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Aliases for C14orf142 Gene

Aliases for C14orf142 Gene

  • Chromosome 14 Open Reading Frame 142 2 3 5
  • PNAS-127 3

External Ids for C14orf142 Gene

Previous GeneCards Identifiers for C14orf142 Gene

  • GC14M087485
  • GC14M091659
  • GC14M092738
  • GC14M093669
  • GC14M073849

Summaries for C14orf142 Gene

GeneCards Summary for C14orf142 Gene

C14orf142 (Chromosome 14 Open Reading Frame 142) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf142 Gene

Genomics for C14orf142 Gene

Regulatory Elements for C14orf142 Gene

Promoters for C14orf142 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C14orf142 on UCSC Golden Path with GeneCards custom track

Genomic Location for C14orf142 Gene

93,202,892 bp from pter
93,207,114 bp from pter
4,223 bases
Minus strand

Genomic View for C14orf142 Gene

Genes around C14orf142 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf142 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf142 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf142 Gene

Proteins for C14orf142 Gene

  • Protein details for C14orf142 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C14orf142
    Protein Accession:
    Secondary Accessions:
    • Q0D2N1
    • Q0P6C4
    • Q3B7W5

    Protein attributes for C14orf142 Gene

    100 amino acids
    Molecular mass:
    10859 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAK07544.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};

neXtProt entry for C14orf142 Gene

Proteomics data for C14orf142 Gene at MOPED

Post-translational modifications for C14orf142 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C14orf142 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf142 Gene

Domains & Families for C14orf142 Gene

Protein Domains for C14orf142 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf142: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf142 Gene

Function for C14orf142 Gene

Phenotypes for C14orf142 Gene

genes like me logo Genes that share phenotypes with C14orf142: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf142 Gene

Localization for C14orf142 Gene

Subcellular locations from

Jensen Localization Image for C14orf142 Gene COMPARTMENTS Subcellular localization image for C14orf142 gene
Compartment Confidence
cytosol 3
nucleus 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C14orf142 Gene

Pathways & Interactions for C14orf142 Gene

SuperPathways for C14orf142 Gene

No Data Available

Interacting Proteins for C14orf142 Gene

Gene Ontology (GO) - Biological Process for C14orf142 Gene


No data available for Pathways by source and SIGNOR curated interactions for C14orf142 Gene

Drugs & Compounds for C14orf142 Gene

No Compound Related Data Available

Transcripts for C14orf142 Gene

mRNA/cDNA for C14orf142 Gene

Unigene Clusters for C14orf142 Gene

Chromosome 14 open reading frame 142:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf142 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b
SP2: -

Relevant External Links for C14orf142 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C14orf142 Gene

mRNA expression in normal human tissues for C14orf142 Gene

Protein differential expression in normal tissues from HIPED for C14orf142 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (19.5) and NK cells (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C14orf142 Gene

SOURCE GeneReport for Unigene cluster for C14orf142 Gene Hs.20142

genes like me logo Genes that share expression patterns with C14orf142: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C14orf142 Gene

Orthologs for C14orf142 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C14orf142 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C21H14orf142 35
  • 84.67 (n)
  • 76 (a)
C21H14orf142 36
  • 76 (a)
(Canis familiaris)
Mammalia C8H14orf142 35
  • 85.67 (n)
  • 77 (a)
C14orf142 36
  • 77 (a)
(Mus musculus)
Mammalia AK010878 35
  • 77.89 (n)
  • 65.31 (a)
AK010878 16
AK010878 36
  • 65 (a)
Gm20604 36
  • 55 (a)
RP24-234J3.4 36
  • 52 (a)
(Pan troglodytes)
Mammalia C14H14orf142 35
  • 100 (n)
  • 100 (a)
C14orf142 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC100233176 35
  • 71.82 (n)
  • 55.67 (a)
(Monodelphis domestica)
Mammalia C14orf142 36
  • 38 (a)
Species with no ortholog for C14orf142:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf142 Gene

Gene Tree for C14orf142 (if available)
Gene Tree for C14orf142 (if available)

Paralogs for C14orf142 Gene

No data available for Paralogs for C14orf142 Gene

Variants for C14orf142 Gene

Sequence variations from dbSNP and Humsavar for C14orf142 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs15418 -- 93,202,999(+) TGCAG(A/G)TTGTT utr-variant-3-prime
rs2532897 -- 93,203,937(+) TTTAA(A/T)ATCTT intron-variant
rs35150499 -- 93,204,433(+) CTCAG(-/C)CTTCG intron-variant
rs36065190 -- 93,202,581(+) AAAAA(-/A)GAAAA downstream-variant-500B
rs34298427 -- 93,203,584(+) AGAAC(-/A)AACAC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C14orf142 Gene

Variant ID Type Subtype PubMed ID
nsv902205 CNV Loss 21882294

Variation tolerance for C14orf142 Gene

Residual Variation Intolerance Score: 77.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.36; 8.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf142 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf142 Gene

Disorders for C14orf142 Gene

Relevant External Links for C14orf142

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C14orf142 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf142 Gene

Publications for C14orf142 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PMID: 23455922) Varjosalo M. … Superti-Furga G. (Nat. Methods 2013) 3
  4. A high-throughput approach for measuring temporal changes in the interactome. (PMID: 22863883) Kristensen A.R. … Foster L.J. (Nat. Methods 2012) 3
  5. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. (PMID: 22912744) Costessi A. … Stunnenberg H.G. (PLoS ONE 2012) 3

Products for C14orf142 Gene

Sources for C14orf142 Gene

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