Aliases for C11orf31 Gene
External Ids for C11orf31 Gene
Previous GeneCards Identifiers for C11orf31 Gene
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein mRNAs contains a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
GeneCards Summary for C11orf31 Gene
C11orf31 (Chromosome 11 Open Reading Frame 31) is a Protein Coding gene. Among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. GO annotations related to this gene include poly(A) RNA binding and selenium binding.
UniProtKB/Swiss-Prot for C11orf31 Gene
May be involved in a redox-related process.