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Aliases for C12orf10 Gene

Aliases for C12orf10 Gene

  • Chromosome 12 Open Reading Frame 10 2 3
  • Melanocyte Proliferating Gene 1 2 3
  • MYG1 3 6
  • UPF0160 Protein MYG1, Mitochondrial 3
  • Melanocyte Related Gene 2
  • Melanocyte Related 3
  • MSTP024 3
  • MST024 3
  • Gamm1 3
  • MYG 3

External Ids for C12orf10 Gene

Previous GeneCards Identifiers for C12orf10 Gene

  • GC12M054008
  • GC12M053803
  • GC12P053411
  • GC12P051979
  • GC12P053693
  • GC12P050734

Summaries for C12orf10 Gene

GeneCards Summary for C12orf10 Gene

C12orf10 (Chromosome 12 Open Reading Frame 10) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C12orf10 Gene

Genomics for C12orf10 Gene

Regulatory Elements for C12orf10 Gene

Transcription factor binding sites by QIAGEN in the C12orf10 gene promoter:

Genomic Location for C12orf10 Gene

Start:
53,299,686 bp from pter
End:
53,307,181 bp from pter
Size:
7,496 bases
Orientation:
Plus strand

Genomic View for C12orf10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C12orf10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C12orf10 Gene

Proteins for C12orf10 Gene

  • Protein details for C12orf10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HB07-MYG1_HUMAN
    Recommended name:
    UPF0160 protein MYG1, mitochondrial
    Protein Accession:
    Q9HB07
    Secondary Accessions:

    Protein attributes for C12orf10 Gene

    Size:
    376 amino acids
    Molecular mass:
    42449 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C12orf10 Gene

Proteomics data for C12orf10 Gene at MOPED

Post-translational modifications for C12orf10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C12orf10 Gene

No data available for DME Specific Peptides for C12orf10 Gene

Domains for C12orf10 Gene

Protein Domains for C12orf10 Gene

Suggested Antigen Peptide Sequences for C12orf10 Gene

Graphical View of Domain Structure for InterPro Entry

Q9HB07

UniProtKB/Swiss-Prot:

MYG1_HUMAN :
  • Q9HB07
Family:
  • Belongs to the UPF0160 (MYG1) family.
genes like me logo Genes that share domains with C12orf10: view

No data available for Gene Families for C12orf10 Gene

Function for C12orf10 Gene

Gene Ontology (GO) - Molecular Function for C12orf10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C12orf10: view

Phenotypes for C12orf10 Gene

MGI mutant phenotypes for C12orf10:
inferred from 1 alleles
GenomeRNAi human phenotypes for C12orf10:
genes like me logo Genes that share phenotypes with C12orf10: view

miRNA for C12orf10 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for C12orf10 Gene

Localization for C12orf10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C12orf10 Gene

Nucleus. Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C12orf10 Gene COMPARTMENTS Subcellular localization image for C12orf10 gene
Compartment Confidence
mitochondrion 5
nucleus 5
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C12orf10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 19014353
GO:0005654 nucleoplasm IDA --
GO:0005739 mitochondrion IDA 19014353
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with C12orf10: view

Pathways for C12orf10 Gene

SuperPathways for C12orf10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C12orf10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035641 locomotory exploration behavior IEA --
GO:0043473 pigmentation NAS 16996721
genes like me logo Genes that share ontologies with C12orf10: view

No data available for Pathways by source for C12orf10 Gene

Transcripts for C12orf10 Gene

Unigene Clusters for C12orf10 Gene

Chromosome 12 open reading frame 10:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C12orf10 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b
SP1: - - - - -
SP2: - - - - - -
SP3: - - - -
SP4: - - - -
SP5: -
SP6: -
SP7: - - - - - -
SP8:

Relevant External Links for C12orf10 Gene

GeneLoc Exon Structure for
C12orf10
ECgene alternative splicing isoforms for
C12orf10

Expression for C12orf10 Gene

mRNA expression in normal human tissues for C12orf10 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for C12orf10 Gene

SOURCE GeneReport for Unigene cluster for C12orf10 Gene Hs.655988

mRNA Expression by UniProt/SwissProt for C12orf10 Gene

Q9HB07-MYG1_HUMAN
Tissue specificity: Ubiquitously expressed, with highest levels in testis.
genes like me logo Genes that share expressions with C12orf10: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for C12orf10 Gene

Orthologs for C12orf10 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for C12orf10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf10 35
  • 99.38 (n)
  • 99.2 (a)
C12orf10 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C5H12orf10 35
  • 86.99 (n)
  • 88.62 (a)
C5H12orf10 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C12orf10 36
  • 85 (a)
OneToOne
C27H12orf10 35
  • 88.99 (n)
  • 91.3 (a)
mouse
(Mus musculus)
Mammalia Myg1 35
  • 85.51 (n)
  • 88.04 (a)
Myg1 16
Myg1 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Myg1 35
  • 86.94 (n)
  • 88.38 (a)
chicken
(Gallus gallus)
Aves C12ORF10 35
  • 66.89 (n)
  • 69.15 (a)
lizard
(Anolis carolinensis)
Reptilia C12orf10 36
  • 66 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.24401 35
tropical clawed frog
(Silurana tropicalis)
Amphibia c12orf10 35
  • 63.73 (n)
  • 67.35 (a)
Str.20255 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4414 35
zebrafish
(Danio rerio)
Actinopterygii C11H12orf10 36
  • 53 (a)
OneToOne
wufa14e09 35
zgc:136866 35
  • 60.62 (n)
  • 59.63 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002408 35
  • 53.59 (n)
  • 48.5 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11980 35
  • 51.78 (n)
  • 44.95 (a)
CG11980 36
  • 41 (a)
OneToOne
CG11980 37
  • 41 (a)
worm
(Caenorhabditis elegans)
Secernentea C27H6.8 35
  • 53.06 (n)
  • 49.05 (a)
C27H6.8 36
  • 45 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGR145C 35
  • 54.54 (n)
  • 46.75 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 43 (a)
OneToOne
-- 38
YER156C 35
  • 52.15 (n)
  • 45.71 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C11671g 35
  • 48.46 (n)
  • 46.91 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G41970 35
  • 54.71 (n)
  • 52.06 (a)
rice
(Oryza sativa)
Liliopsida Os.47398 35
Os02g0686600 35
  • 54.88 (n)
  • 52.87 (a)
wheat
(Triticum aestivum)
Liliopsida Ta.7612 35
bread mold
(Neurospora crassa)
Ascomycetes NCU03859 35
  • 57.64 (n)
  • 52.23 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC694.04c 35
  • 51.53 (n)
  • 50.33 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4262 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 47 (a)
OneToMany
CSA.2613 36
  • 49 (a)
OneToMany
Species with no ortholog for C12orf10:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for C12orf10 Gene

ENSEMBL:
Gene Tree for C12orf10 (if available)
TreeFam:
Gene Tree for C12orf10 (if available)

Paralogs for C12orf10 Gene

Selected SIMAP similar genes for C12orf10 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for C12orf10 Gene

genes like me logo Genes that share paralogs with C12orf10: view

No data available for Paralogs for C12orf10 Gene

Variants for C12orf10 Gene

Sequence variations from dbSNP and Humsavar for C12orf10 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1045181 -- 53,306,922(+) GAGAA(A/C/G)GCTGC intron-variant
rs1801674 -- 53,306,812(-) CCACT(G/T)TCCAG missense, reference
rs2030901 -- 53,304,349(+) GGCAC(A/G)ATCTC intron-variant
rs2279025 -- 53,305,709(+) GTGAT(C/G)TGAAT intron-variant
rs4325348 -- 53,305,201(-) TTGGA(C/T)CCCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C12orf10 Gene

Variant ID Type Subtype PubMed ID
nsv517066 CNV Loss 19592680

Relevant External Links for C12orf10 Gene

HapMap Linkage Disequilibrium report
C12orf10
Human Gene Mutation Database (HGMD)
C12orf10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C12orf10 Gene

Disorders for C12orf10 Gene

(2) University of Copenhagen DISEASES for C12orf10 Gene

Relevant External Links for C12orf10

Human Genome Epidemiology (HuGE) Navigator
C12orf10
genes like me logo Genes that share disorders with C12orf10: view

No data available for UniProtKB/Swiss-Prot for C12orf10 Gene

Publications for C12orf10 Gene

  1. Characterization of MYG1 gene and protein: subcellular distribution and function. (PMID: 19014353) Philips M.-A. … Nielsen F.C. (Biol. Cell 2009) 3 4 23
  2. Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1. (PMID: 20377893) Philips M.A. … KA/ks S. (BMC Med. Genet. 2010) 3 23
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3

Products for C12orf10 Gene

Sources for C12orf10 Gene

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