n)
  • 96.45 (a)
Gm527 16
Gm527 35
  • 96 (a)
(Pan troglodytes)
Mammalia C14H14orf28 34
  • 99.68 (n)
  • 99.35 (a)
C14orf28 35
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1307621 34
  • 94.41 (n)
  • 97.42 (a)
(Monodelphis domestica)
Mammalia C14orf28 35
  • 97 (a)
(Ornithorhynchus anatinus)
Mammalia C14orf28 35
  • 94 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494240 34
  • 76.02 (n)
  • 80.97 (a)
(Danio rerio)
Actinopterygii LOC100333462 34
  • 62.03 (n)
  • 66.02 (a)
C14orf28 35
  • 64 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7573 34
Species where no ortholog for C14orf28 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C14orf28 Gene

Gene Tree for C14orf28 (if available)
Gene Tree for C14orf28 (if available)

Paralogs for C14orf28 Gene

No data available for Paralogs for C14orf28 Gene

Variants for C14orf28 Gene

Sequence variations from dbSNP and Humsavar for C14orf28 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs35476805 -- 44,897,032(+) GGTTT(-/T)GCCAA upstream-variant-2KB
rs10150646 -- 44,895,886(+) CTCCA(G/T)CTAGC upstream-variant-2KB
rs10151061 -- 44,896,326(+) TCCCC(A/T)CCATA upstream-variant-2KB
rs58256296 -- 44,895,556(+) GGATT(C/T)TGAAA upstream-variant-2KB
rs73347158 -- 44,895,717(+) ATGCT(C/G)TATAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C14orf28 Gene

Variant ID Type Subtype PubMed ID
nsv1053437 CNV loss 25217958
nsv1258 CNV insertion 18451855
nsv564642 CNV loss 21841781

Variation tolerance for C14orf28 Gene

Residual Variation Intolerance Score: 63.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.30; 62.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf28 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf28 Gene

Disorders for C14orf28 Gene

Relevant External Links for C14orf28

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C14orf28 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf28 Gene

Publications for C14orf28 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  2. Altered expression and coregulation of dopamine signalling genes in schizophrenia and bipolar disorder. (PMID: 20874815) Zhan L. … Nasir J. (Neuropathol. Appl. Neurobiol. 2011) 3 65
  3. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3 65
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for C14orf28 Gene

Sources for C14orf28 Gene

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