Aliases for C14orf132 Gene
Aliases for C14orf132 Gene
External Ids for C14orf132 Gene
- HGNC: 20346
- Entrez Gene: 56967
- Ensembl: ENSG00000227051
- UniProtKB: Q9NPU4
Previous HGNC Symbols for C14orf132 Gene
- C14orf88
Previous GeneCards Identifiers for C14orf132 Gene
- GC14P090373
- GC14P094546
- GC14P094495
- GC14P095575
- GC14P096505
- GC14P076690
Summaries for C14orf132 Gene
GeneCards Summary for C14orf132 Gene
C14orf132 (Chromosome 14 Open Reading Frame 132) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf132 Gene
Genomics for C14orf132 Gene
Regulatory Elements for C14orf132 Gene
Enhancers for C14orf132 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH14G096052 | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 8.4 | +14.9 | 14888 | 2.6 | INSM2 KLF17 EBF1 ZIC2 ZNF2 ZFHX2 GLIS2 POLR2A ZBTB48 ZNF366 | C14orf132 BDKRB2 |
| GH14G096100 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 5.2 | +64.9 | 64913 | 7.3 | SIN3A ZNF2 YY1 ZNF121 ZNF143 FOS ZNF263 ZHX2 REST ZNF592 | BDKRB2 C14orf132 BDKRB1 |
| GH14G096089 | 1.3 | Ensembl ENCODE dbSUPER | 6.6 | +52.1 | 52134 | 3.6 | CTCF FEZF1 ZIC2 RAD21 POLR2A ZBTB48 EGR1 FOS ZNF600 PRDM10 | C14orf132 BDKRB2 |
| GH14G096001 | 0.8 | ENCODE | 9.4 | -37.1 | -37103 | 1.2 | CTCF TFAP4 SAP130 ZIC2 RAD21 ZNF644 RARA GATA3 GATA4 POLR2A | C14orf132 ENSG00000271358 GC14P095978 |
| GH14G096038 | 0.9 | ENCODE | 8 | +0.5 | 454 | 2.1 | FUS ZSCAN4 SIN3A THRB CHAMP1 ZNF366 SCRT2 PCBP1 EGR2 ZNF263 | SNHG10 SCARNA13 C14orf132 BDKRB2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around C14orf132 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the C14orf132 gene promoter:
Regulatory Element Products
Genomic Location for C14orf132 Gene
- Chromosome:
- 14
- Start:
- 96,039,324 bp from pter
- End:
- 96,093,971 bp from pter
- Size:
- 54,648 bases
- Orientation:
- Plus strand
Genomic View for C14orf132 Gene
Genes around C14orf132 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.2 by Ensembl
- 14q32.2 by Entrez Gene
- 14q32.2 by HGNC
C14orf132 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for C14orf132 Gene
Proteins for C14orf132 Gene
-
Protein details for C14orf132 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NPU4-CN132_HUMAN
- Recommended name:
- Uncharacterized protein C14orf132
- Protein Accession:
- Q9NPU4
- B2R7K5
Protein attributes for C14orf132 Gene
- Size:
- 83 amino acids
- Molecular mass:
- 8830 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAG35852.1; Type=Erroneous translation; Evidence={ECO:0000305}; Sequence=CAB99085.1; Type=Erroneous translation; Evidence={ECO:0000305}; Sequence=EAW81627.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Post-translational modifications for C14orf132 Gene
No Post-translational modifications
Other Protein References for C14orf132 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for C14orf132
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C14orf132
- Origene Custom Protein Services for C14orf132
- Search GeneTex for Proteins for C14orf132
Assay Products
No data available for DME Specific Peptides for C14orf132 Gene
Domains & Families for C14orf132 Gene
Protein Domains for C14orf132 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf132 Gene
Function for C14orf132 Gene
Phenotypes for C14orf132 Gene
- GenomeRNAi human phenotypes for C14orf132:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for C14orf132
-
- Search ViGene Biosciences for C14orf132
CRISPR Products
- Browse CRISPR knockouts for C14orf132
-
Santa Cruz Biotechnology (SCBT) CRISPR for C14orf132
- GenScript: Design CRISPR guide RNA sequences for C14orf132
miRNA Products
- Search ViGene Biosciences for C14orf132
Inhibitory RNA Products
- Origene RNAi and shRNA products in human, mouse, rat for C14orf132
- Browse OriGene Inhibitory RNA Products For C14orf132
- Search ViGene Biosciences for C14orf132
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C14orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C14orf132
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C14orf132 Gene
Localization for C14orf132 Gene
Subcellular locations from UniProtKB/Swiss-Prot for C14orf132 Gene
- Membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016021 | integral component of membrane | IEA | -- |
Transcripts for C14orf132 Gene
mRNA/cDNA for C14orf132 Gene
- (6) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (174) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for C14orf132 Gene
- Chromosome 14 open reading frame 132:
- Representative Sequences:
CRISPR Products
- Browse CRISPR knockouts for C14orf132
-
Santa Cruz Biotechnology (SCBT) CRISPR for C14orf132
- GenScript: Design CRISPR guide RNA sequences for C14orf132
miRNA Products
- Search ViGene Biosciences for C14orf132
Inhibitory RNA Products
- Origene RNAi and shRNA products in human, mouse, rat for C14orf132
- Browse OriGene Inhibitory RNA Products For C14orf132
- Search ViGene Biosciences for C14orf132
Clone Products
- VectorBuilder custom plasmid, inducible vectors for C14orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C14orf132
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for C14orf132 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Spinal Cord (Nervous System)
mRNA differential expression in normal tissues according to GTEx for C14orf132 Gene
This gene is overexpressed in Brain - Cerebellum (x4.7) and Brain - Cerebellar Hemisphere (x4.5).
NURSA nuclear receptor signaling pathways regulating expression of C14orf132 Gene:
C14orf132SOURCE GeneReport for Unigene cluster for C14orf132 Gene:
Hs.6434Evidence on tissue expression from TISSUES for C14orf132 Gene
- Nervous system(5)
Primer Products
-
OriGene qPCR primer pairs for C14orf132
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C14orf132 Gene
Orthologs for C14orf132 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC743753 34 |
|
||
| cow (Bos Taurus) |
Mammalia | C21H14orf132 34 |
|
- Species where no ortholog for C14orf132 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for C14orf132 Gene
No data available for Paralogs for C14orf132 Gene
Variants for C14orf132 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000000137 | -- | 96,052,362(+) | GGGGC(A/G)TTGGA | intron-variant | |
| rs1000021106 | -- | 96,044,005(+) | CAGCC(A/G)GCAAA | intron-variant | |
| rs1000129585 | -- | 96,046,349(+) | CCGGG(A/G)CTGCC | intron-variant | |
| rs1000177444 | -- | 96,083,554(+) | GATGA(A/C/G)AGAGA | intron-variant | |
| rs1000186271 | -- | 96,077,055(+) | GCTTT(A/G)TGACC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv24297 | CNV | loss | 19812545 |
| esv2657868 | CNV | deletion | 23128226 |
| esv3635413 | CNV | loss | 21293372 |
| nsv1046191 | CNV | gain | 25217958 |
| nsv1046685 | CNV | loss | 25217958 |
| nsv1131161 | CNV | deletion | 24896259 |
| nsv1415 | CNV | insertion | 18451855 |
| nsv520884 | CNV | loss | 19592680 |
| nsv832866 | CNV | gain | 17160897 |
Gene Damage Index Score:
0.36;
7.98% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for C14orf132 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- C14orf132
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf132 Gene
Disorders for C14orf132 Gene
Relevant External Links for C14orf132
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- C14orf132
No disorders were found for C14orf132 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf132 Gene
Publications for C14orf132 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PMID: 21697133) Oshikawa M. … Kato S. (Invest. Ophthalmol. Vis. Sci. 2011) 3 64
- The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 64
Products for C14orf132 Gene
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- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for C14orf132
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- Origene shRNA and RNAi products in human, mouse, rat for C14orf132
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- OriGene qPCR primer pairs for C14orf132
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for C14orf132 in any vector
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- GenScript: Design CRISPR guide RNA sequences for C14orf132
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for C14orf132
- VectorBuilder custom plasmid, inducible vectors for C14orf132
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for C14orf132
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for C14orf132 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
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- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
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- (127) Disease Ontology
- (128) Genetics Home Reference
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- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
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- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer