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Aliases for C14orf132 Gene

Aliases for C14orf132 Gene

  • Chromosome 14 Open Reading Frame 132 2 3 5
  • C14orf88 3 4
  • Putative Uncharacterized Protein C14orf132 3
  • Chromosome 14 Open Reading Frame 88 2
  • Uncharacterized Protein C14orf132 3

External Ids for C14orf132 Gene

Previous HGNC Symbols for C14orf132 Gene

  • C14orf88

Previous GeneCards Identifiers for C14orf132 Gene

  • GC14P090373
  • GC14P094546
  • GC14P094495
  • GC14P095575
  • GC14P096505
  • GC14P076690

Summaries for C14orf132 Gene

GeneCards Summary for C14orf132 Gene

C14orf132 (Chromosome 14 Open Reading Frame 132) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf132 Gene

Genomics for C14orf132 Gene

Regulatory Elements for C14orf132 Gene

Enhancers for C14orf132 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F096001 0.5 ENCODE 9.3 -37.1 -37103 1.2 CTCF TFAP4 SAP130 ZIC2 ZNF644 RAD21 RARA GATA3 GATA4 POLR2A C14orf132 ENSG00000271358 GC14P095978
GH14F095993 0.6 ENCODE 8.8 -45.3 -45279 1.1 ZNF263 CTCF ZNF654 RFX1 TRIM22 REST RAD21 SCRT2 SMC3 C14orf132 GC14P095978 ENSG00000271358
GH14F096052 1.4 FANTOM5 Ensembl ENCODE 8.4 +14.9 14888 2.6 INSM2 KLF17 EBF1 ZIC2 ZNF2 ZFHX2 GLIS2 ZBTB48 POLR2A ZNF366 C14orf132 BDKRB2
GH14F096038 0.5 ENCODE 8 +0.5 454 2.1 SIN3A THRB CHAMP1 ZNF366 SCRT2 EGR2 ZNF263 ZNF202 SP3 REST SCARNA13 SNHG10 ATG2B C14orf132 BDKRB2
GH14F095978 0.2 ENCODE 7.2 -59.5 -59504 2.1 CTCF ATF1 CBX3 TAL1 TEAD4 CEBPG RAD21 GATA2 NCOR1 TRIM24 C14orf132 GC14P095978 ENSG00000271358
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C14orf132 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf132 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000181415 376 1801 THRB CHAMP1 ZNF366 SCRT2 EGR2 ZNF263 ZNF202 SP3 REST TBX21

Genomic Location for C14orf132 Gene

Chromosome:
14
Start:
96,039,324 bp from pter
End:
96,093,971 bp from pter
Size:
54,648 bases
Orientation:
Plus strand

Genomic View for C14orf132 Gene

Genes around C14orf132 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf132 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf132 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf132 Gene

Proteins for C14orf132 Gene

  • Protein details for C14orf132 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NPU4-CN132_HUMAN
    Recommended name:
    Uncharacterized protein C14orf132
    Protein Accession:
    Q9NPU4
    Secondary Accessions:
    • B2R7K5

    Protein attributes for C14orf132 Gene

    Size:
    83 amino acids
    Molecular mass:
    8830 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAG35852.1; Type=Erroneous translation; Evidence={ECO:0000305}; Sequence=CAB99085.1; Type=Erroneous translation; Evidence={ECO:0000305}; Sequence=EAW81627.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for C14orf132 Gene

Post-translational modifications for C14orf132 Gene

No Post-translational modifications

Other Protein References for C14orf132 Gene

No data available for DME Specific Peptides for C14orf132 Gene

Domains & Families for C14orf132 Gene

Protein Domains for C14orf132 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf132: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf132 Gene

Function for C14orf132 Gene

Phenotypes for C14orf132 Gene

GenomeRNAi human phenotypes for C14orf132:
genes like me logo Genes that share phenotypes with C14orf132: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C14orf132 Gene

Localization for C14orf132 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf132 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf132 Gene COMPARTMENTS Subcellular localization image for C14orf132 gene
Compartment Confidence
plasma membrane 3
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C14orf132 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C14orf132: view

Pathways & Interactions for C14orf132 Gene

SuperPathways for C14orf132 Gene

No Data Available

Interacting Proteins for C14orf132 Gene

Gene Ontology (GO) - Biological Process for C14orf132 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf132 Gene

Transcripts for C14orf132 Gene

Unigene Clusters for C14orf132 Gene

Chromosome 14 open reading frame 132:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf132 Gene

No ASD Table

Relevant External Links for C14orf132 Gene

GeneLoc Exon Structure for
C14orf132
ECgene alternative splicing isoforms for
C14orf132

Expression for C14orf132 Gene

mRNA expression in normal human tissues for C14orf132 Gene

mRNA differential expression in normal tissues according to GTEx for C14orf132 Gene

This gene is overexpressed in Brain - Cerebellum (x4.7) and Brain - Cerebellar Hemisphere (x4.5).

NURSA nuclear receptor signaling pathways regulating expression of C14orf132 Gene:

C14orf132

SOURCE GeneReport for Unigene cluster for C14orf132 Gene:

Hs.6434
genes like me logo Genes that share expression patterns with C14orf132: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C14orf132 Gene

Orthologs for C14orf132 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C14orf132 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC743753 34
  • 98.83 (n)
cow
(Bos Taurus)
Mammalia C21H14orf132 34
  • 87.55 (n)
Species where no ortholog for C14orf132 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf132 Gene

ENSEMBL:
Gene Tree for C14orf132 (if available)
TreeFam:
Gene Tree for C14orf132 (if available)

Paralogs for C14orf132 Gene

No data available for Paralogs for C14orf132 Gene

Variants for C14orf132 Gene

Sequence variations from dbSNP and Humsavar for C14orf132 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10082 -- 96,093,454(-) GGCAC(A/G)TGGAA intron-variant, utr-variant-3-prime
rs10129806 -- 96,049,625(+) gtata(C/T)atata intron-variant, upstream-variant-2KB
rs10129807 -- 96,049,627(+) atata(C/T)ataca intron-variant, upstream-variant-2KB
rs10129813 -- 96,049,651(+) ATATA(G/T)ATaga intron-variant, upstream-variant-2KB
rs10129814 -- 96,049,653(+) ATATa(G/T)agaga intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C14orf132 Gene

Variant ID Type Subtype PubMed ID
esv24297 CNV loss 19812545
esv2657868 CNV deletion 23128226
esv3635413 CNV loss 21293372
nsv1046191 CNV gain 25217958
nsv1046685 CNV loss 25217958
nsv1131161 CNV deletion 24896259
nsv1415 CNV insertion 18451855
nsv520884 CNV loss 19592680
nsv832866 CNV gain 17160897

Variation tolerance for C14orf132 Gene

Gene Damage Index Score: 0.36; 7.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf132 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C14orf132

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf132 Gene

Disorders for C14orf132 Gene

Relevant External Links for C14orf132

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf132

No disorders were found for C14orf132 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf132 Gene

Publications for C14orf132 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PMID: 21697133) Oshikawa M. … Kato S. (Invest. Ophthalmol. Vis. Sci. 2011) 3 64
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 64

Products for C14orf132 Gene

Sources for C14orf132 Gene

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