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C11orf30 Gene

protein-coding GIFtS: 54

GC11P075833

chromosome 11 open reading frame 30
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EMSY ^¹, ², ⁵
FLJ90741 ^²
GL002 ^²

Descriptions
EMSY protein ^²
chromosome 11 open reading frame 30 ^²

External Ids
HGNC: 18071¹
Entrez Gene: 56946²
UniProtKB: Q7Z589³
Ensembl: ENSG00000158636⁷

Search outside databases for aliases for C11orf30 gene

Previous GC identifers: GC11P075884 GC11P075882

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: EMSY_HUMAN, Q7Z589

Function: Regulator which is able to repress transcription, possibly via its interaction with a

multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2

suggests that it may play a central role in the DNA repair function of BRCA2

Gene Wiki entry for C11orf30

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the C11orf30 gene

Entrez Gene cytogenetic band: 11q13.5 Ensembl cytogenetic band: 11q13.5 HGNC cytogenetic band: 11q13.5

C11orf30 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P075833: (about GC identifiers)

Start:	75,833,717 bp from pter
End:	75,940,237 bp from pter
Size:	106,521 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033927.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: EMSY_HUMAN, Q7Z589 (See protein sequence)

Recommended Name: Protein EMSY

Size: 1322 amino acids; 141468 Da

Subunit: Homodimer. Interacts with the transactivation domain of BRCA2. Interacts with the

chromoshadow domain of CBX1 and with ZMYND11. Does not interact with CBX3 or CBX5

Subcellular location: Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting

that it participates in DNA repair process

Miscellaneous: Was named EMSY by PubMed:14651845 because the protein sequence contains the word

'SISTER', after the first author's sister, who is a breast cancer nurse

PDB structures from and Proteopedia :

1UTU (3D)

1UZ3 (3D)

2FMM (3D)

Secondary accessions: Q4G109 Q8NBU6 Q8TE50 Q9H8I9 Q9NRH0

Alternative splicing: 3 isoforms: Q7Z589-1 Q7Z589-2 Q7Z589-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_064578.2

ENSEMBL proteins:

ENSP00000344688 ENSP00000334130 ENSP00000377102

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EMSY)
	Human Recombinant Proteins from Abnova (C11orf30)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

About this table

Antibodies for C11orf30:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for C11orf30
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (EMSY), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (C11orf30)
	Novus Biologicals Antibodies for C11orf30

Assays for C11orf30:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q7Z589

ProtoNet protein and cluster: Q7Z589

UniProtKB/Swiss-Prot: EMSY_HUMAN, Q7Z589

Similarity: Contains 1 ENT (EMSY N-terminal) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (C11orf30)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (C11orf30)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020193

Applied Biosystems Silencer® siRNAs for C11orf30

Sigma-Aldrich siRNA for C11orf30

Sigma-Aldrich shRNA Panels and shRNA for C11orf30

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for C11orf30
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_020193
Myc/DDK tagged cDNA clone in CMV expression vector: NM_020193
untagged cDNA clones in CMV expression vector (see all 2): BC021688

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_020193

UniProtKB/Swiss-Prot: EMSY_HUMAN, Q7Z589

Function: Regulator which is able to repress transcription, possibly via its interaction with a

multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2

suggests that it may play a central role in the DNA repair function of BRCA2

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for C11orf30

4 Interacting proteins for C11orf30 (ENSP00000334130³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CBX1	ENSP00000225603³	STRING (score=.999)
ZMYND11	ENSP00000370996³	STRING (score=.993)
BRCA2	ENSP00000369497³	STRING (score=.988)
CBX5	ENSP00000209875³	STRING (score=.92)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006281	DNA repair	IEA	--
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0006974	response to DNA damage stimulus	IEA	--
GO:0016568	chromatin modification	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for C11orf30

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (C11orf30)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (C11orf30)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020193

Sigma-Aldrich siRNA for C11orf30

Sigma-Aldrich shRNA Panels and shRNA for C11orf30

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_020193

REFSEQ mRNAs for C11orf30 gene:

NM_020193.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_020193

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020193
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_020193
                                 untagged cDNA clones in CMV expression vector (see all 2): BC021688

Additional cDNA sequence:

AF226047.1 AJ430203.1 AK023651.1 AK125114.1 AK126030.1 AK300400.1 AK304043.1 AK304106.1

AK309621.1 AY070433.1 BC021688.1 BC029375.1 BC033404.1 BC117265.1 BC143370.1 BC143374.1

BC143376.1 BX647398.1 CR609463.1

12 DOTS entries:

DT.211641 DT.102828044 DT.95197020 DT.95366490 DT.105638 DT.430271 DT.101966512 DT.101971716

DT.40113811 DT.95228372 DT.97858752 DT.92421799

24/188 AceView cDNA sequences (see all 188 ):

N95747 AA770420 AI222009 AI091396 W47416 AA279671 AA682866 CR609463

CD629917 BX109175 CD629925 BQ025319 BC029375 BQ025646 CK821861 AA456413

CK821862 BM714176 AI742062 AA970698 BX089439 AK023651 BM470624 R23009

highest scoring ESTs for C11orf30:

AA075423 AA393123 AA399571 AA411901 AA489086 AA705180 AA722931 AA730993 AA770420 AA811588

Unigene Cluster for C11orf30:

Chromosome 11 open reading frame 30

Hs.352588 [show with all ESTs]

Unigene Representative Sequence: NM_020193

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for C11orf30 (see all 7 )

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12	^	13a	·	13b	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19a	·
SP1:													-																		-
SP2:													-										-								-														-
SP3:																																													-
SP4:
SP5:

ExUns:	19b	^	20a	·	20b	^	21	^	22a	·	22b	·	22c
SP1:	-						-
SP2:	-						-
SP3:
SP4:
SP5:	-		-		-		-

About this scheme

ECgene alternative splicing isoforms for C11orf30

3 Ensembl transcripts including schematic representations:

ENST00000343878 ENST00000334736 ENST00000393457

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

C11orf30 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for C11orf30

¹ / ² / ³

15 probe-sets matching C11orf30 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
75292_at²^{, 3}	U95-E	1	1.00	1.00	0.87	0.92	AI379464	0.60	1.00	0.82	1
63025_at²^{, 3}	U95-C	1	1.00	1.00	0.85	1.32	AI742062	0.80	1.00	0.91	1
45136_at²^{, 3}	U95-B	1	0.94	1.00	0.74	0.69	AA075423	1.00	1.00	1.00	1
71479_at²^{, 3}	U95-D	1	0.88	1.00	0.68	1.10	H03776	0.60	1.00	0.82	1
222806_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AK023651	0.80	1.00	0.91	1
222807_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BE549964	0.60	1.00	0.82	1
219012_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_020193	0.60	1.00	0.82	1
242847_at²^{, 3}	U133-B	1	0.73	1.00	--	--	AL525928	0.40	1.00	0.76	1
234669_x_at²^{, 3}	U133-B	1	0.55	1.00	--	--	AJ251708	0.20	1.00	0.72	1
222806_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1569349_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
222807_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
219012_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
242847_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--
234669_x_at²	U133Plus2	1	0.55	1.00	--	--	--	--	--	--	--

GeneDecks C11orf30 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTGGCCAAAG

SOURCE GeneReport for Unigene cluster: Hs.352588

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for C11orf30 gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	LOC476800¹	--	similar to EMSY protein	96.09(n) 98.49(a)	476800 XM_534005.2 XP_534005.2
cow (Bos taurus)	LOC540919¹	--	similar to EMSY protein	95.84(n) 98.01(a)	540919 XM_863841.2 XP_868934.2
mouse (Mus musculus)	2210018M11Rik^{1, 5}	7⁵	RIKEN cDNA 2210018M11 gene^{1, 5}	92.53(n)¹ 95.2(a)¹	233545¹ NM_172280.2¹ NP_758484.2¹ AI451170⁵ AK008751⁵ (see all 22)
zebrafish (Danio rerio)	wufj36b04²	--	wufj36b04	74.03(n)	335889 BC047813.1
fruit fly (Drosophila melanogaster)	CG15356¹	--	CG15356	39.26(n) 27.69(a)	33370 NM_134789.1 NP_608633.1

About this table Species with no ortholog for C11orf30

ENSEMBL Gene Tree for C11orf30

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/449 NCBI SNPs in C11orf30 are shown (see all 449 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 141)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2513513^1,2	A,C,F,H,O	75939181(+)	`TTTCTG/ACTGAG`	1	--	ut3¹ ese³		13	EA NA EU WA	1232
	rs8848^1,2	A,C,F,H	75940300(+)	`GTTCTT/GCTAGG`	1	--	ng3¹		10	MN EU EA WA NA	1106
	rs1044265^1,2	A,C,F,H	75939776(+)	`TTGAAA/GATAAC`	1	--	ut3¹		10	MN EA NA EU WA	2416
	rs2282611^1,2	C,F,H,O	75832494(-)	`TAGGAA/CAGTCA`	1	--	ng5¹		8	EA NA EU	1540
	rs12278256^1,2	C,F,H	75833203(+)	`ATCTGG/TGGGGC`	1	--	ng5¹		4	EU EA WA	412
	rs1954782^1,2	C,H	75904953(+)	`TACCCA/CAATCA`	1	K/Q	mis¹ ese³		4	EU EA WA	418
	rs7947888^1,2	F,H	75940308(+)	`AGGTGA/TTAATG`	1	--	ng3¹		4	EU EA WA	408
	rs17134964^1,2	H	75939822(+)	`ATAAAA/GAGTTC`	1	--	ut3¹		7	NA EU EA WA	548
	rs3753051^1,2	A,C,F,H	75934863(+)	`TCCACT/CGTTGG`	1	T/T	syn¹ ese³		13	EA NA EU WA	1128
	rs11822571^1,2	C,F,H	75933160(+)	`TTCCAG/AACTAA`	1	Q/Q	syn¹ ese³		4	EU EA WA	420

About this table

HapMap Linkage Disequilibrium images for C11orf30 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 608574

UniProtKB/Swiss-Prot: EMSY_HUMAN, Q7Z589

Defects in EMSY may be a cause of sporadic breast cancer and higher-grade ovarian cancers.

Overexpressed through amplification almost exclusively in sporadic breast cancer (13%) and

higher-grade ovarian cancer (17%). Amplification is associated with worse survival, particularly

in node-negative breast cancer, suggesting that it may be of prognostic value

Human Genome Epidemiology Navigator: C11orf30 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/20 PubMed articles for C11orf30 gene (see all 20 ):

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. (PubMed id 15947784)^{1, 3, 4} Ekblad C.M.S.... Itzhaki L.S. (2005)
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. (PubMed id 14651845)^{1, 3, 4} Hughes-Davies L.... Kouzarides T. (2003)
Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding. (PubMed id 16615912)^{3, 4} Huang Y.... Xu R.-M. (2006)
Crystal structure of the ENT domain of human EMSY. (PubMed id 15978617)^{3, 4} Chavali G.B.... Doherty A.J. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas. (PubMed id 16236351)^{1, 3} Brown L.A....Huntsman D. (2006)
Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. (PubMed id 18950845)³ Vega A....Carracedo A. (2009)
Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. (PubMed id 19124506)³ Mavaddat N....Pharoah P.D. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 56946	HGNC: 18071	AceView: C11orf30	Ensembl:ENSG00000158636	euGenes: HUgn56946
ECgene: C11orf30	H-InvDB: C11orf30

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for C11orf30	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for C11orf30
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for C11orf30:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for C11orf30-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for C11orf30		Antibodies for C11orf30
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for C11orf30		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (C11orf30)
	Antibodies (C11orf30)
	Chimera RNAi (C11orf30)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (EMSY)
	Antibodies (EMSY)

Search OriGene for C11orf30

Search Tocris compounds for C11orf30

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for C11orf30

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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C11orf30 Gene at Home site.
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C11orf30 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for C11orf30

Summaries
for C11orf30

Genomic Location
for C11orf30

Proteins
for C11orf30

Protein Domains/
Families
for C11orf30

Gene Function
for C11orf30

Pathways & Interactions
for C11orf30

Drugs & Compounds
for C11orf30

Transcripts
for C11orf30

Expression
for C11orf30

Orthologs
for C11orf30

Paralogs
for C11orf30

SNPs/Variants
for C11orf30

Disorders & Mutations
for C11orf30

Medical News
for C11orf30

Publications
for C11orf30

Search for C11orf30

Genome Databases showing C11orf30

Other Databases showing C11orf30

Specialized Databases showing C11orf30

Licensable Technologies
for C11orf30

Services
for C11orf30

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

C11orf30 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor C11orf30

Summariesfor C11orf30

Genomic Locationfor C11orf30

Proteinsfor C11orf30

Protein Domains/Familiesfor C11orf30

Gene Functionfor C11orf30

Pathways & Interactionsfor C11orf30

Drugs & Compoundsfor C11orf30

Transcriptsfor C11orf30

Expression for C11orf30

Orthologsfor C11orf30

Paralogsfor C11orf30

SNPs/Variantsfor C11orf30

Disorders & Mutationsfor C11orf30

Medical Newsfor C11orf30

Publicationsfor C11orf30

Search for C11orf30

Genome Databases showing C11orf30

Other Databases showing C11orf30

Specialized Databases showing C11orf30

Licensable Technologiesfor C11orf30

Servicesfor C11orf30

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for C11orf30

Summaries
for C11orf30

Genomic Location
for C11orf30

Proteins
for C11orf30

Protein Domains/
Families
for C11orf30

Gene Function
for C11orf30

Pathways & Interactions
for C11orf30

Drugs & Compounds
for C11orf30

Transcripts
for C11orf30

Expression
for C11orf30

Orthologs
for C11orf30

Paralogs
for C11orf30

SNPs/Variants
for C11orf30

Disorders & Mutations
for C11orf30

Medical News
for C11orf30

Publications
for C11orf30

Licensable Technologies
for C11orf30

Services
for C11orf30