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Aliases for C12orf71 Gene

Aliases for C12orf71 Gene

  • Chromosome 12 Open Reading Frame 71 2 3 5
  • HCG1794298 3

External Ids for C12orf71 Gene

Previous GeneCards Identifiers for C12orf71 Gene

  • GC12M027128
  • GC12M027233

Summaries for C12orf71 Gene

GeneCards Summary for C12orf71 Gene

C12orf71 (Chromosome 12 Open Reading Frame 71) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf71 Gene

Genomics for C12orf71 Gene

Regulatory Elements for C12orf71 Gene

Genomic Location for C12orf71 Gene

Chromosome:
12
Start:
27,081,057 bp from pter
End:
27,084,144 bp from pter
Size:
3,088 bases
Orientation:
Minus strand

Genomic View for C12orf71 Gene

Genes around C12orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C12orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C12orf71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf71 Gene

Proteins for C12orf71 Gene

  • Protein details for C12orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MTZ7-CL071_HUMAN
    Recommended name:
    Uncharacterized protein C12orf71
    Protein Accession:
    A8MTZ7

    Protein attributes for C12orf71 Gene

    Size:
    269 amino acids
    Molecular mass:
    30355 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C12orf71 Gene

Proteomics data for C12orf71 Gene at MOPED

Post-translational modifications for C12orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf71 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C12orf71 Gene

Domains & Families for C12orf71 Gene

Protein Domains for C12orf71 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C12orf71: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C12orf71 Gene

Function for C12orf71 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C12orf71 Gene

Localization for C12orf71 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C12orf71 Gene COMPARTMENTS Subcellular localization image for C12orf71 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C12orf71 Gene

Pathways & Interactions for C12orf71 Gene

SuperPathways for C12orf71 Gene

No Data Available

Interacting Proteins for C12orf71 Gene

Gene Ontology (GO) - Biological Process for C12orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C12orf71 Gene

Drugs & Compounds for C12orf71 Gene

No Compound Related Data Available

Transcripts for C12orf71 Gene

mRNA/cDNA for C12orf71 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C12orf71 Gene

Chromosome 12 open reading frame 71:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf71 Gene

No ASD Table

Relevant External Links for C12orf71 Gene

GeneLoc Exon Structure for
C12orf71
ECgene alternative splicing isoforms for
C12orf71

Expression for C12orf71 Gene

mRNA expression in normal human tissues for C12orf71 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C12orf71 Gene

This gene is overexpressed in Testis (x12.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C12orf71 Gene



SOURCE GeneReport for Unigene cluster for C12orf71 Gene Hs.334003

genes like me logo Genes that share expression patterns with C12orf71: view

Protein tissue co-expression partners for C12orf71 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C12orf71 Gene

Orthologs for C12orf71 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C12orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf71 35
  • 98.76 (n)
  • 99.26 (a)
C12orf71 36
  • 89 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C12orf71 36
  • 46 (a)
OneToOne
C5H12orf71 35
  • 73.16 (n)
  • 59.93 (a)
dog
(Canis familiaris)
Mammalia LOC100684484 35
  • 74.63 (n)
  • 58.96 (a)
C12orf71 36
  • 49 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700034J05Rik 16
1700034J05Rik 36
  • 38 (a)
OneToOne
1700034J05Rik 35
  • 64.3 (n)
  • 45.67 (a)
oppossum
(Monodelphis domestica)
Mammalia C12orf71 36
  • 25 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC690784 35
  • 64.29 (n)
  • 50 (a)
Species with no ortholog for C12orf71:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf71 Gene

ENSEMBL:
Gene Tree for C12orf71 (if available)
TreeFam:
Gene Tree for C12orf71 (if available)

Paralogs for C12orf71 Gene

Pseudogenes.org Pseudogenes for C12orf71 Gene

genes like me logo Genes that share paralogs with C12orf71: view

No data available for Paralogs for C12orf71 Gene

Variants for C12orf71 Gene

Sequence variations from dbSNP and Humsavar for C12orf71 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs708167 - 27,082,066(+) AAATA(C/T)CTGAA reference, missense
rs708168 -- 27,082,448(+) CTGTC(A/G)TCCTC reference, synonymous-codon
rs708169 -- 27,084,028(+) CACGT(A/G)GAAGA upstream-variant-2KB, utr-variant-5-prime
rs708170 -- 27,084,152(+) CCATG(A/G)CAACA upstream-variant-2KB
rs7294567 -- 27,083,660(+) CATAT(A/G)TATGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C12orf71 Gene

Variant ID Type Subtype PubMed ID
esv2745664 CNV Deletion 23290073
nsv898939 CNV Gain 21882294
nsv832356 CNV Gain 17160897

Variation tolerance for C12orf71 Gene

Residual Variation Intolerance Score: 73.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.54; 72.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C12orf71 Gene

HapMap Linkage Disequilibrium report
C12orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf71 Gene

Disorders for C12orf71 Gene

Relevant External Links for C12orf71

Genetic Association Database (GAD)
C12orf71
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C12orf71

No disorders were found for C12orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C12orf71 Gene

Publications for C12orf71 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4 67
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for C12orf71 Gene

Sources for C12orf71 Gene

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