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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C12orf5 Gene

protein-coding   GIFtS: 50
GCID: GC12P004430

Chromosome 12 Open Reading Frame 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chromosome 12 Open Reading Frame 51 2     Fructose-2,6-Bisphosphate 2-Phosphatase2
TP53-Induced Glycolysis And Apoptosis Regulator1 2 3     Probable Fructose-2,6-Bisphosphatase TIGAR2
TIGAR2 5     Transactivated By NS3TP2 Protein2
FR2BP2     EC 3.1.3.463
Fructose-2,6-Bisphosphatase TIGAR2     

External Ids:    HGNC: 11851   Entrez Gene: 571032   Ensembl: ENSG000000782377   OMIM: 6107755   UniProtKB: Q9NQ883   

Export aliases for C12orf5 gene to outside databases

Previous GC identifers: GC12P004167 GC12P004322 GC12P004300


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for C12orf5 Gene:
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity
to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein
functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this
protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA
damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
(provided by RefSeq, Jul 2008)

GeneCards Summary for C12orf5 Gene: 
C12orf5 (chromosome 12 open reading frame 5) is a protein-coding gene. Diseases associated with C12orf5 include rickets, and lymphoblastic leukemia. GO annotations related to this gene include fructose-2,6-bisphosphate 2-phosphatase activity.

UniProtKB/Swiss-Prot: TIGAR_HUMAN, Q9NQ88
Function: Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate.
Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive
oxygen species and against apoptosis induced by tp53

Gene Wiki entry for C12orf5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009759.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C12orf5 gene promoter:
         E2F-4   E2F-3a   E2F-5   p300   E2F-2   CBF-C   E2F   E2F-1   CP1A   CP1C   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C12orf5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C12orf5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.3   Ensembl cytogenetic band:  12p13.32   HGNC cytogenetic band: 12p13.32

C12orf5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C12orf5 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P004430:  view genomic region     (about GC identifiers)

Start:
4,430,359 bp from pter      End:
4,469,194 bp from pter
Size:
38,836 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TIGAR_HUMAN, Q9NQ88 (See protein sequence)
Recommended Name: Fructose-2,6-bisphosphatase TIGAR  
Size: 270 amino acids; 30063 Da
Subunit: Monomer (By similarity)
Caution: Not expected to have any kinase activity
1 PDB 3D structure from and Proteopedia for C12orf5:
3DCY (3D)    
Secondary accessions: B2R840

Explore the universe of human proteins at neXtProt for C12orf5: NX_Q9NQ88

Explore proteomics data for C12orf5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NQ88

  • C12orf5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    C12orf5 Protein Expression
    REFSEQ proteins: NP_065108.1  
    ENSEMBL proteins: 
     ENSP00000179259  

    Human Recombinant Protein Products for C12orf5: 
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    Novus Biologicals C12orf5 Proteins
    Novus Biologicals C12orf5 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--

    C12orf5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001345 PG/BPGM_mutase_AS
     IPR013078 His_Pase_superF_clade-1

    Graphical View of Domain Structure for InterPro Entry Q9NQ88

    ProtoNet protein and cluster: Q9NQ88

    1 Blocks protein domain: IPB001345 Phosphoglycerate/bisphosphoglycerate mutase

    UniProtKB/Swiss-Prot: TIGAR_HUMAN, Q9NQ88
    Similarity: Belongs to the phosphoglycerate mutase family


    C12orf5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TIGAR_HUMAN, Q9NQ88
    Function: Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate.
    Inhibits glycolysis by reducing cellular levels of fructose-2,6-bisphosphate. May protect cells against reactive
    oxygen species and against apoptosis induced by tp53
    Catalytic activity: Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
    Induction: Rapidly up-regulated by p53/TP53

         Enzyme Number (IUBMB): EC 3.1.3.461

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004331fructose-2,6-bisphosphate 2-phosphatase activity IEA--
         
    C12orf5 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for 9630033F20Rik):
     cardiovascular system  cellular  homeostasis/metabolism  muscle  no phenotypic analysis 

    C12orf5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out 9630033F20Riktm1.2Smat for C12orf5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for C12orf5 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for C12orf5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Fructose and mannose metabolism
    Fructose and mannose metabolism
    2Direct p53 effectors
    Direct p53 effectors

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for C12orf5
        Direct p53 effectors


    1         Kegg Pathway  (Kegg details for C12orf5):
        Fructose and mannose metabolism


    C12orf5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C12orf5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/14 Interacting proteins for C12orf5 (ENSP000001792594) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FBP1ENSP000003644754STRING: ENSP00000364475
    FBP2ENSP000003644864STRING: ENSP00000364486
    HK2ENSP000002905734STRING: ENSP00000290573
    HK3ENSP000002924324STRING: ENSP00000292432
    HKDC1ENSP000003466434STRING: ENSP00000346643
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010666positive regulation of cardiac muscle cell apoptotic process IEA--
    GO:1901525negative regulation of macromitophagy IEA--
    GO:2000378negative regulation of reactive oxygen species metabolic process IEA--

    C12orf5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C12orf5 (TIGAR)

    Search CenterWatch for drugs/clinical trials and news about C12orf5 / TIGAR

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for C12orf5 gene: 
    NM_020375.2  

    Unigene Cluster for C12orf5:

    Chromosome 12 open reading frame 5
    Hs.504545  [show with all ESTs]
    Unigene Representative Sequence: NM_020375
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000179259(uc001qmp.3) ENST00000539671 ENST00000537251
    miRNA
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    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate C12orf5 (see all 14):
    hsa-miR-875-3p hsa-miR-188-5p hsa-miR-605 hsa-miR-410 hsa-miR-520a-5p hsa-miR-211 hsa-miR-144 hsa-miR-204
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C12orf5
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    Additional mRNA sequence: 

    AJ272206.1 AK313226.1 AY425618.1 BC012340.1 

    5 DOTS entries:

    DT.441019  DT.99960633  DT.100725881  DT.408307  DT.95161847 

    24/100 AceView cDNA sequences (see all 100):

    AI376293 F09684 AA503851 AI625405 AW236937 AW104400 BQ011607 BF061847 
    AA570142 AI341056 AI803333 AI741732 CA434904 AI949681 AI861829 AI889011 
    AA897774 AI928246 AI805174 CR613889 CK820201 AI435416 AA903744 AI968331 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C12orf5 expression in normal human tissues (normalized intensities)      C12orf5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTATATTGA
    C12orf5 Expression
    About this image


    C12orf5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 15 entries
             Thalamus
             Septum   
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             huvec   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Dorsal Horn   
     
     Umbilical Cord (Extraembryonic Tissues)
             huvec   
     
     Blood (Cardiovascular System)
             blood outgrowth endothelial cell   

    See C12orf5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C12orf5

    SOURCE GeneReport for Unigene cluster: Hs.504545
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for C12orf5 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 9630033F20Rik1 , 5 RIKEN cDNA 9630033F20 gene1, 5 75.56(n)1
    73.31(a)1
      6 (61.92 cM)5
    3198011  NM_177003.51  NP_795977.11 
     1270851165 
    chicken
    (Gallus gallus)
    Aves C1H12orf51 chromosome 1 open reading frame, human C12orf5 66.41(n)
    59.54(a)
      419040  XM_417232.3  XP_417232.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tigarb1 tp53-induced glycolysis and apoptosis regulator b 48.66(n)
    42.74(a)
      393160  NM_200191.1  NP_956485.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YOR283W6
    Phosphatase with a broad substrate specificity and...
    28(a)
    1 ↔ 1
    XV(847453-848145)


    ENSEMBL Gene Tree for C12orf5 (if available)
    TreeFam Gene Tree for C12orf5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/878 SNPs in C12orf5 are shown (see all 878)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs73131341,2
    C,F--4428410(+) gtgatA/Gttaca 1 -- us2k16Minor allele frequency- G:0.13NA CSA WA EA 363
    rs1449899681,2
    C--4428714(+) ATTTTC/TTTTTT 1 -- us2k10--------
    rs97399061,2
    C,F,A,H--4428721(+) ttttaA/Gttctc 1 -- us2k1 tfbs34Minor allele frequency- G:0.00NS EA 418
    rs1829709891,2
    --4428784(+) GTGAGC/TGCACA 1 -- us2k10--------
    rs1419456921,2
    --4428826(+) CCTGAC/TGCACG 1 -- us2k10--------
    rs97377061,2
    C,F,A--4428845(+) gctgcT/Agtgta 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1863074761,2
    --4428907(+) TGATGA/GGGGTG 1 -- us2k10--------
    rs1902793591,2
    --4428923(+) TTTGGC/TGGGAA 1 -- us2k10--------
    rs762143731,2
    F--4428968(+) GGTGGC/AGTAGG 1 -- us2k12Minor allele frequency- A:0.50NA CSA 4
    rs1825283651,2
    --4429228(+) GCAGGC/TGCCTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for C12orf5 (4430359 - 4469194 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for C12orf5:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv523578CNV Loss19592680
    nsv528492CNV Loss19592680
    nsv468985CNV Loss19166990
    nsv519278CNV Loss19592680
    nsv832317CNV Gain17160897
    esv275025CNV Gain+Loss21479260

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610775    OMIM disorders: --

    4 diseases for C12orf5:    About MalaCards
    rickets    lymphoblastic leukemia    leukemia    breast cancer


    C12orf5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): C12orf5

    Export disorders for C12orf5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C12orf5 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with C12orf5)
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    1. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. (PubMed id 16839880)1, 2, 3 Bensaad K.... Vousden K.H. (2006)
    2. Modulation of intracellular ROS levels by TIGAR contr ols autophagy. (PubMed id 19713938)1, 3 Bensaad K....Vousden K.H. (2009)
    3. Germline genomic variants associated with childhood a cute lymphoblastic leukemia. (PubMed id 19684603)1, 4 TreviA+o L.R....Relling M.V. (2009)
    4. Identification of TIGAR in the equilibrative nucleosi de transporter 2-mediated response to fludarabine in chronic lymphocytic leukem ia cells. (PubMed id 18945750)1, 3 LA^pez-Guerra M....Pastor-Anglada M. (2008)
    5. Identification of novel p53 target genes in ionizing radiation response. (PubMed id 16140933)1, 3 Jen K.Y. and Cheung V.G. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. (PubMed id 11062477)1, 2 White K.E.... Strom T.M. (2000)
    8. Common genetic variation and antidepressant efficacy i n major depressive disorder: a meta-analysis of three genome-wide pharmacogeneti c studies. (PubMed id 23377640)1 (2013)
    9. Genome-wide association analyses in East Asians identi fy new susceptibility loci for colorectal cancer. (PubMed id 23263487)1 Jia W.H....Zheng W. (2013)
    10. TIGAR is required for efficient intestinal regeneratio n and tumorigenesis. (PubMed id 23726973)1 Cheung E.C....Vousden K.H. (2013)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57103 HGNC: 1185 AceView: C12orf5 Ensembl:ENSG00000078237 euGenes: HUgn57103
    ECgene: C12orf5 Kegg: 57103 H-InvDB: C12orf5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C12orf5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for C12orf5 gene:
    Search GeneIP for patents involving C12orf5

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