Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C11orf87 Gene

Aliases for C11orf87 Gene

  • Chromosome 11 Open Reading Frame 87 2 3 5
  • Neuronal Integral Membrane Protein 1 2 3
  • Uncharacterized Protein C11orf87 3
  • LOH11CR1A 3
  • NEURIM1 3

External Ids for C11orf87 Gene

Previous GeneCards Identifiers for C11orf87 Gene

  • GC11P108799
  • GC11P109292
  • GC11P105218

Summaries for C11orf87 Gene

GeneCards Summary for C11orf87 Gene

C11orf87 (Chromosome 11 Open Reading Frame 87) is a Protein Coding gene.

Additional gene information for C11orf87 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf87 Gene

Genomics for C11orf87 Gene

Regulatory Elements for C11orf87 Gene

Enhancers for C11orf87 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H109421 0.3 FANTOM5 9.4 -0.4 -407 0 C11orf87 ENSG00000264997 GC11M109264
GH11H109695 0.6 ENCODE 4.7 +274.6 274623 2 CTCF ZNF654 JUND SMC3 ZNF143 REST RAD21 ZNF507 ZC3H12C C11orf87 CCT6P5 LOC105369482
GH11H109604 0.2 ENCODE 6.8 +183.5 183483 0 C11orf87 PIR75450 CCT6P5
GH11H109618 0.2 ENCODE 6 +197.9 197923 1 C11orf87 PIR75450 CCT6P5
GH11H109320 0.4 ENCODE 0.1 -101.0 -100960 0 JUND POLR2A GC11M109264 ENSG00000264997 C11orf87
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf87 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf87 Gene

Chromosome:
11
Start:
109,421,728 bp from pter
End:
109,429,167 bp from pter
Size:
7,440 bases
Orientation:
Plus strand

Genomic View for C11orf87 Gene

Genes around C11orf87 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf87 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf87 Gene

Proteins for C11orf87 Gene

  • Protein details for C11orf87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NUJ2-CK087_HUMAN
    Recommended name:
    Uncharacterized protein C11orf87
    Protein Accession:
    Q6NUJ2
    Secondary Accessions:
    • B4E169

    Protein attributes for C11orf87 Gene

    Size:
    197 amino acids
    Molecular mass:
    20623 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf87 Gene

Post-translational modifications for C11orf87 Gene

Other Protein References for C11orf87 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf87 Gene

Domains & Families for C11orf87 Gene

Gene Families for C11orf87 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for C11orf87 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf87: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf87 Gene

Function for C11orf87 Gene

Phenotypes From GWAS Catalog for C11orf87 Gene

Gene Ontology (GO) - Molecular Function for C11orf87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C11orf87: view
genes like me logo Genes that share phenotypes with C11orf87: view

Animal Model Products

CRISPR Products

miRNA for C11orf87 Gene

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf87
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf87 Gene

Localization for C11orf87 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C11orf87 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf87 gene
Compartment Confidence
mitochondrion 2
plasma membrane 1
extracellular 1
nucleus 1
cytosol 1
lysosome 1

Gene Ontology (GO) - Cellular Components for C11orf87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C11orf87: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for C11orf87 Gene

Pathways & Interactions for C11orf87 Gene

SuperPathways for C11orf87 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C11orf87 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf87 Gene

Drugs & Compounds for C11orf87 Gene

No Compound Related Data Available

Transcripts for C11orf87 Gene

mRNA/cDNA for C11orf87 Gene

Unigene Clusters for C11orf87 Gene

Chromosome 11 open reading frame 87:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf87
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf87 Gene

No ASD Table

Relevant External Links for C11orf87 Gene

GeneLoc Exon Structure for
C11orf87
ECgene alternative splicing isoforms for
C11orf87

Expression for C11orf87 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf87 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C11orf87 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x10.6), Brain - Anterior cingulate cortex (BA24) (x8.9), and Brain - Cortex (x8.9).

NURSA nuclear receptor signaling pathways regulating expression of C11orf87 Gene:

C11orf87

SOURCE GeneReport for Unigene cluster for C11orf87 Gene:

Hs.172982

Evidence on tissue expression from TISSUES for C11orf87 Gene

  • Nervous system(4.7)
  • Kidney(4.1)
genes like me logo Genes that share expression patterns with C11orf87: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf87 Gene

Orthologs for C11orf87 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf87 33
  • 99.15 (n)
C11orf87 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C5H11orf87 33
  • 91.19 (n)
C11orf87 34
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100125362 33
  • 89.12 (n)
mouse
(Mus musculus)
Mammalia AI593442 33 16 34
  • 87.41 (n)
cow
(Bos Taurus)
Mammalia LOC617737 33
  • 86.28 (n)
C11orf87 34
  • 85 (a)
OneToOne
chicken
(Gallus gallus)
Aves C1H11ORF87 33
  • 76.06 (n)
C11orf87 34
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C11orf87 34
  • 61 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkey-35i13.1 33
  • 69.38 (n)
C15H11orf87 34
  • 46 (a)
OneToOne
Species where no ortholog for C11orf87 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf87 Gene

ENSEMBL:
Gene Tree for C11orf87 (if available)
TreeFam:
Gene Tree for C11orf87 (if available)

Paralogs for C11orf87 Gene

No data available for Paralogs for C11orf87 Gene

Variants for C11orf87 Gene

Sequence variations from dbSNP and Humsavar for C11orf87 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000180961 -- 109,426,363(+) GAAAC(A/G)TTACC utr-variant-3-prime
rs1000443924 -- 109,422,170(+) GCGCG(C/G)CTCGG upstream-variant-2KB, utr-variant-5-prime
rs1000587406 -- 109,428,517(+) GGTTA(A/T)AGTAG utr-variant-3-prime
rs1000636210 -- 109,426,699(+) CTGTG(A/C)AGAAG utr-variant-3-prime
rs1000641558 -- 109,422,150(+) CGGCG(A/G)CGGCG upstream-variant-2KB, utr-variant-5-prime

Variation tolerance for C11orf87 Gene

Residual Variation Intolerance Score: 49.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.02; 20.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf87 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C11orf87 Gene

Disorders for C11orf87 Gene

Relevant External Links for C11orf87

Genetic Association Database (GAD)
C11orf87
Human Genome Epidemiology (HuGE) Navigator
C11orf87
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf87

No disorders were found for C11orf87 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf87 Gene

Publications for C11orf87 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) Schizophrenia Working Group of the Psychiatric Genomics Consortium (Nature 2014) 3 60
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 60
  5. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M … Gstaiger M (Cell reports 2013) 3 60

Products for C11orf87 Gene

Sources for C11orf87 Gene

Content
Loading form....