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Aliases for C12orf75 Gene

Aliases for C12orf75 Gene

  • Chromosome 12 Open Reading Frame 75 2 3
  • Adipogenesis Down-Regulated 3 2 3
  • OCC-1 3 4
  • OCC1 3 4
  • AGD3 3 4
  • Putative Overexpressed In Colon Carcinoma-1 Protein Variant C 3
  • Overexpressed In Colon Carcinoma 1 Protein 3
  • Overexpressed In Colon Carcinoma 1 2
  • Overexpressed In Colon Carcinoma-1 3

External Ids for C12orf75 Gene

Previous GeneCards Identifiers for C12orf75 Gene

  • GC12P104154
  • GC12P105724
  • GC12P102783
  • GC12P105629

Summaries for C12orf75 Gene

GeneCards Summary for C12orf75 Gene

C12orf75 (Chromosome 12 Open Reading Frame 75) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf75 Gene

Genomics for C12orf75 Gene

Regulatory Elements for C12orf75 Gene

Genomic Location for C12orf75 Gene

Start:
105,235,290 bp from pter
End:
105,396,097 bp from pter
Size:
160,808 bases
Orientation:
Plus strand

Genomic View for C12orf75 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C12orf75 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf75 Gene

Proteins for C12orf75 Gene

  • Protein details for C12orf75 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAD7-OCC1_HUMAN
    Recommended name:
    Overexpressed in colon carcinoma 1 protein
    Protein Accession:
    Q8TAD7
    Secondary Accessions:

    Protein attributes for C12orf75 Gene

    Size:
    63 amino acids
    Molecular mass:
    6407 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH13920.2; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=AAH45812.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=AAH61920.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=AAH67897.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAC85391.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAC85392.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

neXtProt entry for C12orf75 Gene

Proteomics data for C12orf75 Gene at MOPED

Post-translational modifications for C12orf75 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf75 Gene

No data available for DME Specific Peptides for C12orf75 Gene

Domains for C12orf75 Gene

Protein Domains for C12orf75 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8TAD7

UniProtKB/Swiss-Prot:

OCC1_HUMAN :
  • Q8TAD7
Family:
  • Belongs to the OCC1 family.
genes like me logo Genes that share domains with C12orf75: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C12orf75 Gene

Function for C12orf75 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C12orf75 Gene

Localization for C12orf75 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C12orf75 Gene

Pathways for C12orf75 Gene

SuperPathways for C12orf75 Gene

No Data Available

Interacting Proteins for C12orf75 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000448536%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000448536 for C12orf75 Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for C12orf75 Gene

None

No data available for Pathways by source for C12orf75 Gene

Transcripts for C12orf75 Gene

Unigene Clusters for C12orf75 Gene

Chromosome 12 open reading frame 75:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C12orf75

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for C12orf75
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf75 Gene

No ASD Table

Relevant External Links for C12orf75 Gene

GeneLoc Exon Structure for
C12orf75
ECgene alternative splicing isoforms for
C12orf75

Expression for C12orf75 Gene

mRNA expression in normal human tissues for C12orf75 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C12orf75 Gene

This gene is overexpressed in Artery - Tibial (6.3) and Artery - Aorta (4.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C12orf75 Gene

SOURCE GeneReport for Unigene cluster for C12orf75 Gene Hs.368938

mRNA Expression by UniProt/SwissProt for C12orf75 Gene

Q8TAD7-OCC1_HUMAN
Tissue specificity: High expression in placenta, skeletal muscle, kidney and pancreas tissues. Absent or very faint expression in heart, brain, lung and liver. Expressed during adipogenic differentiation of mesenchymal stem cells (at protein level).
genes like me logo Genes that share expressions with C12orf75: view

In Situ Assay Products

Orthologs for C12orf75 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C12orf75 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf75 35
  • 98.94 (n)
  • 96.83 (a)
C12orf75 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C12orf75 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1500009L16Rik 16
1500009L16Rik 36
  • 86 (a)
OneToOne
chicken
(Gallus gallus)
Aves OCC-1 36
  • 66 (a)
OneToOne
Species with no ortholog for C12orf75:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf75 Gene

ENSEMBL:
Gene Tree for C12orf75 (if available)
TreeFam:
Gene Tree for C12orf75 (if available)

Paralogs for C12orf75 Gene

Selected SIMAP similar genes for C12orf75 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with C12orf75: view

No data available for Paralogs for C12orf75 Gene

Variants for C12orf75 Gene

Sequence variations from dbSNP and Humsavar for C12orf75 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs6797 -- 105,371,206(+) AACAA(G/T)GTGTA utr-variant-3-prime
rs715167 -- 105,333,848(-) TGCAT(C/G)AAAAA intron-variant
rs934414 -- 105,333,552(-) CTTTC(C/T)ACAAT intron-variant
rs1061749 -- 105,371,319(+) CTTCA(C/T)AGCTG utr-variant-3-prime
rs1344778 -- 105,343,502(+) GATCA(A/G)AGCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C12orf75 Gene

Variant ID Type Subtype PubMed ID
nsv510589 CNV Loss 20534489
nsv899500 CNV Gain 21882294
esv2746323 CNV Deletion 23290073
nsv510316 CNV Loss 20534489

Relevant External Links for C12orf75 Gene

HapMap Linkage Disequilibrium report
C12orf75

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf75 Gene

Disorders for C12orf75 Gene

Relevant External Links for C12orf75

Genetic Association Database (GAD)
C12orf75
genes like me logo Genes that share disorders with C12orf75: view

No data available for UniProtKB/Swiss-Prot for C12orf75 Gene

Publications for C12orf75 Gene

  1. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. (PMID: 19531736) Kikuchi K. … Aizawa Y. (Nucleic Acids Res. 2009) 2 3 4
  2. Cloning of the mRNA of overexpression in colon carcinoma-1: a sequence overexpressed in a subset of colon carcinomas. (PMID: 11890990) Pibouin L. … Goubin G. (Cancer Genet. Cytogenet. 2002) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C12orf75 Gene

Sources for C12orf75 Gene

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