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Aliases for C14orf119 Gene

Aliases for C14orf119 Gene

  • Chromosome 14 Open Reading Frame 119 2 3

External Ids for C14orf119 Gene

Previous GeneCards Identifiers for C14orf119 Gene

  • GC00U900532
  • GC14P021555
  • GC14P021556
  • GC14P021557
  • GC14P022634
  • GC14P023563
  • GC14P003681
  • GC14P023394

Summaries for C14orf119 Gene

GeneCards Summary for C14orf119 Gene

C14orf119 (Chromosome 14 Open Reading Frame 119) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf119 Gene

Genomics for C14orf119 Gene

Regulatory Elements for C14orf119 Gene

Genomic Location for C14orf119 Gene

Chromosome:
14
Start:
23,094,765 bp from pter
End:
23,100,462 bp from pter
Size:
5,698 bases
Orientation:
Plus strand

Genomic View for C14orf119 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf119 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf119 Gene

Proteins for C14orf119 Gene

  • Protein details for C14orf119 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWQ9-CN119_HUMAN
    Recommended name:
    Uncharacterized protein C14orf119
    Protein Accession:
    Q9NWQ9
    Secondary Accessions:
    • Q6IAA7

    Protein attributes for C14orf119 Gene

    Size:
    140 amino acids
    Molecular mass:
    16009 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf119 Gene

Proteomics data for C14orf119 Gene at MOPED

Post-translational modifications for C14orf119 Gene

  • Ubiquitination at Lys 128 and Lys 139
  • Modification sites at PhosphoSitePlus

Other Protein References for C14orf119 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C14orf119 Gene

Domains & Families for C14orf119 Gene

Protein Domains for C14orf119 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf119: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C14orf119 Gene

Function for C14orf119 Gene

Phenotypes for C14orf119 Gene

genes like me logo Genes that share phenotypes with C14orf119: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C14orf119 Gene

Localization for C14orf119 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C14orf119 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf119 Gene COMPARTMENTS Subcellular localization image for C14orf119 gene
Compartment Confidence
mitochondrion 3
cytosol 2

Gene Ontology (GO) - Cellular Components for C14orf119 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with C14orf119: view

Pathways & Interactions for C14orf119 Gene

SuperPathways for C14orf119 Gene

No Data Available

Interacting Proteins for C14orf119 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000322238%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000353538%0d%0a
Selected Interacting proteins: Q9NWQ9-CN119_HUMAN ENSP00000322238 for C14orf119 Gene via MINT I2D STRING

Gene Ontology (GO) - Biological Process for C14orf119 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C14orf119 Gene

Drugs & Compounds for C14orf119 Gene

No Compound Related Data Available

Transcripts for C14orf119 Gene

mRNA/cDNA for C14orf119 Gene

Unigene Clusters for C14orf119 Gene

Chromosome 14 open reading frame 119:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C14orf119

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf119 Gene

No ASD Table

Relevant External Links for C14orf119 Gene

GeneLoc Exon Structure for
C14orf119
ECgene alternative splicing isoforms for
C14orf119

Expression for C14orf119 Gene

mRNA expression in normal human tissues for C14orf119 Gene

Protein differential expression in normal tissues from HIPED for C14orf119 Gene

This gene is overexpressed in Bone (66.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C14orf119 Gene



SOURCE GeneReport for Unigene cluster for C14orf119 Gene Hs.525238

genes like me logo Genes that share expression patterns with C14orf119: view

Protein tissue co-expression partners for C14orf119 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C14orf119 Gene

Orthologs for C14orf119 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf119 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C10H14orf119 35
  • 91.74 (n)
  • 89.26 (a)
C14orf119 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C8H14orf119 35
  • 93.73 (n)
  • 89.74 (a)
-- 36
  • 82 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 87 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 1700123O20Rik 35
  • 86.67 (n)
  • 84.29 (a)
1700123O20Rik 16
1700123O20Rik 36
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf119 35
  • 99.76 (n)
  • 100 (a)
C14orf119 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1308430 35
  • 86.43 (n)
  • 84.29 (a)
oppossum
(Monodelphis domestica)
Mammalia C14orf119 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf119 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C14orf119 36
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c14orf119 35
  • 63 (n)
  • 61.47 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-14a17.11 35
  • 49.88 (n)
  • 49.64 (a)
C2H14orf119 36
  • 34 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
OneToOne
Species with no ortholog for C14orf119:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C14orf119 Gene

ENSEMBL:
Gene Tree for C14orf119 (if available)
TreeFam:
Gene Tree for C14orf119 (if available)

Paralogs for C14orf119 Gene

Pseudogenes.org Pseudogenes for C14orf119 Gene

genes like me logo Genes that share paralogs with C14orf119: view

No data available for Paralogs for C14orf119 Gene

Variants for C14orf119 Gene

Sequence variations from dbSNP and Humsavar for C14orf119 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs6736 -- 23,098,565(+) AGTTT(A/T)CCCAG utr-variant-3-prime
rs12400 -- 23,098,160(+) TGTGT(C/T)GCCTA utr-variant-3-prime
rs14669 -- 23,098,520(-) TGATA(G/T)GAGTG utr-variant-3-prime
rs1059356 -- 23,098,234(+) TTCAA(C/T)ATTAA utr-variant-3-prime
rs1059379 -- 23,098,551(+) TACGC(A/G)AAACC utr-variant-3-prime

Variation tolerance for C14orf119 Gene

Residual Variation Intolerance Score: 74.25% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.43; 28.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C14orf119 Gene

HapMap Linkage Disequilibrium report
C14orf119

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C14orf119 Gene

Disorders for C14orf119 Gene

Relevant External Links for C14orf119

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C14orf119
genes like me logo Genes that share disorders with C14orf119: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C14orf119 Gene

Publications for C14orf119 Gene

  1. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. (PMID: 22361696) Stadler C. … Lundberg E. (J. Proteomics 2012) 67
  2. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  5. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 67

Products for C14orf119 Gene

Sources for C14orf119 Gene

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