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Aliases for C11orf65 Gene

Aliases for C11orf65 Gene

  • Chromosome 11 Open Reading Frame 65 2 3

External Ids for C11orf65 Gene

Summaries for C11orf65 Gene

GeneCards Summary for C11orf65 Gene

C11orf65 (Chromosome 11 Open Reading Frame 65) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf65 Gene

Genomics for C11orf65 Gene

Genomic Location for C11orf65 Gene

Start:
108,308,519 bp from pter
End:
108,467,531 bp from pter
Size:
159,013 bases
Orientation:
Minus strand

Genomic View for C11orf65 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C11orf65 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf65 Gene

Regulatory Elements for C11orf65 Gene

Proteins for C11orf65 Gene

  • Protein details for C11orf65 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCR3-CK065_HUMAN
    Recommended name:
    Uncharacterized protein C11orf65
    Protein Accession:
    Q8NCR3
    Secondary Accessions:
    • B4DZU4
    • Q6PCA8

    Protein attributes for C11orf65 Gene

    Size:
    313 amino acids
    Molecular mass:
    36720 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf65 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C11orf65 Gene

Proteomics data for C11orf65 Gene at MOPED

Post-translational modifications for C11orf65 Gene

No Post-translational modifications

Other Protein References for C11orf65 Gene

No data available for DME Specific Peptides for C11orf65 Gene

Domains for C11orf65 Gene

Protein Domains for C11orf65 Gene

ProtoNet:
genes like me logo Genes that share domains with C11orf65: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C11orf65 Gene

Function for C11orf65 Gene

Gene Ontology (GO) - Molecular Function for C11orf65 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C11orf65: view

miRNA for C11orf65 Gene

miRTarBase miRNAs that target C11orf65

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for C11orf65 Gene

Localization for C11orf65 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C11orf65 Gene COMPARTMENTS Subcellular localization image for C11orf65 gene
Compartment Confidence
cytosol 3
nucleus 2

No data available for Gene Ontology (GO) - Cellular Components for C11orf65 Gene

Pathways for C11orf65 Gene

SuperPathways for C11orf65 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C11orf65 Gene

None

No data available for Pathways by source for C11orf65 Gene

Compounds for C11orf65 Gene

(1) PharmGKB related drug/compound annotations for C11orf65 Gene

Drug/compound Annotation
metformin CA
genes like me logo Genes that share compounds with C11orf65: view

Transcripts for C11orf65 Gene

mRNA/cDNA for C11orf65 Gene

(10) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf65 Gene

Chromosome 11 open reading frame 65:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf65 Gene

No ASD Table

Relevant External Links for C11orf65 Gene

GeneLoc Exon Structure for
C11orf65
ECgene alternative splicing isoforms for
C11orf65

Expression for C11orf65 Gene

mRNA expression in normal human tissues for C11orf65 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C11orf65 Gene

This gene is overexpressed in Testis (22.8).

SOURCE GeneReport for Unigene cluster for C11orf65 Gene Hs.653180

genes like me logo Genes that share expressions with C11orf65: view

Orthologs for C11orf65 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf65 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf65 36
  • 99.57 (n)
  • 100 (a)
C11orf65 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C15H11orf65 36
  • 85.04 (n)
  • 75 (a)
dog
(Canis familiaris)
Mammalia C11orf65 37
  • 81 (a)
OneToOne
C5H11orf65 36
  • 86.11 (n)
  • 77.24 (a)
mouse
(Mus musculus)
Mammalia 4930550C14Rik 36
  • 78.22 (n)
  • 71.95 (a)
4930550C14Rik 16
4930550C14Rik 37
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C11orf65 37
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C11orf65 37
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1311251 36
  • 77 (n)
  • 71.67 (a)
lizard
(Anolis carolinensis)
Reptilia C11orf65 37
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490935 36
  • 59.25 (n)
  • 51.7 (a)
zebrafish
(Danio rerio)
Actinopterygii C24H11orf65 37
  • 37 (a)
OneToOne
gb:co360592 36
  • 57.12 (n)
  • 45.64 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13913 36
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3681 37
  • 51 (a)
OneToOne
Species with no ortholog for C11orf65:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf65 Gene

ENSEMBL:
Gene Tree for C11orf65 (if available)
TreeFam:
Gene Tree for C11orf65 (if available)

Paralogs for C11orf65 Gene

Pseudogenes.org Pseudogenes for C11orf65 Gene

genes like me logo Genes that share paralogs with C11orf65: view

No data available for Paralogs for C11orf65 Gene

Variants for C11orf65 Gene

Sequence variations from dbSNP and Humsavar for C11orf65 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs113995 -- 108,386,110(+) TCTCA(A/T)GACTT intron-variant
rs170546 -- 108,376,067(-) tctgt(C/G)taatg intron-variant
rs170547 -- 108,373,888(-) cctcc(A/G)agcca intron-variant
rs172894 -- 108,391,363(+) tgtgg(A/C)tccac intron-variant
rs172895 -- 108,395,149(+) aaaat(C/G)ataac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf65 Gene

Variant ID Type Subtype PubMed ID
nsv832262 CNV Loss 17160897
nsv832263 CNV Gain 17160897
esv21753 CNV Gain 19812545
esv1612880 CNV Insertion 17803354

Relevant External Links for C11orf65 Gene

HapMap Linkage Disequilibrium report
C11orf65
Human Gene Mutation Database (HGMD)
C11orf65

Disorders for C11orf65 Gene

Relevant External Links for C11orf65

Genetic Association Database (GAD)
C11orf65
Human Genome Epidemiology (HuGE) Navigator
C11orf65
genes like me logo Genes that share disorders with C11orf65: view

No data available for UniProtKB/Swiss-Prot for C11orf65 Gene

Publications for C11orf65 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Does metformin work for everyone? A genome-wide association study for metformin response. (PMID: 21845381) Florez J.C. (Curr. Diab. Rep. 2011) 3 49
  4. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 49
  5. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. (PMID: 21186350) . … Pearson E.R. (Nat. Genet. 2011) 3

Products for C11orf65 Gene

Sources for C11orf65 Gene

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