C12orf76 Gene
protein-coding GIFtS: 36
GCID: GC12M110478 (predicted)
|
|
chromosome 12 open reading frame 76
| |
Aliases
for C12orf76 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 12 Open Reading Frame 761 2 | | FLJ401421 | | Uncharacterized Protein C12orf762 |
Export aliases for C12orf76 gene to outside databasesPrevious GC identifers: GC12M108963 GC12M107494 |
Summaries
for C12orf76 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C12orf76 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C12orf76 gene promoter:
USF1 NF-1 p53 USF2 USF-1:USF-2 LUN-1 POU3F2 USF-1 Zic3 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for C12orf76
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C12orf76 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.11 Ensembl cytogenetic band: 12q24.11 HGNC cytogenetic band: 12q24.11C12orf76 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M110478: view genomic region
(about GC identifiers)
Start:
|
110,465,521 bp from pter |
End:
|
110,511,491 bp from pter |
Size:
|
45,971 bases |
Orientation:
|
minus strand |
|
Proteins
for C12orf76 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CL076_HUMAN, Q8N812 (See
protein sequence)Recommended Name: Uncharacterized protein C12orf76 Size: 135 amino acids; 14959 DaExplore the universe of human proteins at neXtProt for C12orf76: NX_Q8N812
C12orf76 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_997318.1
ENSEMBL proteins: ENSP00000447351 ENSP00000308368 ENSP00000450232 ENSP00000446788 ENSP00000447574 ENSP00000448915 ENSP00000449939
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
-- | -- |
C12orf76 for ontologies About GeneDecksing
C12orf76 Antibody Products:
Assay Products for C12orf76: |
Protein
Domains /
Families
for C12orf76 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8N812 1 Blocks protein family: IPB001400 Somatotropin hormone
|
Function
for C12orf76 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C12orf76 (NM_207435) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C12orf76 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C12orf76 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C12orf76 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
C12orf76 for ontologies About GeneDecksing
|
Pathways & Interactions
for C12orf76 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C12orf76
|
Drugs & Compounds
for C12orf76 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C12orf76
Search CenterWatch for drugs/clinical trials and news about C12orf76 / CL076
|
Transcripts
for C12orf76 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C12orf76 gene: NM_207435.1 Unigene Cluster for C12orf76: Chromosome 12 open reading frame 76 Hs.44817 [show with all ESTs]Unigene Representative Sequence: NM_2074359 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000546651 ENST00000309050(uc001tqb.1 uc001tqc.1 uc001tqd.1 uc001tqe.1 uc010sxx.1)
ENST00000549724 ENST00000548936 ENST00000551185 ENST00000546627 ENST00000547573
ENST00000548191(uc001tqf.1) ENST00000377158
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C12orf76 (NM_207435) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C12orf76 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C12orf76 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C12orf76
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C12orf76 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C12orf76 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C12orf76 |
Additional cDNA sequence: AF086409.1 AK021447.1 AK097461.1 BC041968.1 BC046185.1 BC133010.1 BC133012.1 BC144372.1 6 DOTS entries: DT.95365285 DT.121186476 DT.100033756 DT.415806 DT.97840144 DT.302915 24/185 AceView cDNA sequences (see all 185): BU187145 F10232 AI192042 R94171 AW163653 BM826623 AW189235 AI671526 AI223097 AI553906 AF086409 BG150241 BC046185 AI916291 BM423583 AI937472 BG700102 BE856049 AW044205 BQ221873 NM_207435 AW237534 AI739195 AA760686
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for C12orf76 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for C12orf76
|
Expression
for C12orf76 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C12orf76 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See C12orf76 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C12orf76
SOURCE GeneReport for Unigene cluster: Hs.44817
SABiosciences Custom PCR Arrays for C12orf76
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C12orf76
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C12orf76 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C12orf76 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C12orf76 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C12orf76 |
Orthologs
for C12orf76 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for C12orf76 (if available)
TreeFam Gene Tree for C12orf76 (if available) |
Paralogs
for C12orf76 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C12orf76 gene
18/81 SIMAP similar genes for C12orf76 using alignment to 6 protein entries: CL076_HUMAN (see all proteins)
(see all similar genes):ARL6IP5 CCNJL KIAA0101 NDC80 PPIL6 SMYD4
UTY LSM12 BIRC3 EEF1E1 EIF3K HINFP
MRPL45 RPS13 COQ5 SEC14L3 ZMAT1 C11orf80
C12orf76 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for C12orf76
PGOHUM00000261130 PGOHUM00000239948 PGOHUM00000261438
|
Genomic Variants
for C12orf76 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C12orf76 (110465521 - 110511491 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C12orf76: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C12orf76 |
|
Disorders
/ Diseases
for C12orf76 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C12orf76 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C12orf76 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C12orf76) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for C12orf76 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C12orf76 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C12orf76 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C12orf76 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C12orf76 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C12orf76 gene:
Search GeneIP for patents involving C12orf76
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C12orf76 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C12orf76 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C12orf76 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C12orf76 | | | OriGene Protein Over-expression Lysate for C12orf76 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C12orf76 | | OriGene 3'-UTR Clone for C12orf76 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C12orf76 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C12orf76 | | OriGene Custom Protein Services for C12orf76 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C12orf76 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C12orf76 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C12orf76 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C12orf76 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C12orf76 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C12orf76 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | C12orf76 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C12orf76 |
|  |  |  | | | | Search ThermoFisher Antibodies for C12orf76 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C12orf76 |
|
|
|
|
