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Aliases for C12orf77 Gene

Aliases for C12orf77 Gene

  • Chromosome 12 Open Reading Frame 77 2 3 5

External Ids for C12orf77 Gene

Previous GeneCards Identifiers for C12orf77 Gene

  • GC12M025038
  • GC12M025146
  • GC12M024916

Summaries for C12orf77 Gene

GeneCards Summary for C12orf77 Gene

C12orf77 (Chromosome 12 Open Reading Frame 77) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf77 Gene

Genomics for C12orf77 Gene

Regulatory Elements for C12orf77 Gene

Enhancers for C12orf77 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F024995 0.8 FANTOM5 Ensembl ENCODE 23.5 +8.8 8817 3.7 TBP PKNOX1 TBL1XR1 SIN3A BMI1 GLI4 ZBTB40 ELK1 CBX5 ZNF143 C12orf77 LRMP LOC645177
GH12F025004 0.4 ENCODE 13 +0.9 941 1.2 SRF TBP MTA2 BMI1 EBF1 TBX21 EP300 RAD51 POLR2A IKZF1 C12orf77 BCAT1 LRMP
GH12F025039 0.4 Ensembl 11.4 -33.0 -32954 0.5 LRMP C12orf77 CENPUP2
GH12F025038 0.2 Ensembl 11.4 -32.5 -32498 0.2 C12orf77 CENPUP2
GH12F024951 1.2 FANTOM5 ENCODE 6.2 +54.2 54185 1.8 ATF1 ARNT ZNF207 NCOA1 JUNB TBX21 MBD2 SMARCA4 PBX2 NBN LRMP BCAT1 C12orf77 KRAS BRI3P2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C12orf77 on UCSC Golden Path with GeneCards custom track

Genomic Location for C12orf77 Gene

Chromosome:
12
Start:
24,993,424 bp from pter
End:
25,006,403 bp from pter
Size:
12,980 bases
Orientation:
Minus strand

Genomic View for C12orf77 Gene

Genes around C12orf77 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C12orf77 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C12orf77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf77 Gene

Proteins for C12orf77 Gene

  • Protein details for C12orf77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JDV5-CL097_HUMAN
    Recommended name:
    Putative uncharacterized protein C12orf77
    Protein Accession:
    C9JDV5

    Protein attributes for C12orf77 Gene

    Size:
    145 amino acids
    Molecular mass:
    16178 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C12orf77 Gene

Post-translational modifications for C12orf77 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf77 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C12orf77 Gene

Domains & Families for C12orf77 Gene

Protein Domains for C12orf77 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C12orf77: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C12orf77 Gene

Function for C12orf77 Gene

Phenotypes for C12orf77 Gene

GenomeRNAi human phenotypes for C12orf77:
genes like me logo Genes that share phenotypes with C12orf77: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf77 Gene

Localization for C12orf77 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C12orf77 Gene COMPARTMENTS Subcellular localization image for C12orf77 gene
Compartment Confidence
extracellular 2
cytosol 1
nucleus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C12orf77 Gene

Pathways & Interactions for C12orf77 Gene

SuperPathways for C12orf77 Gene

No Data Available

Interacting Proteins for C12orf77 Gene

Gene Ontology (GO) - Biological Process for C12orf77 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C12orf77 Gene

Transcripts for C12orf77 Gene

mRNA/cDNA for C12orf77 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(19) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C12orf77 Gene

Chromosome 12 open reading frame 77:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf77 Gene

No ASD Table

Relevant External Links for C12orf77 Gene

GeneLoc Exon Structure for
C12orf77
ECgene alternative splicing isoforms for
C12orf77

Expression for C12orf77 Gene

mRNA expression in normal human tissues for C12orf77 Gene

NURSA nuclear receptor signaling pathways regulating expression of C12orf77 Gene:

C12orf77

SOURCE GeneReport for Unigene cluster for C12orf77 Gene:

Hs.434453
genes like me logo Genes that share expression patterns with C12orf77: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C12orf77 Gene

Orthologs for C12orf77 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C12orf77 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf77 34
  • 98.16 (n)
C12orf77 35
  • 97 (a)
OneToOne
Species where no ortholog for C12orf77 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf77 Gene

ENSEMBL:
Gene Tree for C12orf77 (if available)
TreeFam:
Gene Tree for C12orf77 (if available)

Paralogs for C12orf77 Gene

No data available for Paralogs for C12orf77 Gene

Variants for C12orf77 Gene

Sequence variations from dbSNP and Humsavar for C12orf77 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10505956 -- 24,997,578(+) TCAGA(C/T)GGTTC upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime
rs11047745 -- 24,994,140(+) TGCAT(A/C)TTGGT utr-variant-3-prime
rs11047746 -- 24,994,424(+) gaggc(C/T)gaggc intron-variant
rs11047747 -- 24,995,076(+) ttttt(A/T)atttt intron-variant
rs11047748 -- 24,995,077(+) ttttt(A/T)ttttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C12orf77 Gene

Variant ID Type Subtype PubMed ID
dgv2412n54 CNV gain 21841781
esv2422312 CNV duplication 17116639
nsv469169 CNV gain 19166990
nsv469173 CNV gain 19166990
nsv469174 CNV loss 19166990
nsv557775 CNV gain 21841781
nsv557795 CNV loss 21841781

Variation tolerance for C12orf77 Gene

Residual Variation Intolerance Score: 72.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.11; 38.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C12orf77 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C12orf77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf77 Gene

Disorders for C12orf77 Gene

Relevant External Links for C12orf77

Genetic Association Database (GAD)
C12orf77
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C12orf77

No disorders were found for C12orf77 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf77 Gene

Publications for C12orf77 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  2. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 46 64
  3. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C12orf77 Gene

Sources for C12orf77 Gene

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