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Aliases for C14orf177 Gene

Aliases for C14orf177 Gene

  • Chromosome 14 Open Reading Frame 177 2 3

External Ids for C14orf177 Gene

Previous GeneCards Identifiers for C14orf177 Gene

  • GC14P098250
  • GC14P099177
  • GC14P079360

Summaries for C14orf177 Gene

GeneCards Summary for C14orf177 Gene

C14orf177 (Chromosome 14 Open Reading Frame 177) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf177 Gene

Genomics for C14orf177 Gene

Regulatory Elements for C14orf177 Gene

Genomic Location for C14orf177 Gene

98,711,613 bp from pter
98,717,766 bp from pter
6,154 bases
Plus strand

Genomic View for C14orf177 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf177 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf177 Gene

Proteins for C14orf177 Gene

  • Protein details for C14orf177 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C14orf177
    Protein Accession:
    Secondary Accessions:
    • Q8N7D2

    Protein attributes for C14orf177 Gene

    125 amino acids
    Molecular mass:
    13861 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf177 Gene

Proteomics data for C14orf177 Gene at MOPED

Post-translational modifications for C14orf177 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C14orf177 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf177 Gene

Domains & Families for C14orf177 Gene

Protein Domains for C14orf177 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf177: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf177 Gene

Function for C14orf177 Gene

genes like me logo Genes that share phenotypes with C14orf177: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf177

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C14orf177 Gene

Localization for C14orf177 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C14orf177 Gene

Pathways & Interactions for C14orf177 Gene

SuperPathways for C14orf177 Gene

No Data Available

Interacting Proteins for C14orf177 Gene

Gene Ontology (GO) - Biological Process for C14orf177 Gene


No data available for Pathways by source and SIGNOR curated interactions for C14orf177 Gene

Drugs & Compounds for C14orf177 Gene

No Compound Related Data Available

Transcripts for C14orf177 Gene

mRNA/cDNA for C14orf177 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C14orf177 Gene

Chromosome 14 open reading frame 177:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf177

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf177 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1: -

Relevant External Links for C14orf177 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C14orf177 Gene

mRNA expression in normal human tissues for C14orf177 Gene

mRNA differential expression in normal tissues according to GTEx for C14orf177 Gene

This gene is overexpressed in Testis (x50.0).

SOURCE GeneReport for Unigene cluster for C14orf177 Gene Hs.448754

genes like me logo Genes that share expression patterns with C14orf177: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C14orf177 Gene

Orthologs for C14orf177 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C14orf177 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C14H14orf177 35
  • 97.87 (n)
  • 98.4 (a)
C14orf177 36
  • 98 (a)
Species with no ortholog for C14orf177:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf177 Gene

Gene Tree for C14orf177 (if available)
Gene Tree for C14orf177 (if available)

Paralogs for C14orf177 Gene

No data available for Paralogs for C14orf177 Gene

Variants for C14orf177 Gene

Sequence variations from dbSNP and Humsavar for C14orf177 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1467455 -- 98,713,324(+) cttct(C/G)tacaa intron-variant
rs1467456 -- 98,713,786(+) gccta(G/T)gtgac intron-variant
rs1543422 -- 98,716,434(+) TCACT(A/G)TATTC intron-variant
rs1950489 -- 98,711,970(+) ACCCT(C/T)TTGGG intron-variant
rs1955907 -- 98,716,339(+) AGAGC(A/C/T)TAAGA missense, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C14orf177 Gene

Variant ID Type Subtype PubMed ID
nsv456417 CNV Loss 19166990
nsv516436 CNV Loss 19592680
esv2665034 CNV Deletion 23128226

Variation tolerance for C14orf177 Gene

Residual Variation Intolerance Score: 78.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.00; 49.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf177 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf177 Gene

Disorders for C14orf177 Gene

Relevant External Links for C14orf177

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C14orf177: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf177 Gene

Publications for C14orf177 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 67
  3. Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. (PMID: 23118302) Chu A.Y. … Ridker P.M. (Circ Cardiovasc Genet 2012) 67
  4. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 67
  5. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PMID: 17903307) Wilk J.B. … O'Connor G.T. (BMC Med. Genet. 2007) 67

Products for C14orf177 Gene

Sources for C14orf177 Gene

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