Aliases for C11orf80 Gene
External Ids for C11orf80 Gene
Previous GeneCards Identifiers for C11orf80 Gene
GeneCards Summary for C11orf80 Gene
C11orf80 (Chromosome 11 Open Reading Frame 80) is a Protein Coding gene.
UniProtKB/Swiss-Prot for C11orf80 Gene
Isoform 3: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.