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Aliases for C11orf84 Gene

Aliases for C11orf84 Gene

  • Chromosome 11 Open Reading Frame 84 2 3 5

External Ids for C11orf84 Gene

Previous GeneCards Identifiers for C11orf84 Gene

  • GC11P063338
  • GC11P063581
  • GC11P059909

Summaries for C11orf84 Gene

GeneCards Summary for C11orf84 Gene

C11orf84 (Chromosome 11 Open Reading Frame 84) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf84 Gene

Genomics for C11orf84 Gene

Regulatory Elements for C11orf84 Gene

Enhancers for C11orf84 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C11orf84 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf84 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C11orf84 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf84 Gene

Chromosome:
11
Start:
63,813,374 bp from pter
End:
63,827,718 bp from pter
Size:
14,345 bases
Orientation:
Plus strand

Genomic View for C11orf84 Gene

Genes around C11orf84 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf84 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf84 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf84 Gene

Proteins for C11orf84 Gene

  • Protein details for C11orf84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUA3-CK084_HUMAN
    Recommended name:
    Uncharacterized protein C11orf84
    Protein Accession:
    Q9BUA3
    Secondary Accessions:
    • Q68CV7
    • Q6PHS2
    • Q96IH0

    Protein attributes for C11orf84 Gene

    Size:
    381 amino acids
    Molecular mass:
    41037 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf84 Gene

Proteomics data for C11orf84 Gene at MOPED

Post-translational modifications for C11orf84 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf84 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf84 Gene

Domains & Families for C11orf84 Gene

Protein Domains for C11orf84 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf84: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf84 Gene

Function for C11orf84 Gene

genes like me logo Genes that share phenotypes with C11orf84: view

Animal Model Products

CRISPR Products

miRNA for C11orf84 Gene

miRTarBase miRNAs that target C11orf84

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf84 Gene

Localization for C11orf84 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C11orf84 Gene COMPARTMENTS Subcellular localization image for C11orf84 gene
Compartment Confidence
nucleus 4
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf84 Gene

Pathways & Interactions for C11orf84 Gene

SuperPathways for C11orf84 Gene

No Data Available

Interacting Proteins for C11orf84 Gene

Gene Ontology (GO) - Biological Process for C11orf84 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf84 Gene

Drugs & Compounds for C11orf84 Gene

No Compound Related Data Available

Transcripts for C11orf84 Gene

Unigene Clusters for C11orf84 Gene

Chromosome 11 open reading frame 84:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf84 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6
SP1: -
SP2:
SP3: - -

Relevant External Links for C11orf84 Gene

GeneLoc Exon Structure for
C11orf84
ECgene alternative splicing isoforms for
C11orf84

Expression for C11orf84 Gene

mRNA expression in normal human tissues for C11orf84 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf84 Gene

This gene is overexpressed in Cervix (60.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C11orf84 Gene



SOURCE GeneReport for Unigene cluster for C11orf84 Gene Hs.502793

genes like me logo Genes that share expression patterns with C11orf84: view

Protein tissue co-expression partners for C11orf84 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C11orf84 Gene

Orthologs for C11orf84 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf84 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C29H11orf84 35
  • 85.24 (n)
  • 83.2 (a)
C29H11orf84 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C18H11orf84 35
  • 88.07 (n)
  • 87.89 (a)
C11orf84 36
  • 89 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf84 35
  • 97.89 (n)
  • 97.99 (a)
C11orf84 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1308106 35
  • 82.12 (n)
  • 82.75 (a)
mouse
(Mus musculus)
Mammalia AI846148 16
AI846148 36
  • 82 (a)
OneToOne
AI846148 35
  • 82.02 (n)
  • 82.63 (a)
oppossum
(Monodelphis domestica)
Mammalia C11orf84 36
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C11orf84 36
  • 48 (a)
OneToOne
Species with no ortholog for C11orf84:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf84 Gene

ENSEMBL:
Gene Tree for C11orf84 (if available)
TreeFam:
Gene Tree for C11orf84 (if available)

Paralogs for C11orf84 Gene

No data available for Paralogs for C11orf84 Gene

Variants for C11orf84 Gene

Sequence variations from dbSNP and Humsavar for C11orf84 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs35875163 - 63,817,849(+) CGCTA(C/G)AGGCA reference, missense
rs558654 -- 63,815,806(+) ctttt(G/T)gccca intron-variant
rs612010 -- 63,823,533(+) GAGGA(A/G)GTGGG intron-variant, downstream-variant-500B
rs623444 -- 63,821,197(+) CTTGC(C/T)CAGCT intron-variant
rs626333 -- 63,824,389(+) ACGTC(A/G)TATCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf84 Gene

Variant ID Type Subtype PubMed ID
esv33730 CNV Gain 17666407

Variation tolerance for C11orf84 Gene

Residual Variation Intolerance Score: 88.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.12; 38.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf84 Gene

HapMap Linkage Disequilibrium report
C11orf84

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf84 Gene

Disorders for C11orf84 Gene

Relevant External Links for C11orf84

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf84

No disorders were found for C11orf84 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf84 Gene

Publications for C11orf84 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. BioID-based Identification of Skp Cullin F-box (SCF)I^-TrCP1/2 E3 Ligase Substrates. (PMID: 25900982) Coyaud E. … Raught B. (Mol. Cell Proteomics 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy. (PMID: 26460568) Johnson-Kerner B.L. … Wichterle H. (PLoS ONE 2015) 3
  5. Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event. (PMID: 26527279) Campos E.I. … Reinberg D. (Mol. Cell 2015) 3

Products for C11orf84 Gene

Sources for C11orf84 Gene

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