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Aliases for C11orf16 Gene

Aliases for C11orf16 Gene

  • Chromosome 11 Open Reading Frame 16 2 3 5

External Ids for C11orf16 Gene

Previous GeneCards Identifiers for C11orf16 Gene

  • GC11P009967
  • GC11M009632
  • GC11M008980
  • GC11M008905
  • GC11M008898
  • GC11M008611

Summaries for C11orf16 Gene

GeneCards Summary for C11orf16 Gene

C11orf16 (Chromosome 11 Open Reading Frame 16) is a Protein Coding gene.

Gene Wiki entry for C11orf16 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf16 Gene

Genomics for C11orf16 Gene

Regulatory Elements for C11orf16 Gene

Enhancers for C11orf16 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C11orf16 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf16 Gene

Chromosome:
11
Start:
8,920,076 bp from pter
End:
8,933,006 bp from pter
Size:
12,931 bases
Orientation:
Minus strand

Genomic View for C11orf16 Gene

Genes around C11orf16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf16 Gene

Proteins for C11orf16 Gene

  • Protein details for C11orf16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQ32-CK016_HUMAN
    Recommended name:
    Uncharacterized protein C11orf16
    Protein Accession:
    Q9NQ32
    Secondary Accessions:
    • Q53FB2
    • Q8N6Y9

    Protein attributes for C11orf16 Gene

    Size:
    467 amino acids
    Molecular mass:
    51609 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C11orf16 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C11orf16 Gene

Proteomics data for C11orf16 Gene at MOPED

Post-translational modifications for C11orf16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf16 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C11orf16 Gene

Domains & Families for C11orf16 Gene

Protein Domains for C11orf16 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C11orf16: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C11orf16 Gene

Function for C11orf16 Gene

genes like me logo Genes that share phenotypes with C11orf16: view

Animal Model Products

CRISPR Products

miRNA for C11orf16 Gene

miRTarBase miRNAs that target C11orf16

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf16 Gene

Localization for C11orf16 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C11orf16 Gene COMPARTMENTS Subcellular localization image for C11orf16 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C11orf16 Gene

Pathways & Interactions for C11orf16 Gene

SuperPathways for C11orf16 Gene

No Data Available

Interacting Proteins for C11orf16 Gene

Selected Interacting proteins: Q9NQ32-CK016_HUMAN for C11orf16 Gene via I2D

Symbol External ID(s) Details
EWSR1
--
--

Gene Ontology (GO) - Biological Process for C11orf16 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf16 Gene

Drugs & Compounds for C11orf16 Gene

No Compound Related Data Available

Transcripts for C11orf16 Gene

mRNA/cDNA for C11orf16 Gene

Unigene Clusters for C11orf16 Gene

Chromosome 11 open reading frame 16:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf16 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8
SP1: - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5: - -
SP6:

Relevant External Links for C11orf16 Gene

GeneLoc Exon Structure for
C11orf16
ECgene alternative splicing isoforms for
C11orf16

Expression for C11orf16 Gene

mRNA expression in normal human tissues for C11orf16 Gene

mRNA differential expression in normal tissues according to GTEx for C11orf16 Gene

This gene is overexpressed in Fallopian Tube (x11.0), Cervix - Endocervix (x8.5), Testis (x8.0), and Lung (x6.7).

Protein differential expression in normal tissues from HIPED for C11orf16 Gene

This gene is overexpressed in Pancreatic juice (54.3) and Adipocyte (14.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C11orf16 Gene



SOURCE GeneReport for Unigene cluster for C11orf16 Gene Hs.277349

genes like me logo Genes that share expression patterns with C11orf16: view

Protein tissue co-expression partners for C11orf16 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C11orf16 Gene

Orthologs for C11orf16 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf16 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C15H11orf16 35
  • 79.18 (n)
  • 67.81 (a)
C11ORF16 36
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C21H11orf16 35
  • 77.9 (n)
  • 63.71 (a)
C11orf16 36
  • 60 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC051019 35
  • 73.37 (n)
  • 62.81 (a)
BC051019 16
BC051019 36
  • 62 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C11H11orf16 35
  • 98.5 (n)
  • 97 (a)
C11orf16 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC499240 35
  • 74.49 (n)
  • 66.67 (a)
oppossum
(Monodelphis domestica)
Mammalia C11orf16 36
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves C11ORF16 35
  • 51.51 (n)
  • 37.69 (a)
C11orf16 36
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C11orf16 36
  • 56 (a)
OneToOne
Species with no ortholog for C11orf16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C11orf16 Gene

ENSEMBL:
Gene Tree for C11orf16 (if available)
TreeFam:
Gene Tree for C11orf16 (if available)

Paralogs for C11orf16 Gene

No data available for Paralogs for C11orf16 Gene

Variants for C11orf16 Gene

Sequence variations from dbSNP and Humsavar for C11orf16 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2568076 - 8,927,068(-) CATTC(C/G/T)TCTCT nc-transcript-variant, reference, missense
rs11042127 - 8,926,039(+) CTGGA(C/G/T)CCCAC nc-transcript-variant, reference, missense
rs2246878 -- 8,928,057(-) GGTGG(G/T)GGGCT intron-variant
rs2247038 -- 8,929,986(-) CACAC(C/T)ACCAC intron-variant
rs7124102 -- 8,930,726(+) TACTT(C/T)GTGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C11orf16 Gene

Variant ID Type Subtype PubMed ID
nsv7215 OTHER Inversion 18451855
nsv499766 OTHER Inversion 21111241
essv24306 CNV CNV 17122850
nsv435923 CNV Deletion 17901297
nsv832062 CNV Loss 17160897

Variation tolerance for C11orf16 Gene

Residual Variation Intolerance Score: 76.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.11; 87.71% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C11orf16 Gene

Disorders for C11orf16 Gene

Relevant External Links for C11orf16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf16

No disorders were found for C11orf16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf16 Gene

Publications for C11orf16 Gene

  1. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PMID: 11528127) Amid C. … Schmidt E.R. (Cytogenet. Cell Genet. 2001) 2 3 4 67
  2. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for C11orf16 Gene

Sources for C11orf16 Gene

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