C11orf84 Gene
protein-coding GIFtS: 38
GCID: GC11P063581 (predicted)
|
|
chromosome 11 open reading frame 84
| |
Aliases
for C11orf84 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 11 Open Reading Frame 841 2 | | Hypothetical Protein BC0075402 | | Uncharacterized Protein C11orf842 |
Export aliases for C11orf84 gene to outside databasesPrevious GC identifers: GC11P063338 GC11P059909 |
Summaries
for C11orf84 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C11orf84 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C11orf84 gene promoter:
USF1 Elk-1 USF2 USF-1:USF-2 E47 CREB PPAR-gamma1 deltaCREB USF-1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for C11orf84
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf84 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.1 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13.1C11orf84 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P063581: view genomic region
(about GC identifiers)
Start:
|
63,580,860 bp from pter |
End:
|
63,595,190 bp from pter |
Size:
|
14,331 bases |
Orientation:
|
plus strand |
|
Proteins
for C11orf84 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CK084_HUMAN, Q9BUA3 (See
protein sequence)Recommended Name: Uncharacterized protein C11orf84 Size: 381 amino acids; 41037 Da
Secondary accessions: Q68CV7 Q6PHS2 Q96IH0Explore the universe of human proteins at neXtProt for C11orf84: NX_Q9BUA3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BUA3
C11orf84 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_612480.1
ENSEMBL proteins: ENSP00000294244 ENSP00000445256 ENSP00000443715
Human Recombinant Protein Products:
C11orf84 Antibody Products:
Assay Products for C11orf84: |
Protein
Domains /
Families
for C11orf84 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9BUA3 |
Function
for C11orf84 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C11orf84 (NM_138471) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf84 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf84 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf84 |
|
Pathways & Interactions
for C11orf84 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C11orf84
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for C11orf84 (Q9BUA33 ENSP000002942444) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C11orf84 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C11orf84
Search CenterWatch for drugs/clinical trials and news about C11orf84 / CK084
|
Transcripts
for C11orf84 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C11orf84 gene: NM_138471.1 Unigene Cluster for C11orf84: Chromosome 11 open reading frame 84 Hs.502793 [show with all ESTs]Unigene Representative Sequence: AK0914933 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000294244(uc001nxt.3) ENST00000540893 ENST00000535820
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C11orf84 (NM_138471) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf84 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf84 |
Additional cDNA sequence: AK091493.1 AK092098.1 BC002782.2 BC007540.1 BC056402.1 CR749697.1 9 DOTS entries: DT.409823 DT.100761028 DT.100776062 DT.40114613 DT.65287857 DT.91759675 DT.91759676 DT.95160771 DT.95126734 24/109 AceView cDNA sequences (see all 109): AA678817 CR622295 BM903854 CA976178 BC007540 AA643577 CR602254 AW272855 BQ071899 BU619979 BC002782 CR749697 CR597472 BQ009932 AA723034 BX397628 BE256102 CA439568 BM926119 AI612823 BM925859 BM470890 AL525102 BX393946
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for C11orf84 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for C11orf84
|
Expression
for C11orf84 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C11orf84 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See C11orf84 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C11orf84
SOURCE GeneReport for Unigene cluster: Hs.502793
SABiosciences Custom PCR Arrays for C11orf84
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf84
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C11orf84 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf84 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf84 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf84 |
Orthologs
for C11orf84 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C11orf84 gene from 1/7 species (see all 7) About this table
ENSEMBL Gene Tree for C11orf84 (if available)
TreeFam Gene Tree for C11orf84 (if available) |
Paralogs
for C11orf84 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C11orf84 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C11orf84 (63580860 - 63595190 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C11orf84
1 CNV: 6933 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf84 |
|
Disorders
/ Diseases
for C11orf84 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C11orf84 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C11orf84 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with C11orf84) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6. (PubMed id 22554406)1 Kang S.J....Porjesz B. (2012)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
- Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
- Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor. (PubMed id 18271526)1 Tong J....Moran M.F. (2008)
|
External Searches for C11orf84 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C11orf84 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C11orf84 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C11orf84 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C11orf84 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C11orf84 gene:
Search GeneIP for patents involving C11orf84
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C11orf84 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C11orf84 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C11orf84 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf84 | | | OriGene Protein Over-expression Lysate for C11orf84 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for C11orf84 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf84 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C11orf84 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C11orf84 | | OriGene Custom Protein Services for C11orf84 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C11orf84 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf84 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf84 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C11orf84 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf84 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf84 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | C11orf84 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf84 |
|  |  |  | | | | Search ThermoFisher Antibodies for C11orf84 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf84 |
|
|
|
|
