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Aliases for C11orf52 Gene

Aliases for C11orf52 Gene

  • Chromosome 11 Open Reading Frame 52 2 3 5

External Ids for C11orf52 Gene

Previous GeneCards Identifiers for C11orf52 Gene

  • GC11P111295
  • GC11P111789
  • GC11P107713

Summaries for C11orf52 Gene

GeneCards Summary for C11orf52 Gene

C11orf52 (Chromosome 11 Open Reading Frame 52) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf52 Gene

Genomics for C11orf52 Gene

Regulatory Elements for C11orf52 Gene

Enhancers for C11orf52 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around C11orf52 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf52 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for C11orf52 Gene

111,918,032 bp from pter
111,926,872 bp from pter
8,841 bases
Plus strand

Genomic View for C11orf52 Gene

Genes around C11orf52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf52 Gene

Proteins for C11orf52 Gene

  • Protein details for C11orf52 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf52
    Protein Accession:

    Protein attributes for C11orf52 Gene

    123 amino acids
    Molecular mass:
    13921 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf52 Gene

Post-translational modifications for C11orf52 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf52 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf52 Gene

Domains & Families for C11orf52 Gene

Protein Domains for C11orf52 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf52: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf52 Gene

Function for C11orf52 Gene

genes like me logo Genes that share phenotypes with C11orf52: view

Animal Model Products

CRISPR Products

miRNA for C11orf52 Gene

miRTarBase miRNAs that target C11orf52

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf52 Gene

Localization for C11orf52 Gene

Subcellular locations from

Jensen Localization Image for C11orf52 Gene COMPARTMENTS Subcellular localization image for C11orf52 gene
Compartment Confidence
extracellular 5
mitochondrion 2
nucleus 2
endoplasmic reticulum 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C11orf52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with C11orf52: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for C11orf52 Gene

Pathways & Interactions for C11orf52 Gene

SuperPathways for C11orf52 Gene

Superpath Contained pathways
1 MAPK signaling pathway
genes like me logo Genes that share pathways with C11orf52: view

Pathways by source for C11orf52 Gene

1 BioSystems pathway for C11orf52 Gene

Interacting Proteins for C11orf52 Gene

Selected Interacting proteins: Q96A22-CK052_HUMAN for C11orf52 Gene via IID

Gene Ontology (GO) - Biological Process for C11orf52 Gene


No data available for SIGNOR curated interactions for C11orf52 Gene

Drugs & Compounds for C11orf52 Gene

No Compound Related Data Available

Transcripts for C11orf52 Gene

mRNA/cDNA for C11orf52 Gene

Unigene Clusters for C11orf52 Gene

Chromosome 11 open reading frame 52:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf52 Gene

No ASD Table

Relevant External Links for C11orf52 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf52 Gene

mRNA expression in normal human tissues for C11orf52 Gene

Protein differential expression in normal tissues from HIPED for C11orf52 Gene

This gene is overexpressed in Urine (39.2), Placenta (13.7), and Lung (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf52 Gene

Protein tissue co-expression partners for C11orf52 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf52 Gene:


SOURCE GeneReport for Unigene cluster for C11orf52 Gene:

genes like me logo Genes that share expression patterns with C11orf52: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C11orf52 Gene

Orthologs for C11orf52 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf52 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C15H11orf52 34
  • 81.84 (n)
  • 68.29 (a)
C11orf52 35
  • 62 (a)
(Canis familiaris)
Mammalia C5H11orf52 34
  • 82.38 (n)
  • 69.92 (a)
C11orf52 35
  • 66 (a)
(Mus musculus)
Mammalia 2310030G06Rik 34
  • 75.88 (n)
  • 64.23 (a)
2310030G06Rik 16
2310030G06Rik 35
  • 57 (a)
(Pan troglodytes)
Mammalia C11H11orf52 34
  • 99.19 (n)
  • 99.19 (a)
C11orf52 35
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC689959 34
  • 72.9 (n)
  • 63.41 (a)
Species where no ortholog for C11orf52 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf52 Gene

Gene Tree for C11orf52 (if available)
Gene Tree for C11orf52 (if available)

Paralogs for C11orf52 Gene

No data available for Paralogs for C11orf52 Gene

Variants for C11orf52 Gene

Sequence variations from dbSNP and Humsavar for C11orf52 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
VAR_029587 -

Variation tolerance for C11orf52 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.90; 74.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf52 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C11orf52 Gene

Disorders for C11orf52 Gene

Relevant External Links for C11orf52

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C11orf52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf52 Gene

Publications for C11orf52 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 65
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3 65
  5. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. (PMID: 23533145) Principe S. … Drake R.R. (Proteomics 2013) 3 65

Products for C11orf52 Gene

Sources for C11orf52 Gene

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