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Aliases for C11orf86 Gene

Aliases for C11orf86 Gene

  • Chromosome 11 Open Reading Frame 86 2 3 5

External Ids for C11orf86 Gene

Previous GeneCards Identifiers for C11orf86 Gene

  • GC11P066504
  • GC11P066742
  • GC11P063070

Summaries for C11orf86 Gene

GeneCards Summary for C11orf86 Gene

C11orf86 (Chromosome 11 Open Reading Frame 86) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf86 Gene

Genomics for C11orf86 Gene

Regulatory Elements for C11orf86 Gene

Enhancers for C11orf86 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F066903 0.9 Ensembl ENCODE 10.9 -68.6 -68645 5.6 ARID4B DMAP1 YY1 FOS SP5 NFYC PPARG ZNF623 MAFF ZSCAN16 PC C11orf80 RHOD ACTN3 CTSF RIN1 C11orf86 LRFN4 SYT12 LOC100505504
GH11F066973 1.3 Ensembl ENCODE 0.8 -0.2 -249 3.1 ARID4B SIN3A RAD21 RCOR1 DEK SMARCA5 ZNF654 CEBPB REST GLIS1 DPP3 SPTBN2 C11orf86 PC
GH11F066974 0.2 ENCODE 0.8 -2.1 -2099 0.0 ZBTB33 RNU7-23P C11orf86 PC
GH11F066981 0.9 Ensembl ENCODE 0.4 +6.8 6824 1.4 PKNOX1 RAD21 RFX5 GTF3C2 ZNF366 SCRT2 RCOR1 FOS SMARCC1 ZNF362 EIF1AD ENSG00000258297 RAD9A RBM14 RCE1 BRMS1 DPP3 ENSG00000245156 MRPL11 CORO1B
GH11F066983 0.8 Ensembl ENCODE 0.4 +9.0 9024 1.4 ESRRA CBX3 PKNOX1 ZFHX2 ZNF316 CTBP1 TRIM24 MAFK EGR2 ZNF687 RHOD C11orf86 SYT12
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C11orf86 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf86 Gene

66,975,277 bp from pter
66,977,008 bp from pter
1,732 bases
Plus strand

Genomic View for C11orf86 Gene

Genes around C11orf86 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf86 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf86 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf86 Gene

Proteins for C11orf86 Gene

  • Protein details for C11orf86 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf86
    Protein Accession:

    Protein attributes for C11orf86 Gene

    115 amino acids
    Molecular mass:
    13172 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf86 Gene

Post-translational modifications for C11orf86 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf86 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf86 Gene

Domains & Families for C11orf86 Gene

Protein Domains for C11orf86 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf86: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf86 Gene

Function for C11orf86 Gene

Phenotypes for C11orf86 Gene

genes like me logo Genes that share phenotypes with C11orf86: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf86 Gene

Localization for C11orf86 Gene

Subcellular locations from

Jensen Localization Image for C11orf86 Gene COMPARTMENTS Subcellular localization image for C11orf86 gene
Compartment Confidence
nucleus 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf86 Gene

Pathways & Interactions for C11orf86 Gene

SuperPathways for C11orf86 Gene

No Data Available

Interacting Proteins for C11orf86 Gene

Gene Ontology (GO) - Biological Process for C11orf86 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf86 Gene

Transcripts for C11orf86 Gene

mRNA/cDNA for C11orf86 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf86 Gene

Chromosome 11 open reading frame 86:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf86 Gene

ExUns: 1a · 1b ^ 2a · 2b

Relevant External Links for C11orf86 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf86 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf86 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf86 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x33.8) and Colon - Transverse (x12.3).

NURSA nuclear receptor signaling pathways regulating expression of C11orf86 Gene:


SOURCE GeneReport for Unigene cluster for C11orf86 Gene:

genes like me logo Genes that share expression patterns with C11orf86: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C11orf86 Gene

Orthologs for C11orf86 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf86 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C11H11orf86 34
  • 100 (n)
C11orf86 35
  • 100 (a)
(Bos Taurus)
Mammalia C29H11orf86 34 35
  • 81.12 (n)
(Mus musculus)
Mammalia 2010003K11Rik 34 16 35
  • 80.12 (n)
(Canis familiaris)
Mammalia C18H11orf86 34
  • 79.94 (n)
C11ORF86 35
  • 65 (a)
(Rattus norvegicus)
Mammalia LOC689065 34
  • 78.95 (n)
(Monodelphis domestica)
Mammalia C11orf86 35
  • 53 (a)
Species where no ortholog for C11orf86 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf86 Gene

Gene Tree for C11orf86 (if available)
Gene Tree for C11orf86 (if available)

Paralogs for C11orf86 Gene

No data available for Paralogs for C11orf86 Gene

Variants for C11orf86 Gene

Sequence variations from dbSNP and Humsavar for C11orf86 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs111377270 -- 66,973,562(+) TGTTG(A/C)CCAGG upstream-variant-2KB
rs112883990 -- 66,974,615(+) TCACT(C/G)CAACC upstream-variant-2KB
rs114582356 -- 66,973,506(+) TACAC(C/T)TGGAT upstream-variant-2KB
rs115097903 -- 66,977,133(+) CGGGG(C/T)GGGCT downstream-variant-500B
rs115549800 -- 66,974,146(+) AATGA(A/G)GCTAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for C11orf86 Gene

Variant ID Type Subtype PubMed ID
nsv555226 CNV gain 21841781
nsv832194 CNV gain+loss 17160897

Variation tolerance for C11orf86 Gene

Gene Damage Index Score: 1.69; 32.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf86 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf86 Gene

Disorders for C11orf86 Gene

Relevant External Links for C11orf86

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C11orf86 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf86 Gene

Publications for C11orf86 Gene

  1. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3 64
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for C11orf86 Gene

Sources for C11orf86 Gene

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