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Aliases for C11orf42 Gene

Aliases for C11orf42 Gene

  • Chromosome 11 Open Reading Frame 42 2 3 5

External Ids for C11orf42 Gene

Previous GeneCards Identifiers for C11orf42 Gene

  • GC11P006187
  • GC11P005888

Summaries for C11orf42 Gene

GeneCards Summary for C11orf42 Gene

C11orf42 (Chromosome 11 Open Reading Frame 42) is a Protein Coding gene.

Additional gene information for C11orf42 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf42 Gene

Genomics for C11orf42 Gene

Regulatory Elements for C11orf42 Gene

Enhancers for C11orf42 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H006249 1.1 Ensembl ENCODE 10.9 +45.1 45083 1 TBP BRCA1 TCF12 ZNF766 GATA2 ELK1 RCOR1 FOS ZBTB11 USF2 C11orf42 OR52W1 CAVIN3 OR56A1 GC11M006236 CCKBR
GH11H006250 1 Ensembl ENCODE 10.5 +47.3 47297 2 CTCF FOXA2 TAL1 ZNF175 RAD21 TCF12 POLR2A NCOR1 EGR1 SMC3 FAM160A2 CCKBR C11orf42 OR52W1 OR56A1 GC11M006236
GH11H007019 0.9 ENCODE 10.4 +815.3 815266 2 PKNOX1 ZNF473 ZFP64 INSM2 ARID4B SIN3A YY1 ETS1 MIXL1 SP3 DNHD1 ENSG00000254641 C11orf42 CYB5R2 ZNF214 ARFIP2 PIR41527
GH11H006287 0.6 ENCODE 10 +83.6 83608 2 RFX1 CEBPB CEBPG DPF2 JUND GATA3 SKIL CTBP1 FOS CAVIN3 CCKBR FAM160A2 C11orf42 OR52W1 OR52B2 OR56A1 ENSG00000270435 GC11M006277
GH11H006281 0.6 ENCODE 9.5 +76.7 76708 0 CTCF RNF2 SOX6 SMC3 ZNF384 ZNF2 RAD21 FOXA1 CCKBR CAVIN3 OR52B2 OR56A1 FAM160A2 C11orf42 OR52W1 GC11M006277 ENSG00000270435
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf42 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf42 Gene

6,205,043 bp from pter
6,231,450 bp from pter
26,408 bases
Plus strand

Genomic View for C11orf42 Gene

Genes around C11orf42 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf42 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf42 Gene

Proteins for C11orf42 Gene

  • Protein details for C11orf42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C11orf42
    Protein Accession:

    Protein attributes for C11orf42 Gene

    333 amino acids
    Molecular mass:
    36368 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf42 Gene

Post-translational modifications for C11orf42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf42 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf42 Gene

Domains & Families for C11orf42 Gene

Gene Families for C11orf42 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C11orf42 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf42: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf42 Gene

Function for C11orf42 Gene

genes like me logo Genes that share phenotypes with C11orf42: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf42
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C11orf42 Gene

Localization for C11orf42 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf42 gene
Compartment Confidence
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C11orf42 Gene

Pathways & Interactions for C11orf42 Gene

SuperPathways for C11orf42 Gene

No Data Available

Interacting Proteins for C11orf42 Gene

Gene Ontology (GO) - Biological Process for C11orf42 Gene


No data available for Pathways by source and SIGNOR curated interactions for C11orf42 Gene

Drugs & Compounds for C11orf42 Gene

No Compound Related Data Available

Transcripts for C11orf42 Gene

mRNA/cDNA for C11orf42 Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C11orf42 Gene

Chromosome 11 open reading frame 42:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for C11orf42
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf42 Gene

No ASD Table

Relevant External Links for C11orf42 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C11orf42 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf42 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf42 Gene

This gene is overexpressed in Testis (x36.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf42 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf42 Gene:


SOURCE GeneReport for Unigene cluster for C11orf42 Gene:

genes like me logo Genes that share expression patterns with C11orf42: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf42 Gene

Orthologs for C11orf42 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C11orf42 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C11H11orf42 33
  • 99.6 (n)
C11orf42 34
  • 99 (a)
(Canis familiaris)
Mammalia C11orf42 34
  • 90 (a)
C21H11orf42 33
  • 89.99 (n)
(Bos Taurus)
Mammalia C15H11orf42 33
  • 89.09 (n)
C11orf42 34
  • 87 (a)
(Rattus norvegicus)
Mammalia RGD1561034 33
  • 88.19 (n)
(Mus musculus)
Mammalia Gm5901 33 16 34
  • 87.99 (n)
(Monodelphis domestica)
Mammalia C11orf42 34
  • 66 (a)
Species where no ortholog for C11orf42 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf42 Gene

Gene Tree for C11orf42 (if available)
Gene Tree for C11orf42 (if available)

Paralogs for C11orf42 Gene

No data available for Paralogs for C11orf42 Gene

Variants for C11orf42 Gene

Sequence variations from dbSNP and Humsavar for C11orf42 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs117940741 Uncertain significance 6,214,426(+) AGAAC(A/G)GCGTG intron-variant, nc-transcript-variant, downstream-variant-500B, reference, missense
rs1000024554 -- 6,219,523(+) GGGAA(A/G)TAGGT intron-variant
rs1000227170 -- 6,207,848(+) AAGCA(C/G)ATCAG intron-variant
rs1000271879 -- 6,203,136(+) GTCCT(A/G)AAGAG utr-variant-5-prime
rs1000324883 -- 6,225,223(+) CTACA(C/T)AATCT intron-variant

Variation tolerance for C11orf42 Gene

Residual Variation Intolerance Score: 60.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.40; 27.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf42 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for C11orf42 Gene

Disorders for C11orf42 Gene

Relevant External Links for C11orf42

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C11orf42 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf42 Gene

Publications for C11orf42 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60

Products for C11orf42 Gene

Sources for C11orf42 Gene

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