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Aliases for C14orf178 Gene

Aliases for C14orf178 Gene

  • Chromosome 14 Open Reading Frame 178 2 3

External Ids for C14orf178 Gene

Previous GeneCards Identifiers for C14orf178 Gene

  • GC14P077297
  • GC14P078226
  • GC14P058393

Summaries for C14orf178 Gene

GeneCards Summary for C14orf178 Gene

C14orf178 (Chromosome 14 Open Reading Frame 178) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf178 Gene

Genomics for C14orf178 Gene

Regulatory Elements for C14orf178 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C14orf178 Gene

Chromosome:
14
Start:
77,760,830 bp from pter
End:
77,769,742 bp from pter
Size:
8,913 bases
Orientation:
Plus strand

Genomic View for C14orf178 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf178 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf178 Gene

Proteins for C14orf178 Gene

  • Protein details for C14orf178 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N769-CN178_HUMAN
    Recommended name:
    Uncharacterized protein C14orf178
    Protein Accession:
    Q8N769
    Secondary Accessions:
    • Q2HIX2
    • Q3KNR7

    Protein attributes for C14orf178 Gene

    Size:
    122 amino acids
    Molecular mass:
    13377 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C14orf178 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C14orf178 Gene

Proteomics data for C14orf178 Gene at MOPED

Post-translational modifications for C14orf178 Gene

No Post-translational modifications

Other Protein References for C14orf178 Gene

No data available for DME Specific Peptides for C14orf178 Gene

Domains & Families for C14orf178 Gene

Protein Domains for C14orf178 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf178: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf178 Gene

Function for C14orf178 Gene

Phenotypes for C14orf178 Gene

genes like me logo Genes that share phenotypes with C14orf178: view

Animal Model Products

CRISPR Products

miRNA for C14orf178 Gene

miRTarBase miRNAs that target C14orf178

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate C14orf178
    • Block miRNA regulation of C14orf178 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf178

    In Situ Assay Products

    Flow Cytometry Products

    No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf178 Gene

    Localization for C14orf178 Gene

    No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C14orf178 Gene

    Pathways & Interactions for C14orf178 Gene

    SuperPathways for C14orf178 Gene

    No Data Available

    Interacting Proteins for C14orf178 Gene

    Gene Ontology (GO) - Biological Process for C14orf178 Gene

    None

    No data available for Pathways by source and SIGNOR curated interactions for C14orf178 Gene

    Drugs & Compounds for C14orf178 Gene

    No Compound Related Data Available

    Transcripts for C14orf178 Gene

    mRNA/cDNA for C14orf178 Gene

    (2) REFSEQ mRNAs :
    (2) Selected AceView cDNA sequences:
    (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

    CRISPR Products

    miRNA Products

    • QIAGEN qRT-PCR Assays for microRNAs that regulate C14orf178
      • Block miRNA regulation of C14orf178 using miScript Target Protectors

      Inhibitory RNA Products

      • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf178

      Flow Cytometry Products

      Alternative Splicing Database (ASD) splice patterns (SP) for C14orf178 Gene

      No ASD Table

      Relevant External Links for C14orf178 Gene

      GeneLoc Exon Structure for
      C14orf178
      ECgene alternative splicing isoforms for
      C14orf178

      Expression for C14orf178 Gene

      mRNA expression in normal human tissues for C14orf178 Gene

      mRNA differential expression in normal tissues according to GTEx for C14orf178 Gene

      This gene is overexpressed in Testis (x9.8).

      SOURCE GeneReport for Unigene cluster for C14orf178 Gene Hs.375834

      genes like me logo Genes that share expression patterns with C14orf178: view

      Primer Products

      • QuantiTect SYBR Green Assays in human,mouse,rat
      • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
      • QuantiFast Probe-based Assays in human,mouse,rat

      In Situ Assay Products

      No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C14orf178 Gene

      Orthologs for C14orf178 Gene

      This gene was present in the common ancestor of human and chimp.

      Orthologs for C14orf178 Gene

      Organism Taxonomy Gene Similarity Type Details
      chimpanzee
      (Pan troglodytes)
      Mammalia C14H14orf178 35
      • 97.81 (n)
      • 95.9 (a)
      C14orf178 36
      • 96 (a)
      OneToOne
      Species with no ortholog for C14orf178:
      • A. gosspyii yeast (Ashbya gossypii)
      • Actinobacteria (Mycobacterium tuberculosis)
      • African clawed frog (Xenopus laevis)
      • African malaria mosquito (Anopheles gambiae)
      • Alicante grape (Vitis vinifera)
      • alpha proteobacteria (Wolbachia pipientis)
      • amoeba (Dictyostelium discoideum)
      • Archea (Pyrococcus horikoshii)
      • baker's yeast (Saccharomyces cerevisiae)
      • barley (Hordeum vulgare)
      • beta proteobacteria (Neisseria meningitidis)
      • bread mold (Neurospora crassa)
      • chicken (Gallus gallus)
      • Chromalveolata (Phytophthora infestans)
      • common water flea (Daphnia pulex)
      • corn (Zea mays)
      • cow (Bos Taurus)
      • dog (Canis familiaris)
      • E. coli (Escherichia coli)
      • filamentous fungi (Aspergillus nidulans)
      • Firmicute bacteria (Streptococcus pneumoniae)
      • fission yeast (Schizosaccharomyces pombe)
      • fruit fly (Drosophila melanogaster)
      • green algae (Chlamydomonas reinhardtii)
      • honey bee (Apis mellifera)
      • K. lactis yeast (Kluyveromyces lactis)
      • lizard (Anolis carolinensis)
      • loblloly pine (Pinus taeda)
      • malaria parasite (Plasmodium falciparum)
      • medicago trunc (Medicago Truncatula)
      • moss (Physcomitrella patens)
      • mouse (Mus musculus)
      • oppossum (Monodelphis domestica)
      • orangutan (Pongo pygmaeus)
      • pig (Sus scrofa)
      • platypus (Ornithorhynchus anatinus)
      • rainbow trout (Oncorhynchus mykiss)
      • rat (Rattus norvegicus)
      • rice (Oryza sativa)
      • rice blast fungus (Magnaporthe grisea)
      • schistosome parasite (Schistosoma mansoni)
      • sea anemone (Nematostella vectensis)
      • sea squirt (Ciona intestinalis)
      • sea squirt (Ciona savignyi)
      • sea urchin (Strongylocentrotus purpuratus)
      • sorghum (Sorghum bicolor)
      • soybean (Glycine max)
      • stem rust fungus (Puccinia graminis)
      • sugarcane (Saccharum officinarum)
      • thale cress (Arabidopsis thaliana)
      • tomato (Lycopersicon esculentum)
      • toxoplasmosis (Toxoplasma gondii)
      • Trichoplax (Trichoplax adhaerens)
      • tropical clawed frog (Silurana tropicalis)
      • wheat (Triticum aestivum)
      • worm (Caenorhabditis elegans)
      • zebrafish (Danio rerio)

      Evolution for C14orf178 Gene

      ENSEMBL:
      Gene Tree for C14orf178 (if available)
      TreeFam:
      Gene Tree for C14orf178 (if available)

      Paralogs for C14orf178 Gene

      genes like me logo Genes that share paralogs with C14orf178: view

      No data available for Paralogs for C14orf178 Gene

      Variants for C14orf178 Gene

      Sequence variations from dbSNP and Humsavar for C14orf178 Gene

      SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
      rs1978417 -- 77,768,441(+) ttttt(A/T)ttttt intron-variant
      rs3759728 -- 77,763,816(-) TTGTA(A/T)CACGT intron-variant
      rs6574399 -- 77,764,624(+) CCACC(A/T)CACCG intron-variant
      rs7142390 -- 77,766,537(+) ataga(C/T)tcata intron-variant
      rs7145717 -- 77,766,883(+) ataga(A/G)aaatt intron-variant

      Structural Variations from Database of Genomic Variants (DGV) for C14orf178 Gene

      Variant ID Type Subtype PubMed ID
      dgv643e1 CNV Complex 17122850

      Variation tolerance for C14orf178 Gene

      Residual Variation Intolerance Score: 64.57% of all genes are more intolerant (likely to be disease-causing)
      Gene Damage Index Score: 3.65; 56.85% of all genes are more intolerant (likely to be disease-causing)

      Relevant External Links for C14orf178 Gene

      HapMap Linkage Disequilibrium report
      C14orf178

      No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf178 Gene

      Disorders for C14orf178 Gene

      Relevant External Links for C14orf178

      Atlas of Genetics and Cytogenetics in Oncology and Haematology:
      C14orf178
      genes like me logo Genes that share disorders with C14orf178: view

      No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf178 Gene

      Publications for C14orf178 Gene

      1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
      2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
      3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
      4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 67

      Products for C14orf178 Gene

      • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
      • QIAGEN qRT-PCR Assays for microRNAs that regulate C14orf178
        • QuantiTect SYBR Green Assays in human,mouse,rat
        • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
        • QuantiFast Probe-based Assays in human,mouse,rat
        • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf178
        • Block miRNA regulation of C14orf178 using miScript Target Protectors

        Sources for C14orf178 Gene

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