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Aliases for C12orf80 Gene

Aliases for C12orf80 Gene

  • Chromosome 12 Open Reading Frame 80 2 3 5

External Ids for C12orf80 Gene

Previous GeneCards Identifiers for C12orf80 Gene

  • GC12M052600

Summaries for C12orf80 Gene

GeneCards Summary for C12orf80 Gene

C12orf80 (Chromosome 12 Open Reading Frame 80) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf80 Gene

Genomics for C12orf80 Gene

Regulatory Elements for C12orf80 Gene

Enhancers for C12orf80 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G052196 2 FANTOM5 Ensembl ENCODE dbSUPER 7.3 +5.7 5651 22.5 HDGF PKNOX1 SIN3A ZBTB7B ZNF766 ZNF207 ZNF143 ZNF548 FOS DEK KRT7 ZNF740 HNRNPA3P10 KRT86 KRT87P KRT81 KRT83 LOC283335 KRT84 KRT6C
GH12G052180 1.9 FANTOM5 Ensembl ENCODE dbSUPER 6.8 +25.1 25119 15.1 PKNOX1 SIN3A FEZF1 ZNF2 ZBTB7B ZNF416 FOS ZNF263 SP3 REST KRT80 ZNF740 KRT7 SPRYD3 C12orf80 NR4A1 FIGNL2 ACVRL1 ATG101 GRASP
GH12G052221 1.3 Ensembl ENCODE dbSUPER 0.4 -8.5 -8453 1.6 FOXA2 RB1 SIN3A RAD21 SMARCC2 FOS EGR2 SMARCC1 USF2 CEBPB KRT7 ZNF740 KRT86 KRT87P KRT83 KRT81 C12orf80
GH12G052229 0.7 ENCODE dbSUPER 0.4 -15.0 -14969 0.2 GATA3 FOS CUX1 KRT77 KRT7 C12orf80
GH12G052225 0.4 dbSUPER 0.4 -12.2 -12244 0.8 GLIS1 ZIC2 KRT80 KRT86 KRT87P KRT83 KRT7 KRT81 KRT77 C12orf80
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C12orf80 on UCSC Golden Path with GeneCards custom track

Genomic Location for C12orf80 Gene

Chromosome:
12
Start:
52,205,556 bp from pter
End:
52,213,583 bp from pter
Size:
8,028 bases
Orientation:
Minus strand

Genomic View for C12orf80 Gene

Genes around C12orf80 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C12orf80 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C12orf80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf80 Gene

Proteins for C12orf80 Gene

Post-translational modifications for C12orf80 Gene

No Post-translational modifications

Other Protein References for C12orf80 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C12orf80 Gene

Domains & Families for C12orf80 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C12orf80 Gene

Function for C12orf80 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf80 Gene

Localization for C12orf80 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C12orf80 Gene

Pathways & Interactions for C12orf80 Gene

SuperPathways for C12orf80 Gene

No Data Available

Interacting Proteins for C12orf80 Gene

Gene Ontology (GO) - Biological Process for C12orf80 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C12orf80 Gene

Drugs & Compounds for C12orf80 Gene

No Compound Related Data Available

Transcripts for C12orf80 Gene

mRNA/cDNA for C12orf80 Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf80 Gene

No ASD Table

Relevant External Links for C12orf80 Gene

GeneLoc Exon Structure for
C12orf80
ECgene alternative splicing isoforms for
C12orf80

Expression for C12orf80 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C12orf80 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C12orf80 Gene

This gene is overexpressed in Testis (x50.1).

NURSA nuclear receptor signaling pathways regulating expression of C12orf80 Gene:

C12orf80
genes like me logo Genes that share expression patterns with C12orf80: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C12orf80 Gene

Orthologs for C12orf80 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C12orf80 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100608471 34
  • 98.37 (n)
Species where no ortholog for C12orf80 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf80 Gene

ENSEMBL:
Gene Tree for C12orf80 (if available)
TreeFam:
Gene Tree for C12orf80 (if available)

Paralogs for C12orf80 Gene

No data available for Paralogs for C12orf80 Gene

Variants for C12orf80 Gene

Sequence variations from dbSNP and Humsavar for C12orf80 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000752252 -- 52,206,131(+) TGGAG(A/G)CTCTC reference, missense
rs1000815060 -- 52,207,358(+) TAATC(A/C)GAAGG intron-variant
rs1001310380 -- 52,205,701(+) TTGGT(C/T)TCTCT utr-variant-3-prime
rs1001655644 -- 52,209,602(+) TGGGG(A/T)CAGAT intron-variant, upstream-variant-2KB
rs1001762750 -- 52,212,505(+) GTTGT(A/G)GCTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C12orf80 Gene

Variant ID Type Subtype PubMed ID
esv2759899 CNV gain 17122850
nsv469381 CNV loss 19166990
nsv558899 CNV loss 21841781
nsv832409 CNV loss 17160897

Relevant External Links for C12orf80 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C12orf80

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for C12orf80 Gene

Disorders for C12orf80 Gene

Relevant External Links for C12orf80

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C12orf80

No disorders were found for C12orf80 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf80 Gene

Publications for C12orf80 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for C12orf80 Gene

Sources for C12orf80 Gene

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