C11orf24 Gene
protein-coding GIFtS: 41
GCID: GC11M068028
|
|
chromosome 11 open reading frame 24
| |
Aliases
for C11orf24 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 11 Open Reading Frame 241 2 | | DM4E31 2 | | Uncharacterized Protein C11orf242 | | Protein DM4E33 |
Export aliases for C11orf24 gene to outside databasesPrevious GC identifers: GC11M070551 GC11M069725 GC11M068278 GC11M067804 GC11M067787 GC11M064363 |
Summaries
for C11orf24 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C11orf24 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C11orf24 gene promoter:
HFH-3 Max1 FOXI1 PPAR-alpha NRF-2 POU2F1 POU2F1a c-Myc Ik-1 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for C11orf24
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf24 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.2C11orf24 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M068028: view genomic region
(about GC identifiers)
Start:
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68,028,803 bp from pter |
End:
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68,039,469 bp from pter |
Size:
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10,667 bases |
Orientation:
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minus strand |
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Proteins
for C11orf24 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CK024_HUMAN, Q96F05 (See
protein sequence)Recommended Name: Uncharacterized protein C11orf24 precursor Size: 449 amino acids; 46101 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: Q9H2K4Explore the universe of human proteins at neXtProt for C11orf24: NX_Q96F05
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96F05
C11orf24 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_071733.1
ENSEMBL proteins: ENSP00000307264 ENSP00000434144 ENSP00000436765
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
C11orf24 for ontologies About GeneDecksing
C11orf24 Antibody Products:
Assay Products for C11orf24: |
Protein
Domains /
Families
for C11orf24 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96F05 |
Function
for C11orf24 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for C11orf24 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf24 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf24 |
2 GenomeRNAi human phenotypes for C11orf24:
|
Pathways & Interactions
for C11orf24 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C11orf24
|
Drugs & Compounds
for C11orf24 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C11orf24
Search CenterWatch for drugs/clinical trials and news about C11orf24 / CK024
|
Transcripts
for C11orf24 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C11orf24 gene: NM_022338.3 Unigene Cluster for C11orf24: Chromosome 11 open reading frame 24 Hs.303025 [show with all ESTs]Unigene Representative Sequence: NM_0223389 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000304271(uc001onr.4) ENST00000531745 ENST00000533310 ENST00000530166
ENST00000527280 ENST00000529590 ENST00000532534 ENST00000532969 ENST00000529339
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C11orf24 (NM_022338) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf24 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf24 |
Additional cDNA sequence: AF264781.1 AF370372.1 AY358754.1 BC011765.2 10 DOTS entries: DT.412957 DT.91762893 DT.100762109 DT.100781735 DT.120683399 DT.95184073 DT.91762891 DT.91957235 DT.100784332 DT.99938140 24/241 AceView cDNA sequences (see all 241): BM826469 BG026437 AW848651 BI913846 BF970591 CR600976 BX426288 BM977122 CA455075 CR604388 AW376739 BX340083 CR615151 CR595092 AF264781 BX363160 BC011765 BX336759 CR625680 CR623094 AI086975 AY358754 AW376737 BQ892712
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for C11orf24 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C11orf24
|
Expression
for C11orf24 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C11orf24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCACTAAAG
About this image
See C11orf24 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C11orf24
SOURCE GeneReport for Unigene cluster: Hs.303025
UniProtKB/Swiss-Prot: CK024_HUMAN, Q96F05Tissue specificity: Highest expression in heart, placenta, liver, pancreas and colon. Also detected in brain, lung,skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine. Lowest expression in thymus andleukocytes
SABiosciences Custom PCR Arrays for C11orf24
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf24
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C11orf24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf24 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf24 |
Orthologs
for C11orf24 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C11orf24 gene from 4/10 species (see all 10) About this table
ENSEMBL Gene Tree for C11orf24 (if available)
TreeFam Gene Tree for C11orf24 (if available) |
Paralogs
for C11orf24 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C11orf24 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C11orf24 (68028803 - 68039469 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C11orf24
1 Indel: 101246 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf24 |
|
Disorders
/ Diseases
for C11orf24 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C11orf24 for disorders About GeneDecksing
OMIM gene information: 610880
OMIM disorders: --
1  disease for C11orf24: About MalaCardsprostatitis
Export disorders for C11orf24 gene to outside databases
|
Publications
for C11orf24 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C11orf24 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C11orf24) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13. (PubMed id 11401438)1, 2, 3 Twells R.C....Hess J.F. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for C11orf24 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C11orf24 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C11orf24 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C11orf24 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C11orf24 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C11orf24 gene:
Search GeneIP for patents involving C11orf24
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C11orf24 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C11orf24 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C11orf24 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf24 | | | OriGene Protein Over-expression Lysate for C11orf24 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C11orf24 | | OriGene 3'-UTR Clone for C11orf24 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf24 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C11orf24 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf24 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf24 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C11orf24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf24 |
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 | | | C11orf24 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf24 |
|  |  |  | | | | Search ThermoFisher Antibodies for C11orf24 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf24 |
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