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Aliases for C12orf71 Gene

Aliases for C12orf71 Gene

  • Chromosome 12 Open Reading Frame 71 2 3 5
  • Uncharacterized Protein C12orf71 3
  • HCG1794298 3

External Ids for C12orf71 Gene

Previous GeneCards Identifiers for C12orf71 Gene

  • GC12M027128
  • GC12M027233

Summaries for C12orf71 Gene

GeneCards Summary for C12orf71 Gene

C12orf71 (Chromosome 12 Open Reading Frame 71) is a Protein Coding gene.

Additional gene information for C12orf71 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf71 Gene

Genomics for C12orf71 Gene

Regulatory Elements for C12orf71 Gene

Enhancers for C12orf71 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H027547 1.9 FANTOM5 Ensembl ENCODE dbSUPER 14.2 -469.0 -468959 11 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 FOS SP5 PPFIBP1 C12orf71 SMCO2 ENSG00000248100 LOC100506578
GH12H026268 2.1 FANTOM5 Ensembl ENCODE dbSUPER 11.8 +811.6 811556 8 MLX FEZF1 SLC30A9 ZNF143 SP3 ZNF610 GLIS1 RCOR2 NBN NR2C1 BHLHE41 ENSG00000255858 ENSG00000257009 LOC100421617 ENSG00000256226 RASSF8-AS1 C12orf71 RASSF8 ENSG00000255968 ENSG00000255750
GH12H027523 1.7 FANTOM5 ENCODE dbSUPER 12.9 -440.5 -440465 3 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 FOS SP3 CEBPZ LOC729222 C12orf71 PPFIBP1 ENSG00000248100
GH12H027709 1.2 ENCODE 14.2 -626.9 -626896 2 HDGF FOXA2 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ENSG00000256377 MANSC4 ENSG00000256504 ENSG00000256226 C12orf71 KLHL42 MED21 HMGB1P49 MRPS35 ENSG00000252585
GH12H027176 1.9 FANTOM5 Ensembl ENCODE dbSUPER 8.2 -95.0 -94951 5 HDGF ATF1 SIN3A FEZF1 ELK1 FOS ATF7 RUNX3 JUNB TSHZ1 STK38L MED21 ENSG00000247903 C12orf71 PIR36462 ENSG00000256226
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C12orf71 on UCSC Golden Path with GeneCards custom track

Genomic Location for C12orf71 Gene

Chromosome:
12
Start:
27,081,057 bp from pter
End:
27,084,144 bp from pter
Size:
3,088 bases
Orientation:
Minus strand

Genomic View for C12orf71 Gene

Genes around C12orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C12orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C12orf71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf71 Gene

Proteins for C12orf71 Gene

  • Protein details for C12orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MTZ7-CL071_HUMAN
    Recommended name:
    Uncharacterized protein C12orf71
    Protein Accession:
    A8MTZ7

    Protein attributes for C12orf71 Gene

    Size:
    269 amino acids
    Molecular mass:
    30355 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C12orf71 Gene

Post-translational modifications for C12orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf71 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C12orf71 Gene

Domains & Families for C12orf71 Gene

Gene Families for C12orf71 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C12orf71 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C12orf71: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C12orf71 Gene

Function for C12orf71 Gene

Phenotypes From GWAS Catalog for C12orf71 Gene

Phenotypes for C12orf71 Gene

GenomeRNAi human phenotypes for C12orf71:
genes like me logo Genes that share phenotypes with C12orf71: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C12orf71
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf71 Gene

Localization for C12orf71 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C12orf71 gene
Compartment Confidence
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C12orf71 Gene

Pathways & Interactions for C12orf71 Gene

SuperPathways for C12orf71 Gene

No Data Available

Interacting Proteins for C12orf71 Gene

Gene Ontology (GO) - Biological Process for C12orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C12orf71 Gene

Drugs & Compounds for C12orf71 Gene

No Compound Related Data Available

Transcripts for C12orf71 Gene

mRNA/cDNA for C12orf71 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C12orf71 Gene

Chromosome 12 open reading frame 71:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C12orf71
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf71 Gene

No ASD Table

Relevant External Links for C12orf71 Gene

GeneLoc Exon Structure for
C12orf71
ECgene alternative splicing isoforms for
C12orf71

Expression for C12orf71 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C12orf71 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C12orf71 Gene

This gene is overexpressed in Testis (x12.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C12orf71 Gene



Protein tissue co-expression partners for C12orf71 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C12orf71 Gene:

C12orf71

SOURCE GeneReport for Unigene cluster for C12orf71 Gene:

Hs.334003
genes like me logo Genes that share expression patterns with C12orf71: view

Primer Products

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C12orf71 Gene

Orthologs for C12orf71 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C12orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf71 33
  • 98.76 (n)
C12orf71 34
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100684484 33
  • 74.63 (n)
C12orf71 34
  • 49 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C5H12orf71 33
  • 73.16 (n)
C12orf71 34
  • 46 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700034J05Rik 33 16 34
  • 64.3 (n)
rat
(Rattus norvegicus)
Mammalia LOC690784 33
  • 64.29 (n)
oppossum
(Monodelphis domestica)
Mammalia C12orf71 34
  • 25 (a)
OneToOne
Species where no ortholog for C12orf71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf71 Gene

ENSEMBL:
Gene Tree for C12orf71 (if available)
TreeFam:
Gene Tree for C12orf71 (if available)

Paralogs for C12orf71 Gene

Pseudogenes.org Pseudogenes for C12orf71 Gene

genes like me logo Genes that share paralogs with C12orf71: view

No data available for Paralogs for C12orf71 Gene

Variants for C12orf71 Gene

Sequence variations from dbSNP and Humsavar for C12orf71 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000129871 -- 27,085,369(+) TGTCA(C/T)TTTTC upstream-variant-2KB
rs1001286584 -- 27,084,413(+) TACAC(A/G)CACAG upstream-variant-2KB, utr-variant-5-prime
rs1001359626 -- 27,084,183(+) AGGAA(C/T)GTGGA upstream-variant-2KB, utr-variant-5-prime
rs1002287297 -- 27,083,336(+) CTAAG(A/C)ATCTC intron-variant, upstream-variant-2KB
rs1002359224 -- 27,083,117(+) TTGTA(A/T)TTTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C12orf71 Gene

Variant ID Type Subtype PubMed ID
dgv2417n54 CNV gain 21841781
esv2745664 CNV deletion 23290073
nsv557805 CNV loss 21841781
nsv832356 CNV gain 17160897

Variation tolerance for C12orf71 Gene

Residual Variation Intolerance Score: 73.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.54; 72.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C12orf71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C12orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf71 Gene

Disorders for C12orf71 Gene

Relevant External Links for C12orf71

Genetic Association Database (GAD)
C12orf71
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C12orf71

No disorders were found for C12orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf71 Gene

Publications for C12orf71 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4 60
  2. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 60

Products for C12orf71 Gene

Sources for C12orf71 Gene

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