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Aliases for C14orf119 Gene

Aliases for C14orf119 Gene

  • Chromosome 14 Open Reading Frame 119 2 3 5

External Ids for C14orf119 Gene

Previous GeneCards Identifiers for C14orf119 Gene

  • GC00U900532
  • GC14P021555
  • GC14P021556
  • GC14P021557
  • GC14P022634
  • GC14P023563
  • GC14P003681
  • GC14P023394
  • GC14P023559
  • GC14P023673
  • GC14P023796
  • GC14P023886

Summaries for C14orf119 Gene

GeneCards Summary for C14orf119 Gene

C14orf119 (Chromosome 14 Open Reading Frame 119) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf119 Gene

Genomics for C14orf119 Gene

Regulatory Elements for C14orf119 Gene

Enhancers for C14orf119 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G022504 2.1 FANTOM5 Ensembl ENCODE dbSUPER 13.5 -556.6 -556578 66.7 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 YBX1 YY1 SLC30A9 ZNF143 MMP14 ABHD4 OXA1L EFS BCL2L2-PABPN1 DAD1 LOC105370399 TRAC C14orf119 OR6J1
GH14G022976 1.9 FANTOM5 ENCODE dbSUPER 13.6 -114.9 -114860 7.6 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF548 PRMT5 HAUS4 LOC102724814 MMP14 PSMB5 C14orf119 CDH24 C14orf93 PSMB11 PABPN1
GH14G022955 1.1 ENCODE 21.7 -138.2 -138161 2.6 HDGF HNRNPUL1 PKNOX1 MLX CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1 HAUS4 C14orf119 AJUBA PSMB5 PSMB11 CDH24 C14orf93 LOC102724814 ACIN1 MIR4707
GH14G024091 1.7 Ensembl ENCODE dbSUPER 11.6 +998.9 998882 6.5 MLX AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 RNA5SP383 KHNYN CARMIL3 C14orf119 NYNRIN DCAF11 NRL TM9SF1 IPO4 IRF9
GH14G023067 1.6 Ensembl ENCODE dbSUPER 12 -24.3 -24303 5.9 HDGF PKNOX1 MLX ARNT ZFP64 WRNIP1 SIN3A ARID4B DMAP1 YBX1 PSMB11 PSMB5 C14orf119 ACIN1 C14orf93 CEBPE AJUBA HAUS4 RNF212B SLC7A8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C14orf119 on UCSC Golden Path with GeneCards custom track

Promoters for C14orf119 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000066689 535 2601 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2

Genomic Location for C14orf119 Gene

Chromosome:
14
Start:
23,094,765 bp from pter
End:
23,100,462 bp from pter
Size:
5,698 bases
Orientation:
Plus strand

Genomic View for C14orf119 Gene

Genes around C14orf119 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C14orf119 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C14orf119 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf119 Gene

Proteins for C14orf119 Gene

  • Protein details for C14orf119 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWQ9-CN119_HUMAN
    Recommended name:
    Uncharacterized protein C14orf119
    Protein Accession:
    Q9NWQ9
    Secondary Accessions:
    • Q6IAA7

    Protein attributes for C14orf119 Gene

    Size:
    140 amino acids
    Molecular mass:
    16009 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf119 Gene

Post-translational modifications for C14orf119 Gene

  • Ubiquitination at Lys128 and Lys139
  • Modification sites at PhosphoSitePlus

Other Protein References for C14orf119 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf119 Gene

Domains & Families for C14orf119 Gene

Protein Domains for C14orf119 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf119: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf119 Gene

Function for C14orf119 Gene

Phenotypes for C14orf119 Gene

genes like me logo Genes that share phenotypes with C14orf119: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf119 Gene

Localization for C14orf119 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf119 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C14orf119 gene
Compartment Confidence
mitochondrion 5
cytosol 5
extracellular 2
nucleus 2

Gene Ontology (GO) - Cellular Components for C14orf119 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with C14orf119: view

Pathways & Interactions for C14orf119 Gene

SuperPathways for C14orf119 Gene

No Data Available

Interacting Proteins for C14orf119 Gene

Selected Interacting proteins: Q9NWQ9-CN119_HUMAN for C14orf119 Gene via IID

Symbol External ID(s) Details
LRRCC1
XPO1

Gene Ontology (GO) - Biological Process for C14orf119 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf119 Gene

Drugs & Compounds for C14orf119 Gene

No Compound Related Data Available

Transcripts for C14orf119 Gene

mRNA/cDNA for C14orf119 Gene

Unigene Clusters for C14orf119 Gene

Chromosome 14 open reading frame 119:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf119 Gene

No ASD Table

Relevant External Links for C14orf119 Gene

GeneLoc Exon Structure for
C14orf119
ECgene alternative splicing isoforms for
C14orf119

Expression for C14orf119 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C14orf119 Gene

Protein differential expression in normal tissues from HIPED for C14orf119 Gene

This gene is overexpressed in Bone (66.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C14orf119 Gene



Protein tissue co-expression partners for C14orf119 Gene

NURSA nuclear receptor signaling pathways regulating expression of C14orf119 Gene:

C14orf119

SOURCE GeneReport for Unigene cluster for C14orf119 Gene:

Hs.525238

Evidence on tissue expression from TISSUES for C14orf119 Gene

  • Nervous system(4.7)
  • Intestine(4.3)
  • Lung(4.3)
genes like me logo Genes that share expression patterns with C14orf119: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C14orf119 Gene

Orthologs for C14orf119 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf119 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14orf119 35
  • 100 (a)
OneToOne
C14H14orf119 34
  • 99.76 (n)
dog
(Canis familiaris)
Mammalia C8H14orf119 34
  • 93.73 (n)
-- 35
  • 87 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
cow
(Bos Taurus)
Mammalia C10H14orf119 34
  • 91.74 (n)
C14orf119 35
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700123O20Rik 34 16 35
  • 86.67 (n)
rat
(Rattus norvegicus)
Mammalia RGD1308430 34
  • 86.43 (n)
oppossum
(Monodelphis domestica)
Mammalia C14orf119 35
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf119 35
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C14orf119 35
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c14orf119 34
  • 63 (n)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-14a17.11 34
  • 49.88 (n)
C2H14orf119 35
  • 34 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 44 (a)
OneToOne
Species where no ortholog for C14orf119 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C14orf119 Gene

ENSEMBL:
Gene Tree for C14orf119 (if available)
TreeFam:
Gene Tree for C14orf119 (if available)

Paralogs for C14orf119 Gene

Pseudogenes.org Pseudogenes for C14orf119 Gene

genes like me logo Genes that share paralogs with C14orf119: view

No data available for Paralogs for C14orf119 Gene

Variants for C14orf119 Gene

Sequence variations from dbSNP and Humsavar for C14orf119 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000883684 -- 23,095,723(+) CTGCC(C/T)TCTGT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1001705922 -- 23,096,230(+) AGTGG(C/G)AAGGT intron-variant, upstream-variant-2KB
rs1001777952 -- 23,094,476(+) TAAAG(A/C/G)TCTCT intron-variant, upstream-variant-2KB
rs1002044926 -- 23,098,208(+) TCACT(A/G)ACCAG intron-variant, utr-variant-3-prime
rs1002110801 -- 23,096,605(+) GGGTC(C/T)CTCCA intron-variant, upstream-variant-2KB

Variation tolerance for C14orf119 Gene

Residual Variation Intolerance Score: 74.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.43; 28.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf119 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C14orf119

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C14orf119 Gene

Disorders for C14orf119 Gene

Relevant External Links for C14orf119

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf119

No disorders were found for C14orf119 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf119 Gene

Publications for C14orf119 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. (PMID: 26598620) Dart A.E. … Wells C.M. (J. Cell Biol. 2015) 3 64
  4. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3 64
  5. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PMID: 22361696) Stadler C. … Lundberg E. (J. Proteomics 2012) 4 64

Products for C14orf119 Gene

Sources for C14orf119 Gene

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