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Aliases for C14orf105 Gene

Aliases for C14orf105 Gene

  • Chromosome 14 Open Reading Frame 105 2 3

External Ids for C14orf105 Gene

Previous GeneCards Identifiers for C14orf105 Gene

  • GC14M051732
  • GC14M055926
  • GC14M057006
  • GC14M057936
  • GC14M038101

Summaries for C14orf105 Gene

GeneCards Summary for C14orf105 Gene

C14orf105 (Chromosome 14 Open Reading Frame 105) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C14orf105 Gene

Genomics for C14orf105 Gene

Regulatory Elements for C14orf105 Gene

Genomic Location for C14orf105 Gene

Start:
57,469,300 bp from pter
End:
57,493,867 bp from pter
Size:
24,568 bases
Orientation:
Minus strand

Genomic View for C14orf105 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C14orf105 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C14orf105 Gene

Proteins for C14orf105 Gene

  • Protein details for C14orf105 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NVL8-CN105_HUMAN
    Recommended name:
    Uncharacterized protein C14orf105
    Protein Accession:
    Q9NVL8
    Secondary Accessions:
    • Q53G04

    Protein attributes for C14orf105 Gene

    Size:
    296 amino acids
    Molecular mass:
    34690 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C14orf105 Gene

Proteomics data for C14orf105 Gene at MOPED

Post-translational modifications for C14orf105 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C14orf105 Gene

Domains for C14orf105 Gene

Protein Domains for C14orf105 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C14orf105 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C14orf105: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C14orf105 Gene

Function for C14orf105 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C14orf105 Gene

Localization for C14orf105 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C14orf105 Gene COMPARTMENTS Subcellular localization image for C14orf105 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C14orf105 Gene

Pathways for C14orf105 Gene

SuperPathways for C14orf105 Gene

No Data Available

Interacting Proteins for C14orf105 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000216445%0d%0a9606.ENSP00000358363%0d%0a9606.ENSP00000340995%0d%0a
Selected Interacting proteins: ENSP00000216445 for C14orf105 Gene via STRING

Gene Ontology (GO) - Biological Process for C14orf105 Gene

None

No data available for Pathways by source for C14orf105 Gene

Transcripts for C14orf105 Gene

Unigene Clusters for C14orf105 Gene

Chromosome 14 open reading frame 105:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C14orf105 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6
SP1: - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: - -
SP6:

Relevant External Links for C14orf105 Gene

GeneLoc Exon Structure for
C14orf105
ECgene alternative splicing isoforms for
C14orf105

Expression for C14orf105 Gene

mRNA expression in normal human tissues for C14orf105 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C14orf105 Gene

This gene is overexpressed in Kidney - Cortex (22.4), Liver (11.9), and Pancreas (10.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for C14orf105 Gene

SOURCE GeneReport for Unigene cluster for C14orf105 Gene Hs.659706

genes like me logo Genes that share expressions with C14orf105: view

No data available for mRNA Expression by UniProt/SwissProt for C14orf105 Gene

Orthologs for C14orf105 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C14orf105 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf105 35
  • 99.32 (n)
  • 98.65 (a)
C14orf105 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C10H14orf105 35
  • 85.94 (n)
  • 76.53 (a)
C14orf105 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C14orf105 36
  • 69 (a)
OneToOne
C8H14orf105 35
  • 86.23 (n)
  • 78.84 (a)
mouse
(Mus musculus)
Mammalia 1700011H14Rik 35
  • 78.31 (n)
  • 64.04 (a)
1700011H14Rik 16
1700011H14Rik 36
  • 63 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C14orf105 36
  • 45 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C14orf105 36
  • 38 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102556129 35
  • 78.22 (n)
  • 67.33 (a)
chicken
(Gallus gallus)
Aves C14orf105 36
  • 32 (a)
OneToOne
C5H14ORF105 35
  • 53.91 (n)
  • 42.6 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496610 35
  • 53.66 (n)
  • 42.68 (a)
Species with no ortholog for C14orf105:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C14orf105 Gene

ENSEMBL:
Gene Tree for C14orf105 (if available)
TreeFam:
Gene Tree for C14orf105 (if available)

Paralogs for C14orf105 Gene

genes like me logo Genes that share paralogs with C14orf105: view

No data available for Paralogs for C14orf105 Gene

Variants for C14orf105 Gene

Sequence variations from dbSNP and Humsavar for C14orf105 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1564 -- 57,478,583(-) TTGGC(A/G)AAGTC intron-variant, utr-variant-3-prime
rs268814 -- 57,493,326(-) CATCA(A/G)TTGAA intron-variant
rs268815 -- 57,493,426(-) TATCT(C/G)ACTGT intron-variant
rs268816 -- 57,493,434(-) AATAG(A/G)TTTAT intron-variant
rs949993 -- 57,479,847(-) tccat(G/T)tggtc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C14orf105 Gene

Variant ID Type Subtype PubMed ID
nsv832806 CNV Loss 17160897

Relevant External Links for C14orf105 Gene

HapMap Linkage Disequilibrium report
C14orf105
Human Gene Mutation Database (HGMD)
C14orf105

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C14orf105 Gene

Disorders for C14orf105 Gene

Relevant External Links for C14orf105

Human Genome Epidemiology (HuGE) Navigator
C14orf105
genes like me logo Genes that share disorders with C14orf105: view

No data available for UniProtKB/Swiss-Prot for C14orf105 Gene

Publications for C14orf105 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for C14orf105 Gene

Sources for C14orf105 Gene

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