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Aliases for C11orf58 Gene

Aliases for C11orf58 Gene

  • Chromosome 11 Open Reading Frame 58 2 3 5
  • SMAP 3 4
  • Small Acidic Protein 2
  • IMAGE145052 3

External Ids for C11orf58 Gene

Previous GeneCards Identifiers for C11orf58 Gene

  • GC11P016717
  • GC11P016444

Summaries for C11orf58 Gene

GeneCards Summary for C11orf58 Gene

C11orf58 (Chromosome 11 Open Reading Frame 58) is a Protein Coding gene.

Gene Wiki entry for C11orf58 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf58 Gene

Genomics for C11orf58 Gene

Regulatory Elements for C11orf58 Gene

Promoters for C11orf58 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C11orf58 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf58 Gene

Chromosome:
11
Start:
16,613,132 bp from pter
End:
16,758,354 bp from pter
Size:
145,223 bases
Orientation:
Plus strand

Genomic View for C11orf58 Gene

Genes around C11orf58 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf58 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf58 Gene

Proteins for C11orf58 Gene

  • Protein details for C11orf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O00193-SMAP_HUMAN
    Recommended name:
    Small acidic protein
    Protein Accession:
    O00193
    Secondary Accessions:
    • B2RD28

    Protein attributes for C11orf58 Gene

    Size:
    183 amino acids
    Molecular mass:
    20333 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf58 Gene

Proteomics data for C11orf58 Gene at MOPED

Post-translational modifications for C11orf58 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf58 Gene

No data available for DME Specific Peptides for C11orf58 Gene

Domains & Families for C11orf58 Gene

Protein Domains for C11orf58 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

O00193

UniProtKB/Swiss-Prot:

SMAP_HUMAN :
  • Belongs to the SMAP family.
Family:
  • Belongs to the SMAP family.
genes like me logo Genes that share domains with C11orf58: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for C11orf58 Gene

Function for C11orf58 Gene

Phenotypes for C11orf58 Gene

genes like me logo Genes that share phenotypes with C11orf58: view

Animal Model Products

  • Taconic Biosciences Mouse Models for C11orf58

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf58 Gene

Localization for C11orf58 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C11orf58 Gene COMPARTMENTS Subcellular localization image for C11orf58 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf58 Gene

Pathways & Interactions for C11orf58 Gene

SuperPathways for C11orf58 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C11orf58 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf58 Gene

Drugs & Compounds for C11orf58 Gene

(1) Drugs for C11orf58 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with C11orf58: view

Transcripts for C11orf58 Gene

Unigene Clusters for C11orf58 Gene

Chromosome 11 open reading frame 58:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf58 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d · 8e
SP1: - - - -
SP2: - - - - -
SP3: - - - -
SP4: - - - - - -
SP5: - - - - - -
SP6: - -
SP7: - - - - - -
SP8: - -
SP9: - - -

Relevant External Links for C11orf58 Gene

GeneLoc Exon Structure for
C11orf58
ECgene alternative splicing isoforms for
C11orf58

Expression for C11orf58 Gene

mRNA expression in normal human tissues for C11orf58 Gene

Protein differential expression in normal tissues from HIPED for C11orf58 Gene

This gene is overexpressed in Adrenal (47.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C11orf58 Gene



SOURCE GeneReport for Unigene cluster for C11orf58 Gene Hs.645792

genes like me logo Genes that share expression patterns with C11orf58: view

Protein tissue co-expression partners for C11orf58 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C11orf58 Gene

Orthologs for C11orf58 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf58 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C15H11orf58 35
  • 93 (n)
  • 94.48 (a)
SMAP 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C21H11orf58 35
  • 93.77 (n)
  • 95.6 (a)
-- 36
  • 90 (a)
OneToMany
-- 36
  • 99 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 1110004F10Rik 35
  • 85.27 (n)
  • 92.27 (a)
1110004F10Rik 16
1110004F10Rik 36
  • 96 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf58 35
  • 100 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia RGD1311703 35
  • 85.27 (n)
  • 91.16 (a)
oppossum
(Monodelphis domestica)
Mammalia C11orf58 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C11orf58 36
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H11ORF58 35
  • 77 (n)
  • 75.44 (a)
C5H11ORF58 36
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C11orf58 36
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c11orf58 35
  • 58.38 (n)
  • 55.8 (a)
Str.5966 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.18476 35
zebrafish
(Danio rerio)
Actinopterygii zgc56106 35
zgc:56106 35
  • 71.09 (n)
  • 75.51 (a)
C18H11orf58 36
  • 55 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5834 35
Species with no ortholog for C11orf58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf58 Gene

ENSEMBL:
Gene Tree for C11orf58 (if available)
TreeFam:
Gene Tree for C11orf58 (if available)

Paralogs for C11orf58 Gene

(2) SIMAP similar genes for C11orf58 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for C11orf58 Gene

genes like me logo Genes that share paralogs with C11orf58: view

No data available for Paralogs for C11orf58 Gene

Variants for C11orf58 Gene

Sequence variations from dbSNP and Humsavar for C11orf58 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs6677 -- 16,755,585(+) TAGTT(G/T)CCTGT utr-variant-3-prime
rs1044315 -- 16,757,719(+) AAATG(C/T)ACTTT utr-variant-3-prime
rs1139197 -- 16,740,460(+) gtggc(A/G)cgatc intron-variant
rs1139198 -- 16,740,482(+) cctgc(A/G)gcctc intron-variant
rs1139200 -- 16,740,489(+) cctcc(A/G)cctcc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf58 Gene

Variant ID Type Subtype PubMed ID
esv23566 CNV Loss 19812545
esv2571561 CNV Deletion 19546169

Variation tolerance for C11orf58 Gene

Residual Variation Intolerance Score: 43.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.21; 4.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf58 Gene

HapMap Linkage Disequilibrium report
C11orf58

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf58 Gene

Disorders for C11orf58 Gene

Relevant External Links for C11orf58

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf58

No disorders were found for C11orf58 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf58 Gene

Publications for C11orf58 Gene

  1. Novel genes expressed in the chick otocyst during development: identification using differential display of RNA. (PMID: 9263035) Gong T.-W. … Lomax M.I. (Int. J. Dev. Neurosci. 1997) 2 3 4 23 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. A high-throughput approach for measuring temporal changes in the interactome. (PMID: 22863883) Kristensen A.R. … Foster L.J. (Nat. Methods 2012) 3
  4. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 3
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3

Products for C11orf58 Gene

Sources for C11orf58 Gene

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