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Aliases for C14orf159 Gene

Aliases for C14orf159 Gene

  • Chromosome 14 Open Reading Frame 159 2 3

External Ids for C14orf159 Gene

Previous GeneCards Identifiers for C14orf159 Gene

  • GC14P089570
  • GC14P089571
  • GC14P090650
  • GC14P091580
  • GC14P071755
  • GC14P091526

Summaries for C14orf159 Gene

GeneCards Summary for C14orf159 Gene

C14orf159 (Chromosome 14 Open Reading Frame 159) is a Protein Coding gene.

Gene Wiki entry for C14orf159 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf159 Gene

Genomics for C14orf159 Gene

Regulatory Elements for C14orf159 Gene

Genomic Location for C14orf159 Gene

Start:
91,060,333 bp from pter
End:
91,225,632 bp from pter
Size:
165,300 bases
Orientation:
Plus strand

Genomic View for C14orf159 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf159 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf159 Gene

Proteins for C14orf159 Gene

  • Protein details for C14orf159 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3D6-CN159_HUMAN
    Recommended name:
    UPF0317 protein C14orf159, mitochondrial
    Protein Accession:
    Q7Z3D6
    Secondary Accessions:
    • B3KUI7
    • Q86SW3
    • Q86SX8
    • Q86SX9
    • Q86T08
    • Q86TV5
    • Q96GW5
    • Q9H7G0
    • Q9H8Y9
    • Q9H9W6

    Protein attributes for C14orf159 Gene

    Size:
    616 amino acids
    Molecular mass:
    66437 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14932.1; Type=Frameshift; Positions=436, 582; Evidence={ECO:0000305};

    Alternative splice isoforms for C14orf159 Gene

neXtProt entry for C14orf159 Gene

Proteomics data for C14orf159 Gene at MOPED

Post-translational modifications for C14orf159 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for C14orf159 Gene

Domains for C14orf159 Gene

Protein Domains for C14orf159 Gene

Suggested Antigen Peptide Sequences for C14orf159 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z3D6

UniProtKB/Swiss-Prot:

CN159_HUMAN :
  • Q7Z3D6
Family:
  • Belongs to the UPF0317 family.
genes like me logo Genes that share domains with C14orf159: view

No data available for Gene Families for C14orf159 Gene

Function for C14orf159 Gene

Gene Ontology (GO) - Molecular Function for C14orf159 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C14orf159: view

Phenotypes for C14orf159 Gene

GenomeRNAi human phenotypes for C14orf159:
genes like me logo Genes that share phenotypes with C14orf159: view

Animal Model Products

CRISPR Products

miRNA for C14orf159 Gene

miRTarBase miRNAs that target C14orf159

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C14orf159 Gene

Localization for C14orf159 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf159 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf159 Gene COMPARTMENTS Subcellular localization image for C14orf159 gene
Compartment Confidence
mitochondrion 3
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for C14orf159 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with C14orf159: view

Pathways for C14orf159 Gene

SuperPathways for C14orf159 Gene

No Data Available

Interacting Proteins for C14orf159 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000256324%0d%0a9606.ENSP00000216455%0d%0a
Selected Interacting proteins: ENSP00000256324 Q7Z3D6-CN159_HUMAN for C14orf159 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C14orf159 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C14orf159: view

No data available for Pathways by source for C14orf159 Gene

Transcripts for C14orf159 Gene

Unigene Clusters for C14orf159 Gene

Chromosome 14 open reading frame 159:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf159

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf159 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d ^ 10a · 10b ^ 11a · 11b · 11c ·
SP1: - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - -
SP5: - - - - - - - - - - - - - -
SP6: - - - - - - - - - - -
SP7: - - - - - -
SP8: - - - - - - - - -
SP9: - - - - - - - - - - - - - - - - - - -
SP10: - - - - - - - - - -
SP11: - - - - - - - - - -
SP12: - - - - - - - - - - - - - - -
SP13: - - - - - - - - - - - - -
SP14: - - - - - - - -
SP15: - - - - - - -
SP16:
SP17:
SP18:
SP19:
SP20: -

ExUns: 11d · 11e ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21a · 21b ^ 22a · 22b ^ 23a · 23b · 23c
SP1: - - -
SP2: - - - - -
SP3: - - - - - - -
SP4: - - - - -
SP5: - - -
SP6: - - - - -
SP7: - - - - -
SP8:
SP9: - - -
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17: - -
SP18: -
SP19:
SP20:

Relevant External Links for C14orf159 Gene

GeneLoc Exon Structure for
C14orf159
ECgene alternative splicing isoforms for
C14orf159

Expression for C14orf159 Gene

mRNA expression in normal human tissues for C14orf159 Gene

Protein differential expression in normal tissues for C14orf159 Gene

This gene is overexpressed in Heart (15.3) and Uterus (6.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C14orf159 Gene

SOURCE GeneReport for Unigene cluster for C14orf159 Gene Hs.309849

genes like me logo Genes that share expressions with C14orf159: view

Expression partners for C14orf159 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C14orf159 Gene

Orthologs for C14orf159 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for C14orf159 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia 9030617O03Rik 35
  • 78.93 (n)
  • 75.04 (a)
9030617O03Rik 16
9030617O03Rik 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf159 35
  • 99.03 (n)
  • 98.71 (a)
C14orf159 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311756 35
  • 79.53 (n)
  • 76.87 (a)
cow
(Bos Taurus)
Mammalia C14orf159 36
  • 58 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C14orf159 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf159 36
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H14ORF159 35
  • 62.85 (n)
  • 60.46 (a)
C14orf159 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C14orf159 36
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c14orf159 35
  • 59.72 (n)
  • 55.83 (a)
Str.20422 35
zebrafish
(Danio rerio)
Actinopterygii c14orf159 35
  • 59.74 (n)
  • 52.92 (a)
wufj56e06 35
C17H14orf159 36
  • 51 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6256 35
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C19041g 35
  • 41.04 (n)
  • 32 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC5H10.01 35
  • 42.68 (n)
  • 30.49 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
OneToMany
-- 36
  • 28 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
Species with no ortholog for C14orf159:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C14orf159 Gene

ENSEMBL:
Gene Tree for C14orf159 (if available)
TreeFam:
Gene Tree for C14orf159 (if available)

Paralogs for C14orf159 Gene

genes like me logo Genes that share paralogs with C14orf159: view

No data available for Paralogs for C14orf159 Gene

Variants for C14orf159 Gene

Sequence variations from dbSNP and Humsavar for C14orf159 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs6562 -- 91,225,127(-) TCTCA(C/T)AGGAG utr-variant-3-prime
rs933530 -- 91,137,631(-) gatca(C/T)gaggt intron-variant
rs941672 -- 91,120,210(-) GCCCG(A/G)AGGAG intron-variant
rs941673 -- 91,119,669(-) CTTCA(A/G)TCCAA intron-variant
rs941674 -- 91,119,578(-) CCCAG(A/G)GGATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf159 Gene

Variant ID Type Subtype PubMed ID
dgv141n21 CNV Gain 19592680
nsv1394 CNV Insertion 18451855
nsv832857 CNV Loss 17160897
esv1001290 CNV Deletion 20482838
nsv819108 CNV Loss 19587683

Relevant External Links for C14orf159 Gene

HapMap Linkage Disequilibrium report
C14orf159

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf159 Gene

Disorders for C14orf159 Gene

Relevant External Links for C14orf159

Human Genome Epidemiology (HuGE) Navigator
C14orf159

No disorders were found for C14orf159 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C14orf159 Gene

Publications for C14orf159 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. (PMID: 15790807) Cheng J. … Gingeras T.R. (Science 2005) 3

Products for C14orf159 Gene

Sources for C14orf159 Gene

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