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Aliases for C14orf178 Gene

Aliases for C14orf178 Gene

  • Chromosome 14 Open Reading Frame 178 2 3 5

External Ids for C14orf178 Gene

Previous GeneCards Identifiers for C14orf178 Gene

  • GC14P077297
  • GC14P078226
  • GC14P058393

Summaries for C14orf178 Gene

GeneCards Summary for C14orf178 Gene

C14orf178 (Chromosome 14 Open Reading Frame 178) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf178 Gene

Genomics for C14orf178 Gene

Regulatory Elements for C14orf178 Gene

Enhancers for C14orf178 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F077799 1.1 ENCODE 19.6 +39.5 39455 1.5 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 ZNF207 ZNF143 FOS SP3 RPL21P10 ZMYND19P1 C14orf178 ALKBH1 SNW1 RPL22P2 ADCK1 ENSG00000199440 GC14M077822
GH14F077759 1 ENCODE 21.5 +0.1 109 2.5 ATF1 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF48 ZNF2 ETS1 YY1 RPL21P10 C14orf178 ZMYND19P1 ADCK1 SNW1
GH14F077795 1 Ensembl ENCODE 17.6 +35.4 35423 1.5 GTF2F1 TEAD1 HLF JUN MAX CEBPB CEBPG EP300 TEAD3 JUND C14orf178 SLIRP ADCK1 SNW1
GH14F077663 1.1 FANTOM5 Ensembl ENCODE 13.4 -97.1 -97128 0.9 ESRRA PKNOX1 CEBPB MNT ZFHX2 FOSL2 FOS EGR2 ADCK1 C14orf178 SLIRP SNW1 RPL21P10 GC14P077671 COX6CP11
GH14F077729 0.5 ENCODE 26.4 -29.9 -29940 2.0 PAF1 CTCF MAFK ADCK1 C14orf178 SNW1 ALKBH1 SLIRP RPL21P10
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C14orf178 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf178 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000421396 170 2400 ATF1 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF48 ZNF2 ETS1 YY1

Genomic Location for C14orf178 Gene

Chromosome:
14
Start:
77,760,830 bp from pter
End:
77,769,742 bp from pter
Size:
8,913 bases
Orientation:
Plus strand

Genomic View for C14orf178 Gene

Genes around C14orf178 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf178 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf178 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf178 Gene

Proteins for C14orf178 Gene

  • Protein details for C14orf178 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N769-CN178_HUMAN
    Recommended name:
    Uncharacterized protein C14orf178
    Protein Accession:
    Q8N769
    Secondary Accessions:
    • Q2HIX2
    • Q3KNR7

    Protein attributes for C14orf178 Gene

    Size:
    122 amino acids
    Molecular mass:
    13377 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C14orf178 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C14orf178 Gene

Post-translational modifications for C14orf178 Gene

No Post-translational modifications

Other Protein References for C14orf178 Gene

No data available for DME Specific Peptides for C14orf178 Gene

Domains & Families for C14orf178 Gene

Protein Domains for C14orf178 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf178: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf178 Gene

Function for C14orf178 Gene

genes like me logo Genes that share phenotypes with C14orf178: view

Animal Model Products

miRNA for C14orf178 Gene

miRTarBase miRNAs that target C14orf178

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf178 Gene

Localization for C14orf178 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C14orf178 gene
Compartment Confidence
extracellular 2
nucleus 2
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C14orf178 Gene

Pathways & Interactions for C14orf178 Gene

SuperPathways for C14orf178 Gene

No Data Available

Interacting Proteins for C14orf178 Gene

Selected Interacting proteins: Q8N769-CN178_HUMAN for C14orf178 Gene via IID

Symbol External ID(s) Details
SETX

Gene Ontology (GO) - Biological Process for C14orf178 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf178 Gene

Transcripts for C14orf178 Gene

mRNA/cDNA for C14orf178 Gene

(2) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf178 Gene

No ASD Table

Relevant External Links for C14orf178 Gene

GeneLoc Exon Structure for
C14orf178
ECgene alternative splicing isoforms for
C14orf178

Expression for C14orf178 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C14orf178 Gene

mRNA differential expression in normal tissues according to GTEx for C14orf178 Gene

This gene is overexpressed in Testis (x9.8).

NURSA nuclear receptor signaling pathways regulating expression of C14orf178 Gene:

C14orf178

SOURCE GeneReport for Unigene cluster for C14orf178 Gene:

Hs.375834
genes like me logo Genes that share expression patterns with C14orf178: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C14orf178 Gene

Orthologs for C14orf178 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C14orf178 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf178 34
  • 97.81 (n)
C14orf178 35
  • 96 (a)
OneToOne
Species where no ortholog for C14orf178 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf178 Gene

ENSEMBL:
Gene Tree for C14orf178 (if available)
TreeFam:
Gene Tree for C14orf178 (if available)

Paralogs for C14orf178 Gene

genes like me logo Genes that share paralogs with C14orf178: view

No data available for Paralogs for C14orf178 Gene

Variants for C14orf178 Gene

Sequence variations from dbSNP and Humsavar for C14orf178 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10144448 -- 77,767,569(+) ggtga(C/T)ggttg intron-variant
rs10718313 -- 77,759,157(+) GGAGT(-/C)CTCAA intron-variant, upstream-variant-2KB
rs111447148 -- 77,762,142(+) ACCCT(A/G)TCTCT intron-variant, upstream-variant-2KB
rs113007070 -- 77,761,064(+) AGAAG(A/G)CTGGT intron-variant, reference, missense, utr-variant-5-prime
rs11300907 -- 77,766,138(+) ATCTC(-/T)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf178 Gene

Variant ID Type Subtype PubMed ID
esv2759998 CNV gain 17122850

Variation tolerance for C14orf178 Gene

Residual Variation Intolerance Score: 64.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.65; 56.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf178 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C14orf178

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf178 Gene

Disorders for C14orf178 Gene

Relevant External Links for C14orf178

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf178

No disorders were found for C14orf178 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf178 Gene

Publications for C14orf178 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64

Products for C14orf178 Gene

Sources for C14orf178 Gene

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