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Aliases for C11orf95 Gene

Aliases for C11orf95 Gene

  • Chromosome 11 Open Reading Frame 95 2 3

External Ids for C11orf95 Gene

Previous GeneCards Identifiers for C11orf95 Gene

  • GC11M063285
  • GC11M063527
  • GC11M059857

Summaries for C11orf95 Gene

GeneCards Summary for C11orf95 Gene

C11orf95 (Chromosome 11 Open Reading Frame 95) is a Protein Coding gene. Diseases associated with C11orf95 include ependymoma and chondroid lipoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf95 Gene

Genomics for C11orf95 Gene

Genomic Location for C11orf95 Gene

63,759,892 bp from pter
63,768,775 bp from pter
8,884 bases
Minus strand

Genomic View for C11orf95 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C11orf95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf95 Gene

No data available for Regulatory Elements for C11orf95 Gene

Proteins for C11orf95 Gene

  • Protein details for C11orf95 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf95
    Protein Accession:
    Secondary Accessions:
    • A6NLS7
    • Q3C1V4

    Protein attributes for C11orf95 Gene

    678 amino acids
    Molecular mass:
    73197 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAE46893.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for C11orf95 Gene

Proteomics data for C11orf95 Gene at MOPED

Post-translational modifications for C11orf95 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf95 Gene

No data available for DME Specific Peptides for C11orf95 Gene

Domains for C11orf95 Gene

Protein Domains for C11orf95 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf95: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf95 Gene

Function for C11orf95 Gene

miRNA for C11orf95 Gene

miRTarBase miRNAs that target C11orf95

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf95

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf95 Gene

Localization for C11orf95 Gene

Subcellular locations from

Jensen Localization Image for C11orf95 Gene COMPARTMENTS Subcellular localization image for C11orf95 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf95 Gene

Pathways for C11orf95 Gene

SuperPathways for C11orf95 Gene

No Data Available

Interacting Proteins for C11orf95 Gene

Gene Ontology (GO) - Biological Process for C11orf95 Gene


No data available for Pathways by source for C11orf95 Gene

Transcripts for C11orf95 Gene

mRNA/cDNA for C11orf95 Gene

(7) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf95 Gene

Chromosome 11 open reading frame 95:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf95

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf95 Gene

No ASD Table

Relevant External Links for C11orf95 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf95 Gene

mRNA expression in normal human tissues for C11orf95 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for C11orf95 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for C11orf95 Gene

SOURCE GeneReport for Unigene cluster for C11orf95 Gene Hs.191073

genes like me logo Genes that share expressions with C11orf95: view

Expression partners for C11orf95 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C11orf95 Gene

Orthologs for C11orf95 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf95 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C29H11orf95 35
  • 91.36 (n)
  • 87.37 (a)
(Canis familiaris)
Mammalia C18H11orf95 35
  • 88.51 (n)
  • 85.26 (a)
(Mus musculus)
Mammalia 2700081O15Rik 35
  • 88.18 (n)
  • 87.48 (a)
2700081O15Rik 16
(Pan troglodytes)
Mammalia C11H11orf95 35
  • 97.92 (n)
  • 96.79 (a)
(Rattus norvegicus)
Mammalia RGD1560108 35
  • 87.98 (n)
  • 87.56 (a)
Species with no ortholog for C11orf95:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf95 Gene

Gene Tree for C11orf95 (if available)
Gene Tree for C11orf95 (if available)

Paralogs for C11orf95 Gene

No data available for Paralogs for C11orf95 Gene

Variants for C11orf95 Gene

Sequence variations from dbSNP and Humsavar for C11orf95 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs537838272 -- 63,762,847(+) CCTGC(G/T)GCCCA utr-variant-3-prime
rs537354333 -- 63,767,729(+) CCCTG(A/C)AGCCG intron-variant
rs536758056 -- 63,764,643(+) GGCTG(C/G)GTTGC intron-variant
rs536440387 -- 63,763,862(+) AGCGG(A/G)ACGTC synonymous-codon, reference
rs536263364 -- 63,763,104(+) CGCTC(C/G)GCGCT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C11orf95 Gene

Variant ID Type Subtype PubMed ID
nsv832183 CNV Loss 17160897
esv33170 CNV Gain 17666407
esv24244 CNV Loss 19812545

Relevant External Links for C11orf95 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf95 Gene

Disorders for C11orf95 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for C11orf95 Gene in MalaCards »

(2) Diseases for C11orf95 Gene


  • Note=A chromosomal aberration involving MKL2 is found in 3 chondroid lipomas. Translocation t(11;16)(q13;p13) with MKL2 produces a C11orf95-MKL2 fusion protein (PubMed:20607705). {ECO:0000269 PubMed:20607705}.
  • Note=A chromosomal aberration involving RELA is found in more than two-thirds of supratentorial ependymomas. Translocation with RELA produces a C11orf95-RELA fusion protein. C11orf95-RELA translocations are potent oncogenes that probably transform neural stem cells by driving an aberrant NF-kappa-B transcription program (PubMed:24553141). {ECO:0000269 PubMed:24553141}.

(3) University of Copenhagen DISEASES for C11orf95 Gene

genes like me logo Genes that share disorders with C11orf95: view

No data available for OMIM , Novoseek inferred disease relationships , Genatlas and External Links for C11orf95 Gene

Publications for C11orf95 Gene

  1. C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. (PMID: 20607705) Huang D. … Bridge J.A. (Genes Chromosomes Cancer 2010) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-I_B signaling pathway. (PMID: 24562983) Pietsch T. … Klein-Hitpass L. (Acta Neuropathol. 2014) 3
  5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for C11orf95 Gene

Sources for C11orf95 Gene

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