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Aliases for C11orf72 Gene

Subcategory (RNA class) for C11orf72 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for C11orf72 Gene

  • Chromosome 11 Open Reading Frame 72 2 3 5

External Ids for C11orf72 Gene

Previous GeneCards Identifiers for C11orf72 Gene

  • GC11M067127
  • GC11M067372

Summaries for C11orf72 Gene

GeneCards Summary for C11orf72 Gene

C11orf72 (Chromosome 11 Open Reading Frame 72) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf72 Gene

Genomics for C11orf72 Gene

Regulatory Elements for C11orf72 Gene

Enhancers for C11orf72 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G067579 1.7 Ensembl ENCODE dbSUPER 12.6 +22.4 22370 10.2 CREB3L1 MLX ZFP64 DMAP1 YBX1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 ENSG00000255119 NUDT8 PTPRCAP NDUFV1 RBM4B C11orf72 DOC2GP ALDH3B2 CDK2AP2 ACY3
GH11G067572 1.5 Ensembl ENCODE dbSUPER 12 +33.7 33697 1.4 HDGF PKNOX1 ATF1 FOXA2 CREB3L1 ARNT ARID4B ZNF2 TCF12 ZNF143 NDUFV1 C11orf72 ENSG00000255119 DOC2GP NUDT8 TBX10 AIP ACY3 ENSG00000227834 ALDH3B2
GH11G067560 1.5 Ensembl ENCODE dbSUPER 11.7 +43.8 43822 3.9 PKNOX1 ATF1 YY1 ZNF766 GATA2 ZNF207 FOS KLF13 DEK CAVIN1 PTPRCAP AIP NDUFV1 CLCF1 CABP2 C11orf72 ENSG00000255119 DOC2GP NUDT8 TBX10
GH11G067604 1.4 ENCODE dbSUPER 0.7 +0.1 89 3.6 CREB3L1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC SSRP1 GLIS1 NBN ENSG00000255119 NUDT8 NDUFV1 CDK2AP2 C11orf72
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf72 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf72 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000041133 -294 1201 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF207

Genomic Location for C11orf72 Gene

Chromosome:
11
Start:
67,602,880 bp from pter
End:
67,606,706 bp from pter
Size:
3,827 bases
Orientation:
Minus strand

Genomic View for C11orf72 Gene

Genes around C11orf72 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf72 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf72 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf72 Gene

Proteins for C11orf72 Gene

  • Protein details for C11orf72 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NBR9-CK072_HUMAN
    Recommended name:
    Uncharacterized protein C11orf72
    Protein Accession:
    Q8NBR9

    Protein attributes for C11orf72 Gene

    Size:
    251 amino acids
    Molecular mass:
    27887 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf72 Gene

Post-translational modifications for C11orf72 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C11orf72 Gene

Domains & Families for C11orf72 Gene

Protein Domains for C11orf72 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf72: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf72 Gene

Function for C11orf72 Gene

Phenotypes for C11orf72 Gene

genes like me logo Genes that share phenotypes with C11orf72: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf72 Gene

Localization for C11orf72 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf72 gene
Compartment Confidence
peroxisome 2
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf72 Gene

Pathways & Interactions for C11orf72 Gene

SuperPathways for C11orf72 Gene

No Data Available

Interacting Proteins for C11orf72 Gene

Gene Ontology (GO) - Biological Process for C11orf72 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf72 Gene

Drugs & Compounds for C11orf72 Gene

No Compound Related Data Available

Transcripts for C11orf72 Gene

mRNA/cDNA for C11orf72 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf72 Gene

Chromosome 11 open reading frame 72:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf72 Gene

No ASD Table

Relevant External Links for C11orf72 Gene

GeneLoc Exon Structure for
C11orf72
ECgene alternative splicing isoforms for
C11orf72

Expression for C11orf72 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf72 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf72 Gene

This gene is overexpressed in Testis (x5.8).

NURSA nuclear receptor signaling pathways regulating expression of C11orf72 Gene:

C11orf72

SOURCE GeneReport for Unigene cluster for C11orf72 Gene:

Hs.382074
genes like me logo Genes that share expression patterns with C11orf72: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf72 Gene

Orthologs for C11orf72 Gene

Evolution for C11orf72 Gene

ENSEMBL:
Gene Tree for C11orf72 (if available)
TreeFam:
Gene Tree for C11orf72 (if available)

No data available for Orthologs for C11orf72 Gene

Paralogs for C11orf72 Gene

No data available for Paralogs for C11orf72 Gene

Variants for C11orf72 Gene

Sequence variations from dbSNP and Humsavar for C11orf72 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs768050261 Pathogenic 67,608,571(+) TGAGT(C/T)GAGGT upstream-variant-2KB, reference, stop-gained
rs886041927 Pathogenic 67,607,057(+) ATCTG(-/TG)CGTTT intron-variant, upstream-variant-2KB, reference, frameshift-variant
rs201727685 Likely pathogenic 67,608,562(+) AAGGT(C/T)CCCTG upstream-variant-2KB, reference, missense
rs863224116 Likely pathogenic 67,608,439(+) TGAAG(A/G)CCGGA upstream-variant-2KB, reference, missense
rs73490568 Likely benign 67,606,939(+) CTATC(A/G)CGCCA upstream-variant-2KB, utr-variant-5-prime

Variation tolerance for C11orf72 Gene

Gene Damage Index Score: 5.31; 70.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf72 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf72

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C11orf72 Gene

Disorders for C11orf72 Gene

Relevant External Links for C11orf72

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf72

No disorders were found for C11orf72 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf72 Gene

Publications for C11orf72 Gene

  1. [Experimental analysis of human specific protein coding open reading frame c11orf72]. (PMID: 23964515) Baskaev K.K. … Buzdin A.A. (Bioorg. Khim. 2013) 2 3 64
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J. … Elledge S.J. (Cell 2009) 3 64

Products for C11orf72 Gene

Sources for C11orf72 Gene

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