Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C12orf50 Gene

Aliases for C12orf50 Gene

  • Chromosome 12 Open Reading Frame 50 2 3

External Ids for C12orf50 Gene

Summaries for C12orf50 Gene

GeneCards Summary for C12orf50 Gene

C12orf50 (Chromosome 12 Open Reading Frame 50) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf50 Gene

Genomics for C12orf50 Gene

Genomic Location for C12orf50 Gene

Start:
87,980,035 bp from pter
End:
88,034,037 bp from pter
Size:
54,003 bases
Orientation:
Minus strand

Genomic View for C12orf50 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C12orf50 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf50 Gene

Regulatory Elements for C12orf50 Gene

Proteins for C12orf50 Gene

  • Protein details for C12orf50 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA57-CL050_HUMAN
    Recommended name:
    Uncharacterized protein C12orf50
    Protein Accession:
    Q8NA57
    Secondary Accessions:
    • Q6P674

    Protein attributes for C12orf50 Gene

    Size:
    414 amino acids
    Molecular mass:
    47326 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C12orf50 Gene

Proteomics data for C12orf50 Gene at MOPED

Post-translational modifications for C12orf50 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf50 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C12orf50 Gene

Domains for C12orf50 Gene

Protein Domains for C12orf50 Gene

ProtoNet:
genes like me logo Genes that share domains with C12orf50: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C12orf50 Gene

Function for C12orf50 Gene

Gene Ontology (GO) - Molecular Function for C12orf50 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C12orf50: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C12orf50 Gene

Localization for C12orf50 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C12orf50 Gene COMPARTMENTS Subcellular localization image for C12orf50 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for C12orf50 Gene

Pathways for C12orf50 Gene

SuperPathways for C12orf50 Gene

No Data Available

Interacting Proteins for C12orf50 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000298699%0d%0a9606.ENSP00000416097%0d%0a
Selected Interacting proteins: ENSP00000298699 Q8NA57-CL050_HUMAN for C12orf50 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for C12orf50 Gene

None

No data available for Pathways by source for C12orf50 Gene

Transcripts for C12orf50 Gene

Unigene Clusters for C12orf50 Gene

Chromosome 12 open reading frame 50:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf50 Gene

No ASD Table

Relevant External Links for C12orf50 Gene

GeneLoc Exon Structure for
C12orf50
ECgene alternative splicing isoforms for
C12orf50

Expression for C12orf50 Gene

mRNA expression in normal human tissues for C12orf50 Gene

mRNA differential expression in normal tissues according to GTEx for C12orf50 Gene

This gene is overexpressed in Testis (51.4).

SOURCE GeneReport for Unigene cluster for C12orf50 Gene Hs.112930

genes like me logo Genes that share expressions with C12orf50: view

Orthologs for C12orf50 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C12orf50 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf50 36
  • 99.28 (n)
  • 98.79 (a)
C12orf50 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C12orf50 37
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C12orf50 37
  • 87 (a)
OneToOne
C15H12orf50 36
  • 92.11 (n)
  • 87.92 (a)
mouse
(Mus musculus)
Mammalia 1700017N19Rik 36
  • 85.88 (n)
  • 82.57 (a)
1700017N19Rik 16
1700017N19Rik 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C12orf50 37
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C12orf50 37
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC500827 36
  • 86.84 (n)
  • 83.29 (a)
chicken
(Gallus gallus)
Aves C12ORF50 36
  • 60.63 (n)
  • 47.08 (a)
C12orf50 37
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C12orf50 37
  • 42 (a)
OneToOne
Species with no ortholog for C12orf50:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C12orf50 Gene

ENSEMBL:
Gene Tree for C12orf50 (if available)
TreeFam:
Gene Tree for C12orf50 (if available)

Paralogs for C12orf50 Gene

Selected SIMAP similar genes for C12orf50 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with C12orf50: view

No data available for Paralogs for C12orf50 Gene

Variants for C12orf50 Gene

Sequence variations from dbSNP and Humsavar for C12orf50 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs2730488 -- 88,028,661(-) GTCAA(A/T)CTTAG intron-variant
rs2731639 -- 88,029,597(+) GTTCT(C/G)GTTGA upstream-variant-2KB
rs2731640 -- 88,030,279(+) tagaa(A/T)cccct upstream-variant-2KB
rs4275694 -- 88,016,760(+) TTGCT(A/C/G)TTATG intron-variant
rs4306350 -- 88,016,908(+) CATGC(C/T)TGGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C12orf50 Gene

Variant ID Type Subtype PubMed ID
esv2746169 CNV Deletion 23290073
esv2746170 CNV Deletion 23290073
esv2746171 CNV Deletion 23290073

Relevant External Links for C12orf50 Gene

HapMap Linkage Disequilibrium report
C12orf50

Disorders for C12orf50 Gene

Relevant External Links for C12orf50

Genetic Association Database (GAD)
C12orf50
Human Genome Epidemiology (HuGE) Navigator
C12orf50
genes like me logo Genes that share disorders with C12orf50: view

No data available for UniProtKB/Swiss-Prot for C12orf50 Gene

Publications for C12orf50 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. The global gene-expression profiles of U-937 human macrophages treated with Tat peptide and Tat-FITC conjugate. (PMID: 22632162) Lin C.W. … Jan M.S. (J Drug Target 2012) 3

Products for C12orf50 Gene

Sources for C12orf50 Gene

Back to Top

Content