C11orf16 Gene
protein-coding GIFtS: 41
GCID: GC11M008941
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chromosome 11 open reading frame 16
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Aliases
for C11orf16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 11 Open Reading Frame 161 2 | | Uncharacterized Protein C11orf162 |
Export aliases for C11orf16 gene to outside databasesPrevious GC identifers: GC11P009967 GC11M009632 GC11M008980 GC11M008905 GC11M008898 GC11M008611 |
Summaries
for C11orf16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for C11orf16
|
Genomic Views
for C11orf16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C11orf16 gene promoter:
ER-alpha AML1a AP-1 ATF-2 AP-4 NRSF form 2 RORalpha1 COMP1 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for C11orf16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.3 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.3C11orf16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M008941: view genomic region
(about GC identifiers)
Start:
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8,941,623 bp from pter |
End:
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8,954,553 bp from pter |
Size:
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12,931 bases |
Orientation:
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minus strand |
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Proteins
for C11orf16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CK016_HUMAN, Q9NQ32 (See
protein sequence)Recommended Name: Uncharacterized protein C11orf16 Size: 467 amino acids; 51609 Da
Secondary accessions: Q53FB2 Q8N6Y9Alternative splicing: 2 isoforms: Q9NQ32-1 Q9NQ32-2 Explore the universe of human proteins at neXtProt for C11orf16: NX_Q9NQ32
C11orf16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065694.2
ENSEMBL proteins: ENSP00000436818 ENSP00000318999 ENSP00000437069 ENSP00000436584
Human Recombinant Protein Products:
C11orf16 Antibody Products:
Assay Products for C11orf16: |
Protein
Domains /
Families
for C11orf16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9NQ32 |
Function
for C11orf16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C11orf16 (NM_020643) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf16 |
5 GenomeRNAi human phenotypes for C11orf16:
|
Pathways & Interactions
for C11orf16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C11orf16
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for C11orf16 (Q9NQ323 ENSP000003189994) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C11orf16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C11orf16
Search CenterWatch for drugs/clinical trials and news about C11orf16 / CK016
|
Transcripts
for C11orf16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C11orf16 gene: NM_020643.2 Unigene Cluster for C11orf16: Chromosome 11 open reading frame 16 Hs.277349 [show with all ESTs]Unigene Representative Sequence: AK0744556 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000525780 ENST00000326053(uc001mhb.4 uc001mhc.4) ENST00000528998
ENST00000528830 ENST00000526227 ENST00000527607
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C11orf16 (NM_020643) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C11orf16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf16 |
Additional cDNA sequence: AK074455.1 AK223377.1 BC027865.1 4 DOTS entries: DT.97807638 DT.75100926 DT.100643007 DT.91675523 16 AceView cDNA sequences: CD171707 AI202945 AI697899 AI916300 BC027865 NM_020643 AI688557 BI770174 BX282735 AI799116 BM983753 CA310676 AI358494 BM978791 AK074455 AW293458
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for C11orf16 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 |
|---|
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| SP1: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C11orf16
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Expression
for C11orf16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C11orf16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTGACATTT
About this image
See C11orf16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C11orf16
SOURCE GeneReport for Unigene cluster: Hs.277349
SABiosciences Custom PCR Arrays for C11orf16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C11orf16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf16 |
Orthologs
for C11orf16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C11orf16 gene from 3/8 species (see all 8) About this table
ENSEMBL Gene Tree for C11orf16 (if available)
TreeFam Gene Tree for C11orf16 (if available) |
Paralogs
for C11orf16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C11orf16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C11orf16 (8941623 - 8954553 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for C11orf16
1 CNV: 3837 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for C11orf16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C11orf16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C11orf16 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C11orf16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PubMed id 11528127)1, 2, 3 Amid C.... Schmidt E.R. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for C11orf16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C11orf16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C11orf16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C11orf16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C11orf16 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C11orf16 gene:
Search GeneIP for patents involving C11orf16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C11orf16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C11orf16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C11orf16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C11orf16 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C11orf16 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C11orf16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C11orf16 | | OriGene Custom Protein Services for C11orf16 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C11orf16 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C11orf16 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C11orf16 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C11orf16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C11orf16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C11orf16 |
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 | | | C11orf16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C11orf16 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C11orf16 |
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