C11orf92 Gene
protein-coding GIFtS: 35
GCID: GC11M111164
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chromosome 11 open reading frame 92
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Aliases
for C11orf92 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Chromosome 11 Open Reading Frame 921 2 | | FLJ458031 |
| External Ids: | HGNC: 337891 | Entrez Gene: 3999482 | Ensembl: ENSG000001961677 | UniProtKB: Q6ZS623 | | ORGUL members: | |
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| NONCODE:n409752 | |
Export aliases for C11orf92 gene to outside databasesPrevious GC identifers: GC11M110670 GC11M107090
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Summaries
for C11orf92 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C11orf92 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C11orf92 gene promoter:
c-Fos E2F-4 E2F-3a E2F-5 E2F-2 Nkx2-5 E2F-1 E2F Sox9 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for C11orf92
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf92 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.1 Ensembl cytogenetic band: 11q23.1 HGNC cytogenetic band: 11q23.1C11orf92 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M111164: view genomic region
(about GC identifiers)
Start:
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111,164,114 bp from pter |
End:
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111,175,770 bp from pter |
Size:
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11,657 bases |
Orientation:
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minus strand |
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Proteins
for C11orf92 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CK092_HUMAN, Q6ZS62 (See
protein sequence)Recommended Name: Uncharacterized protein C11orf92 Size: 124 amino acids; 13401 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)Explore the universe of human proteins at neXtProt for C11orf92: NX_Q6ZS62
C11orf92 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000437253 ENSP00000347601 ENSP00000438980
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
C11orf92 for ontologies About GeneDecksing
C11orf92 Antibody Products:
Assay Products for C11orf92: |
Protein
Domains /
Families
for C11orf92 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ZS62 |
Function
for C11orf92 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf92 |
|
Pathways & Interactions
for C11orf92 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C11orf92
|
Drugs & Compounds
for C11orf92 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C11orf92
Search CenterWatch for drugs/clinical trials and news about C11orf92 / CK092 
|
Transcripts
for C11orf92 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C11orf92 gene: NM_207429.2 Unigene Cluster for C11orf92: Chromosome 11 open reading frame 92 Hs.729225 [show with all ESTs]Unigene Representative Sequence: CR9367784 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000532918(uc001ple.3) ENST00000355430(uc001pld.3) ENST00000526150
ENST00000540738
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf92
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C11orf92 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf92 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf92 |
Additional cDNA sequence: AB096245.1 AK127703.1 CR936778.1 NR_034154.1 6 DOTS entries: DT.454859 DT.105142 DT.120712119 DT.86847428 DT.97834406 DT.91961785 24/43 AceView cDNA sequences (see all 43): AI806340 AW573293 CB241386 NM_207429 BX486062 AW661751 CA314483 BM853126 BF590585 AB096245 AW058265 CN478733 AK127703 BX486313 BM823942 CA437027 CF121410 BX097686 AI200281 AI149706 BX486061 BM795014 AI985511 BG291067
GeneLoc Exon Structure
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Expression
for C11orf92 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C11orf92 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGAAAATCT
About this image
See C11orf92 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C11orf92
SOURCE GeneReport for Unigene cluster: Hs.729225
SABiosciences Custom PCR Arrays for C11orf92
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf92
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C11orf92 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf92 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf92 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf92 |
Orthologs
for C11orf92 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C11orf92 gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
2010007H06Rik5 |
RIKEN cDNA 2010007H06 gene |
-- |
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9 (28.04 cM) 51280295 |
ENSEMBL Gene Tree for C11orf92 (if available)
TreeFam Gene Tree for C11orf92 (if available) |
Paralogs
for C11orf92 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C11orf92 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C11orf92 (111164114 - 111175770 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C11orf92: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for C11orf92 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C11orf92 for disorders About GeneDecksing
2  diseases for C11orf92: About MalaCardsfamilial colorectal cancer colorectal cancer
Human Genome Epidemiology (HuGE) Navigator: C11orf92 (0 documents)
Export disorders for C11orf92 gene to outside databases
|
Publications
for C11orf92 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C11orf92 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C11orf92) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Risk of genome-wide association study-identified gene tic variants for colorectal cancer in a Chinese population. (PubMed id 20530476)1 Xiong F....Lin D. (2010)
- Susceptibility genetic variants associated with color ectal cancer risk correlate with cancer phenotype. (PubMed id 20638935)1 AbulA- A....Andreu M. (2010)
- Association studies on 11 published colorectal cancer risk loci. (PubMed id 20648012)1 von Holst S....Lindblom A. (2010)
- Low-penetrance susceptibility variants in familial co lorectal cancer. (PubMed id 20501757)1 NiittymAoki I....Aaltonen L.A. (2010)
- Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort. (PubMed id 19843678)1 Middeldorp A....van Wezel T. (2009)
- Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. (PubMed id 18753146)1 Pittman A.M....Houlston R.S. (2008)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for C11orf92 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C11orf92 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C11orf92 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C11orf92 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C11orf92 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C11orf92 gene:
Search GeneIP for patents involving C11orf92
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C11orf92 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C11orf92 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C11orf92 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf92 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C11orf92 | | OriGene 3'-UTR Clone for C11orf92 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf92 | | Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C11orf92 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf92 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf92 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C11orf92 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf92 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf92 |
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 | | | C11orf92 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf92 |
|  |  |  | | | | Search ThermoFisher Antibodies for C11orf92 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C11orf92 |
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