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Aliases for C11orf84 Gene

Aliases for C11orf84 Gene

  • Chromosome 11 Open Reading Frame 84 2 3 5

External Ids for C11orf84 Gene

Previous GeneCards Identifiers for C11orf84 Gene

  • GC11P063338
  • GC11P063581
  • GC11P059909

Summaries for C11orf84 Gene

GeneCards Summary for C11orf84 Gene

C11orf84 (Chromosome 11 Open Reading Frame 84) is a Protein Coding gene.

Additional gene information for C11orf84 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf84 Gene

Genomics for C11orf84 Gene

Regulatory Elements for C11orf84 Gene

Enhancers for C11orf84 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H062838 1.5 ENCODE dbSUPER 18 -972.5 -972529 4.8 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 ZC3H11A NFYC UBXN1 METTL12 WDR74 NXF1 SNHG1 INTS5 LOC105369332 STX5 MTA2 GANAB
GH11H063813 1 ENCODE 26.3 +0.3 348 2.2 ZFP64 ARID4B SIN3A DMAP1 ZNF121 GLIS2 RUNX3 SP3 NFYC ZNF592 C11orf84 PIR56042
GH11H063665 1.3 ENCODE dbSUPER 13.7 -144.3 -144276 6.6 HDGF SIN3A YY1 ZNF766 CBX5 ZNF207 ZNF143 FOS DEK REST ATL3 C11orf84 IMMP1LP1 TRMT112 TAF6L TTC9C PLA2G16 GC11P063651 PIR31666
GH11H064267 1.4 ENCODE dbSUPER 12.7 +457.3 457326 7.2 DMAP1 YY1 SLC30A9 ZNF143 SP3 MCM3 NFYC MEF2D SSRP1 ZNF585B ZFPL1 SF1 POLA2 PLCB3 ENSG00000257086 TRMT112 DNAJC4 FAU LOC102723878 TRPT1
GH11H063865 1.6 Ensembl ENCODE dbSUPER 11.1 +57.0 57001 9.8 HDGF FOXA2 PKNOX1 ARID4B SIN3A FEZF1 YY1 SLC30A9 ZNF143 FOS NAA40 MARK2 C11orf84 RTN3 PLA2G16 LOC105369340 GC11M063862 RNU6-1306P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf84 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf84 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000040570 426 1601 ZFP64 ARID4B SIN3A DMAP1 ZNF121 GLIS2 RUNX3 SP3 NFYC ZNF592

Genomic Locations for C11orf84 Gene

Genomic Locations for C11orf84 Gene
14,345 bases
Plus strand

Genomic View for C11orf84 Gene

Genes around C11orf84 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf84 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf84 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf84 Gene

Proteins for C11orf84 Gene

  • Protein details for C11orf84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf84
    Protein Accession:
    Secondary Accessions:
    • Q68CV7
    • Q6PHS2
    • Q96IH0

    Protein attributes for C11orf84 Gene

    381 amino acids
    Molecular mass:
    41037 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf84 Gene

Post-translational modifications for C11orf84 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C11orf84 Gene

Domains & Families for C11orf84 Gene

Gene Families for C11orf84 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf84 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf84: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf84 Gene

Function for C11orf84 Gene

Phenotypes From GWAS Catalog for C11orf84 Gene

genes like me logo Genes that share phenotypes with C11orf84: view

miRNA for C11orf84 Gene

miRTarBase miRNAs that target C11orf84

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf84 Gene

Localization for C11orf84 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf84 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf84 Gene

Pathways & Interactions for C11orf84 Gene

SuperPathways for C11orf84 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C11orf84 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf84 Gene

Drugs & Compounds for C11orf84 Gene

No Compound Related Data Available

Transcripts for C11orf84 Gene

Unigene Clusters for C11orf84 Gene

Chromosome 11 open reading frame 84:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf84 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6
SP1: -
SP3: - -

Relevant External Links for C11orf84 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf84 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf84 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf84 Gene

This gene is overexpressed in Cervix (60.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C11orf84 Gene

Protein tissue co-expression partners for C11orf84 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf84 Gene:


SOURCE GeneReport for Unigene cluster for C11orf84 Gene:

genes like me logo Genes that share expression patterns with C11orf84: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf84 Gene

Orthologs for C11orf84 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf84 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C11H11orf84 33
  • 97.89 (n)
C11orf84 34
  • 97 (a)
(Canis familiaris)
Mammalia C11orf84 34
  • 89 (a)
C18H11orf84 33
  • 88.07 (n)
(Bos Taurus)
Mammalia C29H11orf84 33 34
  • 85.24 (n)
(Rattus norvegicus)
Mammalia RGD1308106 33
  • 82.12 (n)
(Mus musculus)
Mammalia AI846148 33 16 34
  • 82.02 (n)
(Monodelphis domestica)
Mammalia C11orf84 34
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia C11orf84 34
  • 48 (a)
Species where no ortholog for C11orf84 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf84 Gene

Gene Tree for C11orf84 (if available)
Gene Tree for C11orf84 (if available)

Paralogs for C11orf84 Gene

No data available for Paralogs for C11orf84 Gene

Variants for C11orf84 Gene

Sequence variations from dbSNP and Humsavar for C11orf84 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000102900 -- 63,827,008(+) GCCTC(C/G)TGCAA nc-transcript-variant, reference, synonymous-codon, missense
rs1000217433 -- 63,827,557(+) TGTTC(A/G)GGCTT nc-transcript-variant, utr-variant-3-prime
rs1000257230 -- 63,827,605(+) CCCCT(G/T)CAGAG nc-transcript-variant, utr-variant-3-prime
rs1000331990 -- 63,817,035(+) AGCTG(A/G)GTGTG intron-variant
rs1000514052 -- 63,815,358(+) TTCAA(C/G)GTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf84 Gene

Variant ID Type Subtype PubMed ID
nsv555180 CNV loss 21841781
esv33730 CNV gain 17666407

Variation tolerance for C11orf84 Gene

Residual Variation Intolerance Score: 88.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.12; 38.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf84 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf84 Gene

Disorders for C11orf84 Gene

Relevant External Links for C11orf84

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C11orf84 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf84 Gene

Publications for C11orf84 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  2. Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. (PMID: 28162770) Wang T … Sabatini DM (Cell 2017) 3 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  5. Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon. (PMID: 26990986) Nguyen TV … Deshaies RJ (Molecular cell 2016) 3 60

Products for C11orf84 Gene

Sources for C11orf84 Gene

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