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C12orf65 Gene

protein-coding   GIFtS: 46
GCID: GC12P123717

Chromosome 12 Open Reading Frame 65

  See C12orf65-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chromosome 12 Open Reading Frame 651 2
COXPD72 5
SPG552 5
Probable Peptide Chain Release Factor C12orf65, Mitochondrial2

External Ids:    HGNC: 267841   Entrez Gene: 915742   Ensembl: ENSG000001309217   OMIM: 6135415   UniProtKB: Q9H3J63   

Export aliases for C12orf65 gene to outside databases

Previous GC identifers: GC12P122283 GC12P120678


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for C12orf65 Gene:
This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination
in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop
codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and
encepthalomyopathy. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Aug 2010)

GeneCards Summary for C12orf65 Gene:
C12orf65 (chromosome 12 open reading frame 65) is a protein-coding gene. Diseases associated with C12orf65 include spastic paraplegia 55, autosomal recessive, and combined oxidative phosphorylation deficiency 7. GO annotations related to this gene include translation release factor activity.

UniProtKB/Swiss-Prot: CL065_HUMAN, Q9H3J6
Function: May act as a codon-independent translation release factor that has lost all stop codon specificity and
directs the termination of translation in mitochondrion (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the C12orf65 gene promoter:
         FOXI1   HFH-3   GATA-3   FOXD3   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): C12orf65 promoter sequence
   Search Chromatin IP Primers for C12orf65

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat C12orf65


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

C12orf65 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C12orf65 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P123717:  view genomic region     (about GC identifiers)

Start:
123,717,463 bp from pter      End:
123,742,506 bp from pter
Size:
25,044 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CL065_HUMAN, Q9H3J6 (See protein sequence)
Recommended Name: Probable peptide chain release factor C12orf65, mitochondrial precursor  
Size: 166 amino acids; 18828 Da
Caution: In contrast to other members of the family, lacks the regions that come into close contact with the mRNA
in the ribosomal A-site and determine the STOP codon specificity, suggesting a loss of codon specificity for
translation release factor activity
Secondary accessions: Q8WUC6
Alternative splicing: 2 isoforms:  Q9H3J6-1   Q9H3J6-2   

Explore the universe of human proteins at neXtProt for C12orf65: NX_Q9H3J6

Explore proteomics data for C12orf65 at MOPED


See C12orf65 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001137377.1  NP_001181924.1  NP_689482.1  

ENSEMBL proteins: 
 ENSP00000253233   ENSP00000443072   ENSP00000441796   ENSP00000444843   ENSP00000391513  
 ENSP00000390647  

C12orf65 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for C12orf65

 
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Search eBioscience for ELISAs for C12orf65 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR014720 dsRNA-bd_dom
 IPR000352 Pep_chain_release_fac_I_II

Graphical View of Domain Structure for InterPro Entry Q9H3J6

ProtoNet protein and cluster: Q9H3J6

UniProtKB/Swiss-Prot: CL065_HUMAN, Q9H3J6
Similarity: Belongs to the prokaryotic/mitochondrial release factor family


Find genes that share domains with C12orf65           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CL065_HUMAN, Q9H3J6
Function: May act as a codon-independent translation release factor that has lost all stop codon specificity and
directs the termination of translation in mitochondrion (By similarity)

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003747translation release factor activity IEA--
     
Find genes that share ontologies with C12orf65           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for C12orf65
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   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for C12orf65

miRNA
Products:
    
miRTarBase miRNAs that target C12orf65:
hsa-mir-215-5p (MIRT024748), hsa-mir-222-3p (MIRT046767), hsa-mir-192-5p (MIRT026416), hsa-mir-331-3p (MIRT043547), hsa-mir-130b-3p (MIRT020179)

Block miRNA regulation of human, mouse, rat C12orf65 using miScript Target Protectors
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SwitchGear 3'UTR luciferase reporter plasmidC12orf65 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat C12orf65

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GenScript: all cDNA clones in your preferred vector (see all 3): C12orf65 (NM_152269)
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C12orf65


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CL065_HUMAN, Q9H3J6: Mitochondrion
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion5
cytosol2
nucleus2

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion NAS--

Find genes that share ontologies with C12orf65           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for C12orf65
Interactions:

    Search GeneGlobe Interaction Network for C12orf65

STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

Selected Interacting proteins for C12orf65 (Q9H3J63 ENSP000002532334) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
InteractantInteraction Details
GeneCardExternal ID(s)
NFYCQ139523I2D: score=2 
RPS13ENSP000002281404STRING: ENSP00000228140
RPS20ENSP000000095894STRING: ENSP00000009589
RPS3ENSP000002785724STRING: ENSP00000278572
RPS11ENSP000002706254STRING: ENSP00000270625
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006415translational termination ----
GO:0008219cell death IEA--

Find genes that share ontologies with C12orf65           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for C12orf65 (CL065)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for C12orf65 gene (3 alternative transcripts): 
NM_001143905.2  NM_001194995.1  NM_152269.4  

Unigene Cluster for C12orf65:

Chromosome 12 open reading frame 65
Hs.319128  [show with all ESTs]
Unigene Representative Sequence: AK095982
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000253233(uc001uen.3 uc001ueo.3) ENST00000538888 ENST00000425637
ENST00000536130 ENST00000546132 ENST00000543139 ENST00000429587 ENST00000366329(uc021rft.1 uc010tan.2)

miRNA
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SwitchGear 3'UTR luciferase reporter plasmidC12orf65 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for C12orf65
Predesigned siRNA for gene silencing in human, mouse, rat C12orf65
Clone
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OriGene ORF clones in mouse, rat for C12orf65
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GenScript: all cDNA clones in your preferred vector (see all 3): C12orf65 (NM_152269)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C12orf65
Primer
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  QuantiFast Probe-based Assays in human, mouse, rat C12orf65

Additional mRNA sequence: 

AF061733.1 AK025908.1 AK095982.1 BC018145.1 BC062329.1 

15 DOTS entries:

DT.409940  DT.95163677  DT.121109031  DT.121108966  DT.91723902  DT.100024585  DT.100813359  DT.91965695 
DT.100813360  DT.121108962  DT.91723890  DT.92452167  DT.95163678  DT.121108973  DT.91695275 

Selected AceView cDNA sequences (see all 151):

AI097203 AI686673 AI621052 CR612064 AI745266 AI262986 BQ188813 N89836 
AI697566 BF592978 AI278155 AI656830 AW613587 BM564488 BE220427 AW630171 
AI991987 AW007238 BP870576 AA868983 AA693948 BU155948 BF109377 AI939449 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for C12orf65    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b
SP1:                    -     -                 -               
SP2:                    -     -                                 
SP3:                          -                 -               
SP4:                    -     -     -     -     -               
SP5:                                                            


ECgene alternative splicing isoforms for C12orf65

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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C12orf65 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CTACTGCATA
C12orf65 Expression
About this image

C12orf65 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

C12orf65 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.319128
    Custom PCR Arrays for C12orf65
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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C12orf65

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for C12orf65 gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia 2810006K23Rik1 , 5 RIKEN cDNA 2810006K23 gene1, 5 78.47(n)1
78.47(a)1
  5 (63.52 cM)5
726501  NM_001134717.21  NP_001128189.11 
 1243280895 
chicken
(Gallus gallus)
Aves C15H12ORF651 chromosome 15 open reading frame, human C12orf65 61.74(n)
59.15(a)
  416827  NM_001252088.1  NP_001239017.1 
lizard
(Anolis carolinensis)
Reptilia C12orf656
chromosome 12 open reading frame 65
51(a)
1 ↔ 1
LGb(1872621-1877443)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1017344521 chromosome unknown open reading frame, human C12orf65 66.92(n)
64.62(a)
  101734452  XM_004910522.1  XP_004910579.1 
zebrafish
(Danio rerio)
Actinopterygii LOC1000044521 uncharacterized LOC100004452 65.69(n)
64.71(a)
  100004452  XM_001340005.4  XP_001340041.2 
fruit fly
(Drosophila melanogaster)
Insecta CG301006
--
40(a)
1 ↔ 1
2R(12178958-12179774)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes (YLR281C)4 Putative protein of unknown function; green fluorescent more   --   12(704960-704493) 850987  NP_013383.1 


ENSEMBL Gene Tree for C12orf65 (if available)
TreeFam Gene Tree for C12orf65 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for C12orf65 (see all 565)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 12 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1462392221,2
C--120678559(+) AGGGA-/GCCGCGC 3 -- us2k10--------
rs347867651,2
C--120683317(+) TTTTTT/-GAGAC 3 -- int11Minor allele frequency- -:0.00CSA 2
rs803476901,2
C--120684826(+) TGTTTTTTT/-  
        
GTTTT
3 -- int11Minor allele frequency- -:0.00CSA 2
rs1120601981,2
C--120686566(+) TTTTGT/-TTTTG 3 -- int11Minor allele frequency- -:0.50CSA 2
rs3677985381,2
C--120686566(+) TTTGT-/TTTG  
        
TTTTG
3 -- int10--------
rs787889841,2
C--120691926(+) AGTGC-/AAATGG 3 -- int11Minor allele frequency- A:0.00CSA 2
rs1508293831,2
C--120694377(+) ACACA-/AGGCACT 3 -- int10--------
rs58015101,2
C,F--120697837(+) GTCTCA/-AAAAA 3 -- int1 trp32Minor allele frequency- -:0.50NA CSA 4
rs108464881,2
C,A,H--120698839(+) TTTTTG/TGAGAC 3 -- int1 trp32Minor allele frequency- T:0.00NA 4
rs128189861,2
A--120698842(+) tttgaA/Gacact 3 -- int10--------

HapMap Linkage Disequilibrium report for C12orf65 (123717463 - 123742506 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for C12orf65:    About this table    
Variant IDTypeSubtypePubMed ID
esv28503CNV Loss19812545
esv996114CNV Gain20482838

Human Gene Mutation Database (HGMD): C12orf65
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing C12orf65
DNA2.0 Custom Variant and Variant Library Synthesis for C12orf65

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613541   
OMIM disorders: 613559  615035  
UniProtKB/Swiss-Prot: CL065_HUMAN, Q9H3J6
  • Combined oxidative phosphorylation deficiency 7 (COXPD7) [MIM:613559]: A mitochondrial disease resulting
    in encephalomyopathy. Clinical manifestations include psychomotor delay and regression, ataxia, optic atrophy,
    nystagmus and muscle atrophy and weakness. Note=The disease is caused by mutations affecting the gene represented
    in this entry
  • Spastic paraplegia 55, autosomal recessive (SPG55) [MIM:615035]: A form of spastic paraplegia, a
    neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower
    limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include
    difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking.
    Complicated forms are characterized by the addition of such neurological features as spastic quadriparesis,
    seizures, dementia, amyotrophy, extrapyramidal disturbance, cerebral or cerebellar atrophy, optic atrophy, and
    peripheral neuropathy, as well as by extra neurological manifestations such as dysmorphism, albinism, retinitis
    pigmentosa, deafness, dementia, amyotrophy and ichthyosis. Note=The disease is caused by mutations affecting the
    gene represented in this entry

  • 2 diseases for C12orf65:    
    About MalaCards
    spastic paraplegia 55, autosomal recessive    combined oxidative phosphorylation deficiency 7

    1 disease from the University of Copenhagen DISEASES database for C12orf65:
    Optic atrophy

    Find genes that share disorders with C12orf65           About GenesLikeMe


    Export disorders for C12orf65 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for C12orf65 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with C12orf65)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A homozygous mutation of C12orf65 causes spastic paraplegia with optic atrophy and neuropathy (SPG55). (PubMed id 23188110)1, 2, 3 Shimazaki H....Nakano I. (J. Med. Genet. 2012)
    2. Mutations in C12orf65 in patients with encephalomyopathy and a mitochondrial translation defect. (PubMed id 20598281)1, 2, 3 Antonicka H.... Shoubridge E.A. (Am. J. Hum. Genet. 2010)
    3. Evolution and diversification of the organellar release factor family. (PubMed id 22688947)1, 3 Duarte I....Huynen M. (Mol. Biol. Evol. 2012)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Novel C12orf65 mutations in patients with axonal neuropathy and optic atrophy. (PubMed id 24198383)1 Tucci A....Houlden H. (J. Neurol. Neurosurg. Psychiatr. 2013)
    6. Mutations in the mitochondrial gene C12ORF65 lead to syndromic autosomal recessive intellectual disability and show genotype phenotype correlation. (PubMed id 24080142)1 Buchert R....Abou Jamra R. (Eur J Med Genet 2013)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    9. Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65. (PubMed id 22821833)1 Kogure H....Nameki N. (Proteins 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 91574 HGNC: 26784 AceView: FLJ38663 Ensembl:ENSG00000130921 euGenes: HUgn91574
    ECgene: C12orf65 H-InvDB: C12orf65

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for C12orf65 Pharmacogenomics, SNPs, Pathways

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    Patent Information for C12orf65 gene:
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