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Aliases for C11orf57 Gene

Aliases for C11orf57 Gene

  • Chromosome 11 Open Reading Frame 57 2 3

External Ids for C11orf57 Gene

Previous GeneCards Identifiers for C11orf57 Gene

  • GC11P111451
  • GC11P111944
  • GC11P107868

Summaries for C11orf57 Gene

GeneCards Summary for C11orf57 Gene

C11orf57 (Chromosome 11 Open Reading Frame 57) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf57 Gene

Genomics for C11orf57 Gene

Regulatory Elements for C11orf57 Gene

Genomic Location for C11orf57 Gene

112,074,086 bp from pter
112,085,150 bp from pter
11,065 bases
Plus strand

Genomic View for C11orf57 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C11orf57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf57 Gene

Proteins for C11orf57 Gene

  • Protein details for C11orf57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf57
    Protein Accession:
    Secondary Accessions:
    • Q5RL41
    • Q6IN53
    • Q7Z357
    • Q8N2T3

    Protein attributes for C11orf57 Gene

    292 amino acids
    Molecular mass:
    34110 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf57 Gene


neXtProt entry for C11orf57 Gene

Proteomics data for C11orf57 Gene at MOPED

Post-translational modifications for C11orf57 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C11orf57 Gene

Domains & Families for C11orf57 Gene

Protein Domains for C11orf57 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf57: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf57 Gene

Function for C11orf57 Gene

Gene Ontology (GO) - Molecular Function for C11orf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C11orf57: view

Phenotypes for C11orf57 Gene

GenomeRNAi human phenotypes for C11orf57:
genes like me logo Genes that share phenotypes with C11orf57: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf57

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf57 Gene

Localization for C11orf57 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C11orf57 Gene

Pathways & Interactions for C11orf57 Gene

SuperPathways for C11orf57 Gene

No Data Available

Interacting Proteins for C11orf57 Gene

Gene Ontology (GO) - Biological Process for C11orf57 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf57 Gene

Drugs & Compounds for C11orf57 Gene

No Compound Related Data Available

Transcripts for C11orf57 Gene

Unigene Clusters for C11orf57 Gene

Chromosome 11 open reading frame 57:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C11orf57

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf57 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b
SP1: - - - -
SP2: - -
SP3: - - - -
SP4: - - -
SP5: -
SP6: - - -
SP7: - -

Relevant External Links for C11orf57 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf57 Gene

mRNA expression in normal human tissues for C11orf57 Gene

Protein differential expression in normal tissues from HIPED for C11orf57 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (63.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for C11orf57 Gene

SOURCE GeneReport for Unigene cluster for C11orf57 Gene Hs.195060

genes like me logo Genes that share expression patterns with C11orf57: view

Protein tissue co-expression partners for C11orf57 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C11orf57 Gene

Orthologs for C11orf57 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf57 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C15H11orf57 35
  • 93.41 (n)
  • 92.78 (a)
MGC143285 36
  • 93 (a)
(Canis familiaris)
Mammalia C5H11orf57 35
  • 92.61 (n)
  • 91.81 (a)
C11orf57 36
  • 92 (a)
(Mus musculus)
Mammalia AU019823 35
  • 85.16 (n)
  • 83.9 (a)
AU019823 16
AU019823 36
  • 84 (a)
(Pan troglodytes)
Mammalia C11H11orf57 35
  • 99.54 (n)
  • 99.32 (a)
C11orf57 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC100151767 35
  • 86.03 (n)
  • 83.85 (a)
(Monodelphis domestica)
Mammalia C11orf57 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia C11orf57 36
  • 57 (a)
(Gallus gallus)
Aves C24H11ORF57 35
  • 67.13 (n)
  • 61.38 (a)
C11orf57 36
  • 50 (a)
(Anolis carolinensis)
Reptilia C11orf57 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c11orf57 35
  • 54.69 (n)
  • 45.91 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.1381 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5815 35
(Danio rerio)
Actinopterygii C15H11orf57 36
  • 42 (a)
Species with no ortholog for C11orf57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf57 Gene

Gene Tree for C11orf57 (if available)
Gene Tree for C11orf57 (if available)

Paralogs for C11orf57 Gene

No data available for Paralogs for C11orf57 Gene

Variants for C11orf57 Gene

Sequence variations from dbSNP and Humsavar for C11orf57 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs10255 -- 112,083,292(-) GATTG(G/T)TGTAC utr-variant-3-prime, nc-transcript-variant
rs483788 -- 112,076,833(+) ATGAC(A/G)ATTCT intron-variant
rs560490 -- 112,080,270(-) AAAAA(A/G)GGCAA intron-variant
rs1139692 -- 112,084,240(-) TACTG(G/T)GAAGT utr-variant-3-prime, nc-transcript-variant
rs1139693 -- 112,084,195(-) GAAGG(G/T)GAACT utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf57 Gene

Variant ID Type Subtype PubMed ID
esv2745077 CNV Deletion 23290073

Variation tolerance for C11orf57 Gene

Residual Variation Intolerance Score: 23.95% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.89; 18.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf57 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf57 Gene

Disorders for C11orf57 Gene

Relevant External Links for C11orf57

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C11orf57: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf57 Gene

Publications for C11orf57 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PMID: 23455922) Varjosalo M. … Superti-Furga G. (Nat. Methods 2013) 67
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67

Products for C11orf57 Gene

Sources for C11orf57 Gene

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