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Aliases for C11orf72 Gene

Subcategory (RNA class) for C11orf72 Gene


Quality Score for this RNA gene is


Aliases for C11orf72 Gene

  • Chromosome 11 Open Reading Frame 72 2 3 5

External Ids for C11orf72 Gene

Previous GeneCards Identifiers for C11orf72 Gene

  • GC11M067127
  • GC11M067372

Summaries for C11orf72 Gene

GeneCards Summary for C11orf72 Gene

C11orf72 (Chromosome 11 Open Reading Frame 72) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf72 Gene

Genomics for C11orf72 Gene

Regulatory Elements for C11orf72 Gene

Enhancers for C11orf72 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F067579 1.4 Ensembl ENCODE 12.6 +22.5 22478 10.5 MLX CREB3L1 ZFP64 DMAP1 FEZF1 YBX1 YY1 SLC30A9 ZNF143 ZNF263 ENSG00000255119 NUDT8 PTPRCAP RBM4B NDUFV1 ENSG00000258297 C11orf72 DOC2GP TBX10 ENSG00000255318
GH11F067572 1.2 Ensembl ENCODE 12 +33.7 33697 1.4 ATF1 ARID4B ZNF2 ZNF143 FOS SP5 REST KAT8 ZNF585B SMARCA4 NDUFV1 RBM4B C11orf72 ENSG00000255119 DOC2GP NUDT8 TBX10 AIP ACY3 ENSG00000227834
GH11F067560 1.2 Ensembl ENCODE 11.7 +43.8 43822 3.9 PKNOX1 ATF1 GATA2 FOS JUNB REST TBX21 ZNF592 CREB3 MEF2D PTPRCAP AIP NDUFV1 ENSG00000258297 CLCF1 RBM4B CABP2 C11orf72 ENSG00000255119 DOC2GP
GH11F067604 1.2 ENCODE 0.8 +0.1 89 3.6 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 ENSG00000255119 NUDT8 LRP5 CLCF1 TBC1D10C RHOD NDUFV1 CDK2AP2 C11orf72
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf72 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf72 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000110130 -494 2000 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143

Genomic Location for C11orf72 Gene

67,602,880 bp from pter
67,606,706 bp from pter
3,827 bases
Minus strand

Genomic View for C11orf72 Gene

Genes around C11orf72 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf72 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf72 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf72 Gene

Proteins for C11orf72 Gene

  • Protein details for C11orf72 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf72
    Protein Accession:

    Protein attributes for C11orf72 Gene

    251 amino acids
    Molecular mass:
    27887 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf72 Gene

Post-translational modifications for C11orf72 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C11orf72 Gene

Domains & Families for C11orf72 Gene

Protein Domains for C11orf72 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf72: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf72 Gene

Function for C11orf72 Gene

Phenotypes for C11orf72 Gene

genes like me logo Genes that share phenotypes with C11orf72: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf72 Gene

Localization for C11orf72 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf72 gene
Compartment Confidence
peroxisome 2
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf72 Gene

Pathways & Interactions for C11orf72 Gene

SuperPathways for C11orf72 Gene

No Data Available

Interacting Proteins for C11orf72 Gene

Gene Ontology (GO) - Biological Process for C11orf72 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf72 Gene

Transcripts for C11orf72 Gene

mRNA/cDNA for C11orf72 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf72 Gene

Chromosome 11 open reading frame 72:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf72 Gene

No ASD Table

Relevant External Links for C11orf72 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf72 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C11orf72 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf72 Gene

This gene is overexpressed in Testis (x5.8).

NURSA nuclear receptor signaling pathways regulating expression of C11orf72 Gene:


SOURCE GeneReport for Unigene cluster for C11orf72 Gene:

genes like me logo Genes that share expression patterns with C11orf72: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C11orf72 Gene

Orthologs for C11orf72 Gene

Evolution for C11orf72 Gene

Gene Tree for C11orf72 (if available)
Gene Tree for C11orf72 (if available)

No data available for Orthologs for C11orf72 Gene

Paralogs for C11orf72 Gene

No data available for Paralogs for C11orf72 Gene

Variants for C11orf72 Gene

Sequence variations from dbSNP and Humsavar for C11orf72 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs768050261 Pathogenic 67,608,571(+) TGAGT(C/T)GAGGT upstream-variant-2KB, reference, stop-gained
rs863224116 Likely pathogenic 67,608,439(+) TGAAG(A/G)CCGGA upstream-variant-2KB, reference, missense
rs780851340 Likely benign 67,608,616(+) GGCCC(A/G)ACTGG upstream-variant-2KB, reference, missense
rs147242476 Uncertain significance 67,608,679(+) TCCCC(A/G)CTGGC upstream-variant-2KB, reference, missense
rs754664225 Uncertain significance 67,608,403(+) AGCAC(C/G)CAAGA upstream-variant-2KB, reference, missense

Variation tolerance for C11orf72 Gene

Gene Damage Index Score: 5.31; 70.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf72 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C11orf72 Gene

Disorders for C11orf72 Gene

Relevant External Links for C11orf72

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C11orf72 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf72 Gene

Publications for C11orf72 Gene

  1. [Experimental analysis of human specific protein coding open reading frame c11orf72]. (PMID: 23964515) Baskaev K.K. … Buzdin A.A. (Bioorg. Khim. 2013) 2 3 64
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J. … Elledge S.J. (Cell 2009) 3 64

Products for C11orf72 Gene

Sources for C11orf72 Gene

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