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Aliases for C11orf96 Gene

Aliases for C11orf96 Gene

  • Chromosome 11 Open Reading Frame 96 2 3 5
  • Protein Ag2 Homolog 3 4
  • AG2 3 4
  • Uncharacterized Protein C11orf96 3

External Ids for C11orf96 Gene

Previous GeneCards Identifiers for C11orf96 Gene

  • GC11P043673

Summaries for C11orf96 Gene

GeneCards Summary for C11orf96 Gene

C11orf96 (Chromosome 11 Open Reading Frame 96) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf96 Gene

Genomics for C11orf96 Gene

Regulatory Elements for C11orf96 Gene

Enhancers for C11orf96 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G043868 1.3 Ensembl ENCODE 10.6 -56.2 -56195 1.5 PKNOX1 CREB3L1 ARNT WRNIP1 YY1 ZNF766 CBX5 ZNF143 ZNF207 JUNB ALKBH3-AS1 C11orf96 HSD17B12 ALKBH3 MIR129-2 LOC105376644 ENSG00000283375
GH11G043946 1.1 ENCODE dbSUPER 11.8 +22.2 22156 1.3 HDAC1 CTCF ESRRA CBX3 RB1 ZIC2 RAD21 ZNF316 DIDO1 ZFHX2 C11orf96 ENSG00000254409 ALKBH3-AS1 LOC105376644 ALKBH3 ENSG00000244953 GC11P043987
GH11G044065 1.1 ENCODE 10 +141.1 141066 2.2 HDGF PKNOX1 CREB3L1 AGO1 SIN3A ZNF2 YY1 CBX5 ZNF143 ZNF207 ACCS EXT2 SEC14L1P1 ALKBH3 C11orf96 ALKBH3-AS1 ENSG00000255165
GH11G044037 0.9 ENCODE dbSUPER 10.9 +112.2 112174 0.2 CTCF ZNF654 RB1 NRF1 TRIM22 ZNF394 REST RAD21 NR2F2 JUND C11orf96 ALKBH3-AS1 ACCS GC11P043987
GH11G043962 0.8 ENCODE 11.5 +37.4 37425 1.0 LEF1 MAX CEBPG RAD21 YY1 IRF9 TRIM24 L3MBTL2 RNF2 CEBPB C11orf96 ALKBH3-AS1 ENSG00000254409 ENSG00000244953 GC11P043987
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf96 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf96 Gene

Chromosome:
11
Start:
43,925,342 bp from pter
End:
43,944,338 bp from pter
Size:
18,997 bases
Orientation:
Plus strand

Genomic View for C11orf96 Gene

Genes around C11orf96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf96 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf96 Gene

Proteins for C11orf96 Gene

  • Protein details for C11orf96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7L8-CK096_HUMAN
    Recommended name:
    Uncharacterized protein C11orf96
    Protein Accession:
    Q7Z7L8

    Protein attributes for C11orf96 Gene

    Size:
    435 amino acids
    Molecular mass:
    46114 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf96 Gene

Post-translational modifications for C11orf96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf96 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf96 Gene

Domains & Families for C11orf96 Gene

Protein Domains for C11orf96 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C11orf96 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf96: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C11orf96 Gene

Function for C11orf96 Gene

Phenotypes for C11orf96 Gene

GenomeRNAi human phenotypes for C11orf96:
genes like me logo Genes that share phenotypes with C11orf96: view

Animal Model Products

CRISPR Products

miRNA for C11orf96 Gene

miRTarBase miRNAs that target C11orf96

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf96 Gene

Localization for C11orf96 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf96 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf96 Gene

Pathways & Interactions for C11orf96 Gene

SuperPathways for C11orf96 Gene

No Data Available

Interacting Proteins for C11orf96 Gene

Gene Ontology (GO) - Biological Process for C11orf96 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf96 Gene

Drugs & Compounds for C11orf96 Gene

No Compound Related Data Available

Transcripts for C11orf96 Gene

mRNA/cDNA for C11orf96 Gene

Unigene Clusters for C11orf96 Gene

Chromosome 11 open reading frame 96:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf96 Gene

No ASD Table

Relevant External Links for C11orf96 Gene

GeneLoc Exon Structure for
C11orf96
ECgene alternative splicing isoforms for
C11orf96

Expression for C11orf96 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf96 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf96 Gene

This gene is overexpressed in Gallbladder (16.5), Liver, secretome (14.1), Heart (9.6), Testis (8.0), and Uterus (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf96 Gene



Protein tissue co-expression partners for C11orf96 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf96 Gene:

C11orf96

SOURCE GeneReport for Unigene cluster for C11orf96 Gene:

Hs.530443

Evidence on tissue expression from TISSUES for C11orf96 Gene

  • Lung(3)
  • Kidney(2.8)
genes like me logo Genes that share expression patterns with C11orf96: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf96 Gene

Orthologs for C11orf96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf96 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C15H11orf96 34
  • 96.42 (n)
mouse
(Mus musculus)
Mammalia Gm13889 34 16
  • 95.59 (n)
rat
(Rattus norvegicus)
Mammalia RGD1564664 34
  • 93.66 (n)
chicken
(Gallus gallus)
Aves C5H11ORF96 34
  • 85.28 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495977 34
  • 73.94 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100330987 34
  • 63.37 (n)
C25H11orf96 35
  • 54 (a)
OneToOne
Species where no ortholog for C11orf96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf96 Gene

ENSEMBL:
Gene Tree for C11orf96 (if available)
TreeFam:
Gene Tree for C11orf96 (if available)

Paralogs for C11orf96 Gene

No data available for Paralogs for C11orf96 Gene

Variants for C11orf96 Gene

Sequence variations from dbSNP and Humsavar for C11orf96 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001008053 -- 43,942,692(+) CCCCC(A/C)GAGCC intron-variant, utr-variant-5-prime
rs1001133985 -- 43,943,298(+) GGACG(-/CGCGCGTCCGCGGTC)CGCGC intron-variant, cds-indel
rs1001839895 -- 43,941,390(+) AGGAA(A/G)GTAAC intron-variant, upstream-variant-2KB
rs1002960909 -- 43,944,044(+) TGCGC(G/T)GGTCG intron-variant
rs1003222335 -- 43,943,814(+) ACGAT(A/C)TTTTT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C11orf96 Gene

Variant ID Type Subtype PubMed ID
dgv1109n100 CNV gain 25217958
esv3626156 CNV gain 21293372
nsv832138 CNV gain 17160897

Variation tolerance for C11orf96 Gene

Gene Damage Index Score: 8.43; 85.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf96 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf96 Gene

Disorders for C11orf96 Gene

Relevant External Links for C11orf96

Genetic Association Database (GAD)
C11orf96
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf96

No disorders were found for C11orf96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf96 Gene

Publications for C11orf96 Gene

  1. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
  2. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4 64
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for C11orf96 Gene

Sources for C11orf96 Gene

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