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Aliases for C11orf1 Gene

Aliases for C11orf1 Gene

  • Chromosome 11 Open Reading Frame 1 2 3 5

External Ids for C11orf1 Gene

Previous GeneCards Identifiers for C11orf1 Gene

  • GC11U990011
  • GC11P111783
  • GC11P111287
  • GC11P111255
  • GC11P111749
  • GC11P107673

Summaries for C11orf1 Gene

GeneCards Summary for C11orf1 Gene

C11orf1 (Chromosome 11 Open Reading Frame 1) is a Protein Coding gene.

Gene Wiki entry for C11orf1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf1 Gene

Genomics for C11orf1 Gene

Regulatory Elements for C11orf1 Gene

Promoters for C11orf1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around C11orf1 on UCSC Golden Path with GeneCards custom track

Genomic Location for C11orf1 Gene

Chromosome:
11
Start:
111,878,935 bp from pter
End:
111,885,975 bp from pter
Size:
7,041 bases
Orientation:
Plus strand

Genomic View for C11orf1 Gene

Genes around C11orf1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf1 Gene

Proteins for C11orf1 Gene

  • Protein details for C11orf1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H5F2-CK001_HUMAN
    Recommended name:
    UPF0686 protein C11orf1
    Protein Accession:
    Q9H5F2
    Secondary Accessions:
    • Q6I9X7
    • Q9NQC6

    Protein attributes for C11orf1 Gene

    Size:
    150 amino acids
    Molecular mass:
    17785 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf1 Gene

Proteomics data for C11orf1 Gene at MOPED

Post-translational modifications for C11orf1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C11orf1 Gene

No data available for DME Specific Peptides for C11orf1 Gene

Domains & Families for C11orf1 Gene

Protein Domains for C11orf1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C11orf1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H5F2

UniProtKB/Swiss-Prot:

CK001_HUMAN :
  • Belongs to the UPF0686 family.
Family:
  • Belongs to the UPF0686 family.
genes like me logo Genes that share domains with C11orf1: view

No data available for Gene Families for C11orf1 Gene

Function for C11orf1 Gene

genes like me logo Genes that share phenotypes with C11orf1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C11orf1 Gene

Localization for C11orf1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C11orf1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C11orf1 Gene COMPARTMENTS Subcellular localization image for C11orf1 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 1
extracellular 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for C11orf1 Gene

Pathways & Interactions for C11orf1 Gene

SuperPathways for C11orf1 Gene

No Data Available

Interacting Proteins for C11orf1 Gene

Selected Interacting proteins: Q9H5F2-CK001_HUMAN for C11orf1 Gene via MINT I2D

Symbol External ID(s) Details
SETDB1

Gene Ontology (GO) - Biological Process for C11orf1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C11orf1 Gene

Drugs & Compounds for C11orf1 Gene

No Compound Related Data Available

Transcripts for C11orf1 Gene

Unigene Clusters for C11orf1 Gene

Chromosome 11 open reading frame 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: -
SP2: - - - -
SP3: - -
SP4:

Relevant External Links for C11orf1 Gene

GeneLoc Exon Structure for
C11orf1
ECgene alternative splicing isoforms for
C11orf1

Expression for C11orf1 Gene

mRNA expression in normal human tissues for C11orf1 Gene

SOURCE GeneReport for Unigene cluster for C11orf1 Gene Hs.17546

genes like me logo Genes that share expression patterns with C11orf1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C11orf1 Gene

Orthologs for C11orf1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC101906594 35
  • 92.89 (n)
  • 88.97 (a)
-- 36
  • 75 (a)
OneToMany
-- 36
  • 78 (a)
OneToMany
dog
(Canis familiaris)
Mammalia C5H11orf1 35
  • 90.16 (n)
  • 88.59 (a)
C11orf1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110032A03Rik 35
  • 83.67 (n)
  • 79.19 (a)
1110032A03Rik 16
1110032A03Rik 36
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564937 35
  • 86.96 (n)
  • 84.06 (a)
oppossum
(Monodelphis domestica)
Mammalia C11orf1 36
  • 56 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C11orf1 36
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves C24H11ORF1 35
  • 65.55 (n)
  • 64.71 (a)
C11orf1 36
  • 53 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C11orf1 36
  • 58 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC797203 35
  • 57.07 (n)
  • 52.27 (a)
C11orf1 36
  • 42 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 38 (a)
OneToOne
Species with no ortholog for C11orf1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf1 Gene

ENSEMBL:
Gene Tree for C11orf1 (if available)
TreeFam:
Gene Tree for C11orf1 (if available)

Paralogs for C11orf1 Gene

No data available for Paralogs for C11orf1 Gene

Variants for C11orf1 Gene

Sequence variations from dbSNP and Humsavar for C11orf1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs11540721 - 111,882,467(-) AAACT(G/T)GGACA reference, missense
rs3180820 - 111,882,577(+) GTGCA(C/G)CCCAA reference, missense
rs9280 - 111,882,441(+) TGAAG(C/T)GTGGA reference, missense
rs594098 -- 111,883,332(-) ggtta(C/T)aggtg intron-variant
rs1045282 -- 111,883,850(+) AAGTC(A/C)ACTTA reference, synonymous-codon, missense

Structural Variations from Database of Genomic Variants (DGV) for C11orf1 Gene

Variant ID Type Subtype PubMed ID
nsv832269 CNV Loss 17160897

Variation tolerance for C11orf1 Gene

Residual Variation Intolerance Score: 72.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.06; 50.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf1 Gene

HapMap Linkage Disequilibrium report
C11orf1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf1 Gene

Disorders for C11orf1 Gene

Relevant External Links for C11orf1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf1

No disorders were found for C11orf1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf1 Gene

Publications for C11orf1 Gene

  1. Characterization of five novel human genes in the 11q13-q22 region. (PMID: 10873569) O'Brien K.P. … Dumanski J.P. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 67
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for C11orf1 Gene

Sources for C11orf1 Gene

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