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Aliases for C11orf71 Gene

Aliases for C11orf71 Gene

  • Chromosome 11 Open Reading Frame 71 2 3 5
  • Uncharacterized Protein C11orf71 3
  • Up-Regulated In Lung Cancer 7 3
  • URLC7 3

External Ids for C11orf71 Gene

Previous GeneCards Identifiers for C11orf71 Gene

  • GC11M113767
  • GC11M114262
  • GC11M110190

Summaries for C11orf71 Gene

GeneCards Summary for C11orf71 Gene

C11orf71 (Chromosome 11 Open Reading Frame 71) is a Protein Coding gene.

Additional gene information for C11orf71 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf71 Gene

Genomics for C11orf71 Gene

Regulatory Elements for C11orf71 Gene

Enhancers for C11orf71 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H114288 1.5 Ensembl ENCODE dbSUPER 10.5 +105.1 105096 13 FOXA2 PKNOX1 ATF1 SIN3A BRCA1 YY1 TCF12 GATA2 ATF7 FOS NNMT ZW10 LOC101928940 RBM7 C11orf71 ENSG00000255663 TTC12 GC11P114306 GC11M114263
GH11H114353 1.1 FANTOM5 ENCODE 11.2 +46.4 46408 0 PKNOX1 ZNF362 ATF1 NFIB JUN CEBPB MNT ZNF518A ATF2 JUND LOC101928940 ENSG00000270179 ENSG00000255663 C11orf71 RBM7 ENSG00000256947 GC11P114340
GH11H114348 0.9 Ensembl ENCODE 11.2 +51.7 51735 1 SMARCE1 CTCF ZNF654 FOS PRDM10 REST RAD21 TCF7L2 REXO2 LOC101928940 RBM7 ENSG00000255663 C11orf71 ENSG00000256947 GC11P114340
GH11H114365 0.7 Ensembl ENCODE 11.1 +33.7 33700 2 JUND POLR2A JUN RBM7 C11orf71 ENSG00000255663 ENSG00000270179 LOC101928940 ENSG00000256947
GH11H114447 0.7 ENCODE 10.9 -47.6 -47553 1 GTF2E2 ZNF175 CEBPG ZNF644 TRIM24 ZNF584 NR4A1 CEBPB EP300 HDAC8 RBM7 ENSG00000255663 C11orf71 LOC101928940 LOC100422382 REXO2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf71 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf71 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000045256 -250 2801 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766 CBX5

Genomic Location for C11orf71 Gene

Chromosome:
11
Start:
114,391,443 bp from pter
End:
114,400,550 bp from pter
Size:
9,108 bases
Orientation:
Minus strand

Genomic View for C11orf71 Gene

Genes around C11orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf71 Gene

Proteins for C11orf71 Gene

  • Protein details for C11orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IPW1-CK071_HUMAN
    Recommended name:
    Uncharacterized protein C11orf71
    Protein Accession:
    Q6IPW1
    Secondary Accessions:
    • Q6IAD3
    • Q9NXX1

    Protein attributes for C11orf71 Gene

    Size:
    123 amino acids
    Molecular mass:
    13249 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf71 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C11orf71 Gene

Post-translational modifications for C11orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf71 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf71 Gene

Domains & Families for C11orf71 Gene

Gene Families for C11orf71 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf71 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf71: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf71 Gene

Function for C11orf71 Gene

Phenotypes From GWAS Catalog for C11orf71 Gene

genes like me logo Genes that share phenotypes with C11orf71: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf71
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf71 Gene

Localization for C11orf71 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf71 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Nucleoplasm (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf71 Gene

Pathways & Interactions for C11orf71 Gene

SuperPathways for C11orf71 Gene

No Data Available

Interacting Proteins for C11orf71 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000325508%0d%0a9606.ENSP00000221498%0d%0a
Selected Interacting proteins: ENSP00000325508 Q6IPW1-CK071_HUMAN for C11orf71 Gene via STRING IID

Gene Ontology (GO) - Biological Process for C11orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf71 Gene

Drugs & Compounds for C11orf71 Gene

No Compound Related Data Available

Transcripts for C11orf71 Gene

mRNA/cDNA for C11orf71 Gene

Unigene Clusters for C11orf71 Gene

Chromosome 11 open reading frame 71:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf71
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf71 Gene

No ASD Table

Relevant External Links for C11orf71 Gene

GeneLoc Exon Structure for
C11orf71
ECgene alternative splicing isoforms for
C11orf71

Expression for C11orf71 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf71 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C11orf71 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf71 Gene



Protein tissue co-expression partners for C11orf71 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf71 Gene:

C11orf71

SOURCE GeneReport for Unigene cluster for C11orf71 Gene:

Hs.715083
genes like me logo Genes that share expression patterns with C11orf71: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf71 Gene

Orthologs for C11orf71 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf71 33
  • 99.09 (n)
C11orf71 34
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C15H11orf71 33 34
  • 79.24 (n)
rat
(Rattus norvegicus)
Mammalia RGD1563941 33
  • 75.52 (n)
mouse
(Mus musculus)
Mammalia Gm5617 33 16 34
  • 75.22 (n)
dog
(Canis familiaris)
Mammalia C11orf71 34
  • 59 (a)
OneToOne
Species where no ortholog for C11orf71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf71 Gene

ENSEMBL:
Gene Tree for C11orf71 (if available)
TreeFam:
Gene Tree for C11orf71 (if available)

Paralogs for C11orf71 Gene

No data available for Paralogs for C11orf71 Gene

Variants for C11orf71 Gene

Sequence variations from dbSNP and Humsavar for C11orf71 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000122162 -- 114,400,453(+) TAACT(A/G)AGCCT upstream-variant-2KB, utr-variant-5-prime
rs1000142686 -- 114,399,283(+) ACAGT(A/G)AGTAG intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs1000369583 -- 114,392,892(+) CACCA(C/T)TACAT intron-variant
rs1000794307 -- 114,401,256(+) TTAGT(A/G)TTGCT intron-variant, upstream-variant-2KB
rs1001064391 -- 114,393,629(+) GAGCA(C/T)TCGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf71 Gene

Variant ID Type Subtype PubMed ID
esv3548365 CNV deletion 23714750

Variation tolerance for C11orf71 Gene

Residual Variation Intolerance Score: 75.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.38; 27.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf71 Gene

Disorders for C11orf71 Gene

Relevant External Links for C11orf71

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf71

No disorders were found for C11orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf71 Gene

Publications for C11orf71 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 60
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J … Yang X (Molecular systems biology 2011) 3 60

Products for C11orf71 Gene

Sources for C11orf71 Gene

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