C11orf80 Gene
protein-coding GIFtS: 38
GCID: GC11P066512
|
|
chromosome 11 open reading frame 80
| |
Aliases
for C11orf80 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 11 Open Reading Frame 801 2 | | FLJ225311 | | Putative Uncharacterized Protein C11orf802 |
Export aliases for C11orf80 gene to outside databasesPrevious GC identifers: GC11P066269 GC11P062840 |
Summaries
for C11orf80 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C11orf80 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C11orf80 gene promoter:
GR Spz1 AP-4 LCR-F1 AP-2beta Sox9 GR-alpha AP-2alpha AP-2alphaA RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for C11orf80
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf80 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.2 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.2C11orf80 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P066512: view genomic region
(about GC identifiers)
Start:
|
66,511,922 bp from pter |
End:
|
66,610,987 bp from pter |
Size:
|
99,066 bases |
Orientation:
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plus strand |
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Proteins
for C11orf80 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CK080_HUMAN, Q8N6T0 (See
protein sequence)Recommended Name: Putative uncharacterized protein C11orf80 Size: 522 amino acids; 58062 Da
Secondary accessions: Q9H677Alternative splicing: 2 isoforms: Q8N6T0-1 Q8N6T0-2 Explore the universe of human proteins at neXtProt for C11orf80: NX_Q8N6T0
C11orf80 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_078926.3
ENSEMBL proteins: ENSP00000437319 ENSP00000434960 ENSP00000432039 ENSP00000431578 ENSP00000433447 ENSP00000437143 ENSP00000434804 ENSP00000434648 ENSP00000435512 ENSP00000433869 ENSP00000432775 ENSP00000433032 ENSP00000354227 ENSP00000317408 ENSP00000444319
Human Recombinant Protein Products for C11orf80:
C11orf80 Antibody Products:
Assay Products for C11orf80: |
Protein
Domains /
Families
for C11orf80 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8N6T0 |
Function
for C11orf80 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C11orf80 (NM_024650) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf80 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf80 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf80 |
|
Pathways & Interactions
for C11orf80 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C11orf80
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for C11orf80 (Q8N6T03 ENSP000003542274) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C11orf80 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C11orf80
Search CenterWatch for drugs/clinical trials and news about C11orf80 / CK080
|
Transcripts
for C11orf80 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C11orf80 gene: NM_024650.3 Unigene Cluster for C11orf80: Chromosome 11 open reading frame 80 Hs.292088 [show with all ESTs]Unigene Representative Sequence: NM_02465018/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000534325 ENST00000524551 ENST00000525908 ENST00000527634 ENST00000527368
ENST00000528340 ENST00000531400 ENST00000532565 ENST00000525449 ENST00000532727
ENST00000532089 ENST00000526260 ENST00000527352 ENST00000533143 ENST00000526718
ENST00000531415 ENST00000526270 ENST00000360962(uc021qmd.1 uc010rpl.2 uc001ojj.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C11orf80 (NM_024650) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf80 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf80 |
Additional cDNA sequence: AK026184.1 AK225435.1 AK302025.1 BC028240.1 NR_048553.1 15 DOTS entries: DT.441833 DT.97845283 DT.97845282 DT.430291 DT.100785433 DT.95273956 DT.99972836 DT.91857956 DT.92437820 DT.95273957 DT.100785429 DT.100843086 DT.40221608 DT.92437817 DT.95148582 24/222 AceView cDNA sequences (see all 222): BE856459 BP371215 AA639800 CB850516 AL547398 BF436853 BX107454 AK026184 BX109301 BM554707 BU543442 AL713740 AA593730 AI289771 BM928167 AA428315 BM701935 BF000305 AL537953 CR602609 AA470901 BG576427 BE219024 BF001690
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for C11orf80 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
|---|
|
| SP1: | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C11orf80
|
Expression
for C11orf80 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C11orf80 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAGGTGAAG
About this image
See C11orf80 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C11orf80
SOURCE GeneReport for Unigene cluster: Hs.292088
SABiosciences Custom PCR Arrays for C11orf80
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf80
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C11orf80 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf80 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf80 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf80 |
Orthologs
for C11orf80 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C11orf80 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for C11orf80 (if available)
TreeFam Gene Tree for C11orf80 (if available) |
Paralogs
for C11orf80 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C11orf80 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C11orf80 (66511922 - 66610987 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C11orf80
1 CNV: 48872 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf80 |
|
Disorders
/ Diseases
for C11orf80 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C11orf80 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C11orf80 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C11orf80) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The molecular basis of the folate-sensitive fragile site FRA11A at 11q13. (PubMed id 18160775)1, 3 Debacker K....Kooy F. (2007)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for C11orf80 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C11orf80 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C11orf80 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C11orf80 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C11orf80 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C11orf80 gene:
Search GeneIP for patents involving C11orf80
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C11orf80 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C11orf80 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C11orf80 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf80 | | | OriGene Protein Over-expression Lysate for C11orf80 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C11orf80 | | OriGene 3'-UTR Clone for C11orf80 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf80 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C11orf80 | | OriGene Custom Protein Services for C11orf80 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C11orf80 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf80 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf80 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C11orf80 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf80 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf80 |
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 | | | C11orf80 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf80 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C11orf80 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf80 |
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