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Aliases for C14orf180 Gene

Aliases for C14orf180 Gene

  • Chromosome 14 Open Reading Frame 180 2 3
  • C14orf77 3 4
  • NRAC 3 4
  • Nutritionally-Regulated Adipose And Cardiac Enriched Protein Homolog 3
  • Nutritionally-Regulated Adipose And Cardiac-Enriched 2
  • Chromosome 14 Open Reading Frame 77 2
  • Transmembrane Protein C14orf180 3

External Ids for C14orf180 Gene

Previous HGNC Symbols for C14orf180 Gene

  • C14orf77

Previous GeneCards Identifiers for C14orf180 Gene

  • GC14P104118
  • GC14P105046
  • GC14P085242

Summaries for C14orf180 Gene

GeneCards Summary for C14orf180 Gene

C14orf180 (Chromosome 14 Open Reading Frame 180) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf180 Gene

Genomics for C14orf180 Gene

Regulatory Elements for C14orf180 Gene

Genomic Location for C14orf180 Gene

Start:
104,579,684 bp from pter
End:
104,590,515 bp from pter
Size:
10,832 bases
Orientation:
Plus strand

Genomic View for C14orf180 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf180 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf180 Gene

Proteins for C14orf180 Gene

  • Protein details for C14orf180 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N912-NRAC_HUMAN
    Recommended name:
    Nutritionally-regulated adipose and cardiac enriched protein homolog
    Protein Accession:
    Q8N912
    Secondary Accessions:

    Protein attributes for C14orf180 Gene

    Size:
    160 amino acids
    Molecular mass:
    18051 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf180 Gene

Proteomics data for C14orf180 Gene at MOPED

Post-translational modifications for C14orf180 Gene

No Post-translational modifications

Other Protein References for C14orf180 Gene

No data available for DME Specific Peptides for C14orf180 Gene

Domains for C14orf180 Gene

Protein Domains for C14orf180 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C14orf180 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf180: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C14orf180 Gene

Function for C14orf180 Gene

Animal Model Products

CRISPR Products

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate C14orf180
    • Block miRNA regulation of C14orf180 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf180

    In Situ Assay Products

    Flow Cytometry Products

    No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C14orf180 Gene

    Localization for C14orf180 Gene

    Subcellular locations from UniProtKB/Swiss-Prot for C14orf180 Gene

    Cell membrane; Single-pass membrane protein.

    Subcellular locations from

    COMPARTMENTS
    Jensen Localization Image for C14orf180 Gene COMPARTMENTS Subcellular localization image for C14orf180 gene
    Compartment Confidence
    plasma membrane 5
    cytosol 1
    extracellular 1
    mitochondrion 1
    nucleus 1
    peroxisome 1

    Gene Ontology (GO) - Cellular Components for C14orf180 Gene

    GO ID Qualified GO term Evidence PubMed IDs
    GO:0005886 plasma membrane IEA --
    GO:0016021 integral component of membrane IEA --
    genes like me logo Genes that share ontologies with C14orf180: view

    Pathways for C14orf180 Gene

    SuperPathways for C14orf180 Gene

    No Data Available

    Interacting Proteins for C14orf180 Gene

    Gene Ontology (GO) - Biological Process for C14orf180 Gene

    None

    No data available for Pathways by source for C14orf180 Gene

    Transcripts for C14orf180 Gene

    mRNA/cDNA for C14orf180 Gene

    Unigene Clusters for C14orf180 Gene

    Chromosome 14 open reading frame 180:
    Representative Sequences:

    CRISPR Products

    miRNA Products

    • QIAGEN qRT-PCR Assays for microRNAs that regulate C14orf180
      • Block miRNA regulation of C14orf180 using miScript Target Protectors

      Inhibitory RNA Products

      • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf180

      Primer Products

      • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C14orf180

      Flow Cytometry Products

      Alternative Splicing Database (ASD) splice patterns (SP) for C14orf180 Gene

      No ASD Table

      Relevant External Links for C14orf180 Gene

      GeneLoc Exon Structure for
      C14orf180
      ECgene alternative splicing isoforms for
      C14orf180

      Expression for C14orf180 Gene

      mRNA expression in normal human tissues for C14orf180 Gene

      mRNA differential expression in normal tissues according to GTEx for C14orf180 Gene

      This gene is overexpressed in Heart - Left Ventricle (15.0), Heart - Atrial Appendage (13.3), Adipose - Visceral (Omentum) (7.4), and Adipose - Subcutaneous (5.1).

      SOURCE GeneReport for Unigene cluster for C14orf180 Gene Hs.153827

      genes like me logo Genes that share expressions with C14orf180: view

      In Situ Assay Products

      No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for C14orf180 Gene

      Orthologs for C14orf180 Gene

      This gene was present in the common ancestor of mammals.

      Orthologs for C14orf180 Gene

      Organism Taxonomy Gene Similarity Type Details
      chimpanzee
      (Pan troglodytes)
      Mammalia C14H14orf180 35
      • 98.54 (n)
      • 97.5 (a)
      C14orf180 36
      • 98 (a)
      OneToOne
      cow
      (Bos Taurus)
      Mammalia C14orf180 36
      • 60 (a)
      OneToOne
      NRAC 35
      • 75.47 (n)
      • 61.64 (a)
      dog
      (Canis familiaris)
      Mammalia C14orf180 36
      • 66 (a)
      OneToOne
      LOC612691 35
      • 77.85 (n)
      • 67.09 (a)
      mouse
      (Mus musculus)
      Mammalia A530016L24Rik 35
      • 67.1 (n)
      • 50.65 (a)
      A530016L24Rik 16
      A530016L24Rik 36
      • 48 (a)
      OneToOne
      oppossum
      (Monodelphis domestica)
      Mammalia C14orf180 36
      • 43 (a)
      OneToOne
      rat
      (Rattus norvegicus)
      Mammalia LOC691485 35
      • 69.37 (n)
      • 55 (a)
      Species with no ortholog for C14orf180:
      • A. gosspyii yeast (Ashbya gossypii)
      • Actinobacteria (Mycobacterium tuberculosis)
      • African clawed frog (Xenopus laevis)
      • African malaria mosquito (Anopheles gambiae)
      • Alicante grape (Vitis vinifera)
      • alpha proteobacteria (Wolbachia pipientis)
      • amoeba (Dictyostelium discoideum)
      • Archea (Pyrococcus horikoshii)
      • baker's yeast (Saccharomyces cerevisiae)
      • barley (Hordeum vulgare)
      • beta proteobacteria (Neisseria meningitidis)
      • bread mold (Neurospora crassa)
      • chicken (Gallus gallus)
      • Chromalveolata (Phytophthora infestans)
      • common water flea (Daphnia pulex)
      • corn (Zea mays)
      • E. coli (Escherichia coli)
      • filamentous fungi (Aspergillus nidulans)
      • Firmicute bacteria (Streptococcus pneumoniae)
      • fission yeast (Schizosaccharomyces pombe)
      • fruit fly (Drosophila melanogaster)
      • green algae (Chlamydomonas reinhardtii)
      • honey bee (Apis mellifera)
      • K. lactis yeast (Kluyveromyces lactis)
      • lizard (Anolis carolinensis)
      • loblloly pine (Pinus taeda)
      • malaria parasite (Plasmodium falciparum)
      • medicago trunc (Medicago Truncatula)
      • moss (Physcomitrella patens)
      • orangutan (Pongo pygmaeus)
      • pig (Sus scrofa)
      • platypus (Ornithorhynchus anatinus)
      • rainbow trout (Oncorhynchus mykiss)
      • rice (Oryza sativa)
      • rice blast fungus (Magnaporthe grisea)
      • schistosome parasite (Schistosoma mansoni)
      • sea anemone (Nematostella vectensis)
      • sea squirt (Ciona intestinalis)
      • sea squirt (Ciona savignyi)
      • sea urchin (Strongylocentrotus purpuratus)
      • sorghum (Sorghum bicolor)
      • soybean (Glycine max)
      • stem rust fungus (Puccinia graminis)
      • sugarcane (Saccharum officinarum)
      • thale cress (Arabidopsis thaliana)
      • tomato (Lycopersicon esculentum)
      • toxoplasmosis (Toxoplasma gondii)
      • Trichoplax (Trichoplax adhaerens)
      • tropical clawed frog (Silurana tropicalis)
      • wheat (Triticum aestivum)
      • worm (Caenorhabditis elegans)
      • zebrafish (Danio rerio)

      Evolution for C14orf180 Gene

      ENSEMBL:
      Gene Tree for C14orf180 (if available)
      TreeFam:
      Gene Tree for C14orf180 (if available)

      Paralogs for C14orf180 Gene

      Selected SIMAP similar genes for C14orf180 Gene using alignment to 1 proteins:

      genes like me logo Genes that share paralogs with C14orf180: view

      No data available for Paralogs for C14orf180 Gene

      Variants for C14orf180 Gene

      Sequence variations from dbSNP and Humsavar for C14orf180 Gene

      SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
      rs1134959 -- 104,589,768(+) CCGAC(C/G)ATCCA utr-variant-3-prime
      rs3803318 -- 104,589,022(-) CTCAC(A/G)TGGAC utr-variant-3-prime
      rs3840007 -- 104,589,336(-) GGGGG(-/G)TCAGA utr-variant-3-prime
      rs3840008 -- 104,588,955(-) CCCCC(-/C)ATGTC utr-variant-3-prime
      rs4270105 -- 104,582,205(+) GCCAG(C/T)GGGCG intron-variant

      Structural Variations from Database of Genomic Variants (DGV) for C14orf180 Gene

      Variant ID Type Subtype PubMed ID
      nsv902371 CNV Loss 21882294
      nsv902372 CNV Loss 21882294
      nsv902373 CNV Loss 21882294
      nsv470676 CNV Loss 18288195
      nsv456445 CNV Loss 19166990
      dgv2007n71 CNV Gain 21882294
      esv2749222 CNV Deletion 23290073
      esv2749223 CNV Deletion 23290073

      Relevant External Links for C14orf180 Gene

      HapMap Linkage Disequilibrium report
      C14orf180

      No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf180 Gene

      Disorders for C14orf180 Gene

      Relevant External Links for C14orf180

      Genetic Association Database (GAD)
      C14orf180
      genes like me logo Genes that share disorders with C14orf180: view

      No data available for UniProtKB/Swiss-Prot for C14orf180 Gene

      Publications for C14orf180 Gene

      1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
      2. Nrac, a novel nutritionally-regulated adipose and cardiac-enriched gene. (PMID: 23029450) Zhang R. … Abou-Samra A.B. (PLoS ONE 2012) 2 3
      3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
      4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

      Products for C14orf180 Gene

      • antibodies-online peptides for C14orf180
      • antibodies-online antibodies for C14orf180
      • antibodies-online kits for C14orf180

      Sources for C14orf180 Gene

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