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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C14orf169 Gene

protein-coding   GIFtS: 41
GCID: GC14P073958

chromosome 14 open reading frame 169
 Explore 3 diseases affiliated with
C14orf169 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for C14orf169    

Aliases
for C14orf169 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Chromosome 14 Open Reading Frame 1691 2     ROX2 3
MAPJD1 2 3 5     HsNO661
NO661 2 5     FLJ218021
Histone Lysine Demethylase NO662 3     Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase NO662
Myc-Associated Protein With JmjC Domain2 3     Lysine-Specific Demethylase NO662
Nucleolar Protein 662 3     EC 1.14.11.-3
Ribosomal Oxygenase NO662 3     EC 1.14.11.273
60S Ribosomal Protein L8 Histidine Hydroxylase2 3     

External Ids:    HGNC: 209681   Entrez Gene: 796972   Ensembl: ENSG000002552427   OMIM: 6119195   UniProtKB: Q9H6W33   

Export aliases for C14orf169 gene to outside databases

Previous GC identifers: GC14P071948 GC14P071949 GC14P073027 GC14P054124


Summaries
for C14orf169 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NO66_HUMAN, Q9H6W3
Function: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in
histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1)
residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of
60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with
SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity).
May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
Participates in MYC-induced transcriptional activation




Genomic Views
for C14orf169 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C14orf169 gene promoter:
         USF1   Pax-2b   USF-1   Nkx2-2   Pax-6   Pax-2   Pax-2a   ITF-2   Tal-1beta   C/EBPalpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C14orf169

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C14orf169


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.3   Ensembl cytogenetic band:  14q24.3   HGNC cytogenetic band: 14q24.3

C14orf169 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C14orf169 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P073958:  view genomic region     (about GC identifiers)

Start:
 73,957,644 bp from pter      End:
 73,960,105 bp from pter
Size:
 2,462 bases      Orientation:
 plus strand

Proteins
for C14orf169 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NO66_HUMAN, Q9H6W3 (See protein sequence)
Recommended Name: Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66  
Size: 641 amino acids; 71086 Da
Cofactor: Binds 1 Fe(2+) ion per subunit (By similarity)
Subunit: Interacts with SP7/OSX; the interaction is direct (By similarity). Interacts with MYC. Interacts with PHF19;
leading to its recruitment to H3K36me3 sites
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Granular part of nucleoli. Nucleoplasm,
nucleoplasmic foci, some of them associated with nucleoli
2 PDB 3D structures from and Proteopedia for C14orf169:
4DIQ (3D)        4E4H (3D)    
Secondary accessions: B4DT02
Alternative splicing: 2 isoforms:  Q9H6W3-1   Q9H6W3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for C14orf169: NX_Q9H6W3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H6W3

    • C14orf169 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_078920.2  
    Human Recombinant Protein Products: 
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    Novus Biologicals C14orf169 Protein
    Novus Biologicals C14orf169 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for C14orf169

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005654nucleoplasm IEA--
    GO:0005730nucleolus IEA--


    C14orf169 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for C14orf169

    Protein Domains /
    Families
    for C14orf169 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    C14orf169 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR003347 JmjC_dom
     IPR013109 NO66/MINA

    Graphical View of Domain Structure for InterPro Entry Q9H6W3

    ProtoNet protein and cluster: Q9H6W3

    2 Blocks protein families:
    IPB003347 Transcription factor jumonji
    IPB013109 Cupin 4


    UniProtKB/Swiss-Prot: NO66_HUMAN, Q9H6W3
    Similarity: Belongs to the MINA53/NO66 family. NO66 subfamily
    Similarity: Contains 1 JmjC domain


    Function
    for C14orf169 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NO66_HUMAN, Q9H6W3
    Function: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
    Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in
    histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1)
    residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of
    60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with
    SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity).
    May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
    Participates in MYC-induced transcriptional activation
    Catalytic activity: Protein N(6),N(6)-dimethyl-L-lysine + 2-oxoglutarate + O(2) = protein N(6)-methyl-L-lysine +
    succinate + formaldehyde + CO(2)
    Catalytic activity: Protein N(6)-methyl-L-lysine + 2-oxoglutarate + O(2) = protein L-lysine + succinate + formaldehyde
    + CO(2)
    Catalytic activity: L-histidine-[60S ribosomal protein L8] + 2-oxoglutarate + O(2) = (3S)-3-hydroxy-L-histidine-[60S
    ribosomal protein L8] + succinate + CO(2)

    Enzyme Numbers (IUBMB): EC 1.14.11.-1 EC 1.14.11.271

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate C14orf169:
    hsa-miR-146a* hsa-miR-495 hsa-miR-1271 hsa-miR-485-3p hsa-miR-514b-5p hsa-miR-513c hsa-miR-96 hsa-miR-3907
    SwitchGear 3'UTR luciferase reporter plasmid: C14orf169 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005506iron ion binding ISS--
    GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA--
    GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors ISS--
    GO:0032453histone demethylase activity (H3-K4 specific) ISS--
    GO:0051864histone demethylase activity (H3-K36 specific) ISS--


    C14orf169 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for C14orf169:
     Decreased viability with TRAIL 


    Pathways & Interactions
    for C14orf169 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C14orf169

    5/9 Interacting proteins for C14orf169 (Q9H6W32, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP2CAP677753I2D: score=2 
    TRAPPC6BQ86SZ23I2D: score=2 
    USP42Q9H9J43I2D: score=2 
    BCAR1P569453I2D: score=1 
    KAT5Q929933I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0034720histone H3-K4 demethylation ISS--
    GO:0045668negative regulation of osteoblast differentiation ISS--
    GO:0045892negative regulation of transcription, DNA-dependent ISS--
    GO:0070544histone H3-K36 demethylation ISS--


    C14orf169 for ontologies           About GeneDecksing



    Drugs & Compounds
    for C14orf169 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C14orf169
    Search CenterWatch for drugs/clinical trials and news about C14orf169 / NO66 

    Transcripts
    for C14orf169 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for C14orf169 gene: 
    NM_024644.3  

    Unigene Cluster for C14orf169:

    Chromosome 14 open reading frame 169
    Hs.509916  [show with all ESTs]
    Unigene Representative Sequence: NM_024644
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000531973

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate C14orf169:
    hsa-miR-146a* hsa-miR-495 hsa-miR-1271 hsa-miR-485-3p hsa-miR-514b-5p hsa-miR-513c hsa-miR-96 hsa-miR-3907
    SwitchGear 3'UTR luciferase reporter plasmid: C14orf169 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C14orf169 (see all 4)
    OriGene shRNA RFP: C14orf169
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C14orf169
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C14orf169

    Additional cDNA sequence: 

    AK025455.1 AK299994.1 AY390535.1 BC011350.1 BC071954.1 

    4 DOTS entries:

    DT.408891  DT.120758296  DT.102842734  DT.91687878 

    24/57 AceView cDNA sequences (see all 57):

    BM923853 BG108325 BI257802 BF221583 BG610839 BG107618 BE784665 Z40969 
    BQ924940 BX384677 BQ018771 BX363489 BM040984 BI913225 BX342600 AA576870 
    BX390965 BC071954 AW769847 NM_024644 AK025455 BF000100 BF194857 CB528504 

    GeneLoc Exon Structure


    Expression
    for C14orf169 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C14orf169 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCGGGTCGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See C14orf169 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C14orf169

    SOURCE GeneReport for Unigene cluster: Hs.509916

    UniProtKB/Swiss-Prot: NO66_HUMAN, Q9H6W3
    Tissue specificity: Widely expressed. Overexpressed in lung carcinomas

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    In Situ
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    Orthologs
    for C14orf169 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for C14orf169 gene from 5/8 species (see all 8)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia 2410016O06Rik1 , 5 RIKEN cDNA 2410016O06 gene1, 5 81.97(n)1
    83.33(a)1    		   12 (38.97 cM)5
    719521  NM_023633.31  NP_076122.21 
     839506085 
    chicken
    (Gallus gallus)    		 Aves C5H14orf1691 chromosome 5 open reading frame, human C14orf169 62.31(n)
    58.22(a)    		   423249  NM_001031196.1  NP_001026367.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.43342 Transcribed sequence with weak similarity to protein refNP_078920.1 (H.sapiens) hypothetical protein FLJ21802 [Homo sapiens] less 74.54(n)    CB360227.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG29821 CG2982 51.7(n)
    41.44(a)    		   31374  NM_131932.3  NP_572160.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea jmjc-11 Protein JMJC-1 46.56(n)
    37.56(a)    		   171932  NM_001026473.3  NP_001021644.1 


    ENSEMBL Gene Tree for C14orf169 (if available)
    TreeFam Gene Tree for C14orf169 (if available) 

    Paralogs
    for C14orf169 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for C14orf169 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/73 NCBI SNPs in C14orf169 are shown (see all 73)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1157839341,2
    		F,--73955702(+) AGAGGT/CTGGGG 3 -- int1 us2k11Minor allele frequency- C:0.02WA 118
    rs1384380291,2
    		C,--73955706(+) GTTGGG/TGTAAC 3 -- us2k1 int10--------
    rs1426173011,2
    		C,--73955820(+) ACTAC-/ACTACTAC 3 -- int1 us2k10--------
    rs788532441,2
    		C--73955826(+) CTACT-/ACTGACAT 3 -- us2k1 int10--------
    rs1867895041,2
    		--73955929(+) ACAACA/CCCTAG 3 -- us2k1 int10--------
    rs71568751,2
    		C,F,H,--73955933(+) CCCCTC/AGCCCC 3 -- us2k1 int123Minor allele frequency- A:0.18NS EA WA NA CSA 2349
    rs776633001,2
    		C,F,--73955985(+) CCCCAG/ATTGAT 3 -- int1 us2k11Minor allele frequency- A:0.05EA 120
    rs1416324831,2
    		--73955995(+) TAACTG/TTGTGT 3 -- int1 us2k10--------
    rs80032941,2
    		C,F,H,--73956386(+) ACCACA/GTTGCC 3 -- us2k1 int17Minor allele frequency- G:0.02NS NA WA 912
    rs1507553051,2
    		--73956440(+) AAGAAA/GTTGTA 3 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for C14orf169 (73957644 - 73960105 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for C14orf169: --

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    Disorders / Diseases
    for C14orf169 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    C14orf169 for disorders           About GeneDecksing

    OMIM gene information: 611919    OMIM disorders: --

    3 diseases for C14orf169:    About MalaCards
    lung cancer    lung carcinoma    carcinoma


    Export disorders for C14orf169 gene to outside databases

    Publications
    for C14orf169 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C14orf169 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with C14orf169)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer. (PubMed id 17308053)1, 2, 3 Suzuki C....Daigo Y. (2007)
    2. Purification, crystallization and preliminary crystall ographic analysis of histone lysine demethylase NO66 from Homo sapiens. (PubMed id 22750859)1, 3 Zhou X....Zang J. (2012)
    3. Regulation of the osteoblast-specific transcription f actor Osterix by NO66, a Jumonji family histone demethylase. (PubMed id 19927124)1, 3 Sinha K.M....de Crombrugghe B. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. (PubMed id 14742713)1, 2 Eilbracht J.... Schmidt-Zachmann M.S. (2004)
    7. Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans. (PubMed id 23103944)2 Ge W....Schofield C.J. (2012)
    8. Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation. (PubMed id 23160351)2 Brien G.L.... Bracken A.P. (2012)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    10. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)

    External Searches for C14orf169 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing C14orf169 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79697 HGNC: 20968 AceView: C14orf169 Ensembl:ENSG00000255242 euGenes: HUgn79697
    ECgene: C14orf169 H-InvDB: C14orf169

    Other Databases showing C14orf169 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing C14orf169 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C14orf169 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for C14orf169 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for C14orf169 gene:
    Search GeneIP for patents involving C14orf169

    GeneCards and IP:
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