Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C11orf70 Gene

Aliases for C11orf70 Gene

  • Chromosome 11 Open Reading Frame 70 2 3

External Ids for C11orf70 Gene

Previous GeneCards Identifiers for C11orf70 Gene

  • GC11P101424
  • GC11P101918
  • GC11P097844

Summaries for C11orf70 Gene

GeneCards Summary for C11orf70 Gene

C11orf70 (Chromosome 11 Open Reading Frame 70) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf70 Gene

Genomics for C11orf70 Gene

Regulatory Elements for C11orf70 Gene

Transcription factor binding sites by QIAGEN in the C11orf70 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C11orf70 Gene

102,047,411 bp from pter
102,084,560 bp from pter
37,150 bases
Plus strand

Genomic View for C11orf70 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C11orf70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf70 Gene

Proteins for C11orf70 Gene

  • Protein details for C11orf70 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf70
    Protein Accession:
    Secondary Accessions:
    • E9PJU1

    Protein attributes for C11orf70 Gene

    267 amino acids
    Molecular mass:
    30859 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf70 Gene


neXtProt entry for C11orf70 Gene

Proteomics data for C11orf70 Gene at MOPED

Post-translational modifications for C11orf70 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf70 Gene

No data available for DME Specific Peptides for C11orf70 Gene

Domains & Families for C11orf70 Gene

Protein Domains for C11orf70 Gene


Suggested Antigen Peptide Sequences for C11orf70 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf70: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C11orf70 Gene

Function for C11orf70 Gene

Phenotypes for C11orf70 Gene

GenomeRNAi human phenotypes for C11orf70:
genes like me logo Genes that share phenotypes with C11orf70: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf70

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf70 Gene

Localization for C11orf70 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C11orf70 Gene

Pathways & Interactions for C11orf70 Gene

SuperPathways for C11orf70 Gene

No Data Available

Interacting Proteins for C11orf70 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000414390 for C11orf70 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for C11orf70 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf70 Gene

Drugs & Compounds for C11orf70 Gene

No Compound Related Data Available

Transcripts for C11orf70 Gene

Unigene Clusters for C11orf70 Gene

Chromosome 11 open reading frame 70:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf70

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf70 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7
SP1: -
SP2: - - -

Relevant External Links for C11orf70 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf70 Gene

mRNA expression in normal human tissues for C11orf70 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf70 Gene

This gene is overexpressed in Testis (x11.0).

Protein differential expression in normal tissues from HIPED for C11orf70 Gene

This gene is overexpressed in Testis (30.7), NK cells (22.3), and Ovary (14.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for C11orf70 Gene

SOURCE GeneReport for Unigene cluster for C11orf70 Gene Hs.98328

genes like me logo Genes that share expression patterns with C11orf70: view

Protein tissue co-expression partners for C11orf70 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C11orf70 Gene

Orthologs for C11orf70 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf70 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C15H11orf70 35
  • 90.14 (n)
  • 87.27 (a)
-- 36
  • 88 (a)
-- 36
  • 75 (a)
(Canis familiaris)
Mammalia C5H11orf70 35
  • 90.48 (n)
  • 89.16 (a)
C11orf70 36
  • 89 (a)
(Mus musculus)
Mammalia 9230110C19Rik 35
  • 83.52 (n)
  • 83.52 (a)
9230110C19Rik 16
9230110C19Rik 36
  • 84 (a)
(Pan troglodytes)
Mammalia C11H11orf70 35
  • 99.38 (n)
  • 99.63 (a)
C11ORF70 36
  • 100 (a)
(Rattus norvegicus)
Mammalia LOC654482 35
  • 82.27 (n)
  • 82.77 (a)
(Monodelphis domestica)
Mammalia C11orf70 36
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia C11orf70 36
  • 76 (a)
(Gallus gallus)
Aves C1H11ORF70 35
  • 67.68 (n)
  • 64.26 (a)
C1H11ORF70 36
  • 64 (a)
(Anolis carolinensis)
Reptilia C11orf70 36
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c11orf70 35
  • 66.14 (n)
  • 62.55 (a)
Str.17259 35
(Danio rerio)
Actinopterygii si:rp71-1p14.7 35
  • 58.02 (n)
  • 51.15 (a)
C21H11orf70 36
  • 49 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
Species with no ortholog for C11orf70:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf70 Gene

Gene Tree for C11orf70 (if available)
Gene Tree for C11orf70 (if available)

Paralogs for C11orf70 Gene

No data available for Paralogs for C11orf70 Gene

Variants for C11orf70 Gene

Sequence variations from dbSNP and Humsavar for C11orf70 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs948734 -- 102,058,178(+) CCACC(C/T)CCGGA intron-variant
rs2156168 -- 102,057,248(+) acagg(A/G)aaatc intron-variant
rs4366456 -- 102,050,398(+) CACTA(C/G)TGAAC intron-variant
rs6590945 -- 102,083,569(+) AACAT(G/T)TCTAC utr-variant-3-prime
rs6590946 -- 102,083,728(+) AGTAA(C/T)GTTCT utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C11orf70 Gene

Variant ID Type Subtype PubMed ID
nsv898333 CNV Gain 21882294

Variation tolerance for C11orf70 Gene

Residual Variation Intolerance Score: 23.79% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.76; 16.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf70 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf70 Gene

Disorders for C11orf70 Gene

Relevant External Links for C11orf70

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C11orf70: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf70 Gene

Publications for C11orf70 Gene

  1. Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. (PMID: 25192599) Wang T. … Xu J. (Neurobiol. Aging 2015) 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 67
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for C11orf70 Gene

Sources for C11orf70 Gene

Back to Top