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Aliases for C11orf1 Gene

Aliases for C11orf1 Gene

  • Chromosome 11 Open Reading Frame 1 2 3 5

External Ids for C11orf1 Gene

Previous GeneCards Identifiers for C11orf1 Gene

  • GC11U990011
  • GC11P111783
  • GC11P111287
  • GC11P111255
  • GC11P111749
  • GC11P107673

Summaries for C11orf1 Gene

GeneCards Summary for C11orf1 Gene

C11orf1 (Chromosome 11 Open Reading Frame 1) is a Protein Coding gene.

Gene Wiki entry for C11orf1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C11orf1 Gene

Genomics for C11orf1 Gene

Regulatory Elements for C11orf1 Gene

Enhancers for C11orf1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G111934 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.6 +61.1 61130 11.8 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 PPP2R1B SDHD C11orf52 HSPB2 HSPB2-C11orf52 TIMM8B FDXACB1 C11orf1 ALG9 C11orf57
GH11G111917 1.3 Ensembl ENCODE 11 +39.8 39811 2.3 FOXA2 ATF1 MLX SIN3A ARID4B DMAP1 ZNF48 YY1 ETS1 TCF12 PPP2R1B FDXACB1 C11orf1 ALG9 C11orf52 SDHD CRYAB LOC105369494
GH11G111844 1.2 Ensembl ENCODE dbSUPER 10.7 -32.6 -32570 3.1 PKNOX1 MAX FEZF1 ZNF316 ZNF600 FOS MAFK NFE2L2 ZNF10 CEBPB PPP2R1B ALG9 SIK2 FDXACB1 C11orf1 ENSG00000254980 GNG5P3 ALG9-IT1
GH11G112016 1.1 Ensembl ENCODE 10.2 +138.2 138178 2.0 PKNOX1 FOXA2 ATF1 RAD21 RARA KAT2B GATA4 GATA2 CBX5 FOS PIH1D2 C11orf57 SDHD TIMM8B C11orf1 FDXACB1 ALG9 ENSG00000255334 GC11M112018
GH11G111573 1.1 Ensembl ENCODE dbSUPER 10 -304.8 -304825 1.4 ZNF664 RNF2 ZSCAN4 ZNF398 YY1 NR2F2 SIK2 LAYN PPP2R1B ALG9 FDXACB1 C11orf1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C11orf1 on UCSC Golden Path with GeneCards custom track

Promoters for C11orf1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000044927 65 1601 HDGF PKNOX1 MLX CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for C11orf1 Gene

Chromosome:
11
Start:
111,878,935 bp from pter
End:
111,885,975 bp from pter
Size:
7,041 bases
Orientation:
Plus strand

Genomic View for C11orf1 Gene

Genes around C11orf1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C11orf1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C11orf1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C11orf1 Gene

Proteins for C11orf1 Gene

  • Protein details for C11orf1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H5F2-CK001_HUMAN
    Recommended name:
    UPF0686 protein C11orf1
    Protein Accession:
    Q9H5F2
    Secondary Accessions:
    • Q6I9X7
    • Q9NQC6

    Protein attributes for C11orf1 Gene

    Size:
    150 amino acids
    Molecular mass:
    17785 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C11orf1 Gene

Post-translational modifications for C11orf1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C11orf1 Gene

Domains & Families for C11orf1 Gene

Protein Domains for C11orf1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for C11orf1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H5F2

UniProtKB/Swiss-Prot:

CK001_HUMAN :
  • Belongs to the UPF0686 family.
Family:
  • Belongs to the UPF0686 family.
genes like me logo Genes that share domains with C11orf1: view

No data available for Gene Families for C11orf1 Gene

Function for C11orf1 Gene

Gene Ontology (GO) - Molecular Function for C11orf1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with C11orf1: view
genes like me logo Genes that share phenotypes with C11orf1: view

Animal Models for C11orf1 Gene

MGI Knock Outs for C11orf1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for C11orf1 Gene

Localization for C11orf1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C11orf1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C11orf1 gene
Compartment Confidence
nucleus 5
mitochondrion 2
extracellular 1
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for C11orf1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with C11orf1: view

Pathways & Interactions for C11orf1 Gene

SuperPathways for C11orf1 Gene

No Data Available

Interacting Proteins for C11orf1 Gene

Selected Interacting proteins: Q9H5F2-CK001_HUMAN for C11orf1 Gene via IID

Symbol External ID(s) Details
SETDB1

Gene Ontology (GO) - Biological Process for C11orf1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with C11orf1: view

No data available for Pathways by source and SIGNOR curated interactions for C11orf1 Gene

Drugs & Compounds for C11orf1 Gene

No Compound Related Data Available

Transcripts for C11orf1 Gene

Unigene Clusters for C11orf1 Gene

Chromosome 11 open reading frame 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C11orf1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: -
SP2: - - - -
SP3: - -
SP4:

Relevant External Links for C11orf1 Gene

GeneLoc Exon Structure for
C11orf1
ECgene alternative splicing isoforms for
C11orf1

Expression for C11orf1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C11orf1 Gene

NURSA nuclear receptor signaling pathways regulating expression of C11orf1 Gene:

C11orf1

SOURCE GeneReport for Unigene cluster for C11orf1 Gene:

Hs.17546

Evidence on tissue expression from TISSUES for C11orf1 Gene

  • Lung(4.2)
genes like me logo Genes that share expression patterns with C11orf1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for C11orf1 Gene

Orthologs for C11orf1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C11orf1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC101906594 34
  • 92.89 (n)
-- 35
  • 78 (a)
OneToMany
-- 35
  • 75 (a)
OneToMany
dog
(Canis familiaris)
Mammalia C5H11orf1 34
  • 90.16 (n)
C11orf1 35
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564937 34
  • 86.96 (n)
mouse
(Mus musculus)
Mammalia 1110032A03Rik 34 16 35
  • 83.67 (n)
chimpanzee
(Pan troglodytes)
Mammalia C11orf1 35
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C11orf1 35
  • 56 (a)
OneToOne
chicken
(Gallus gallus)
Aves C24H11ORF1 34
  • 65.55 (n)
C11orf1 35
  • 53 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C11orf1 35
  • 58 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC797203 34
  • 57.07 (n)
C11orf1 35
  • 42 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 38 (a)
OneToOne
Species where no ortholog for C11orf1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C11orf1 Gene

ENSEMBL:
Gene Tree for C11orf1 (if available)
TreeFam:
Gene Tree for C11orf1 (if available)

Paralogs for C11orf1 Gene

No data available for Paralogs for C11orf1 Gene

Variants for C11orf1 Gene

Sequence variations from dbSNP and Humsavar for C11orf1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000266546 -- 111,879,973(+) TAGTT(G/T)AGTTT intron-variant, upstream-variant-2KB
rs1001322959 -- 111,879,458(+) GTTCT(C/G)GGTGA upstream-variant-2KB, utr-variant-5-prime
rs1002155394 -- 111,884,162(+) GGTGT(C/T)GTAGA downstream-variant-500B
rs1002834833 -- 111,884,478(+) CAAAA(A/C)AAAAA downstream-variant-500B
rs1003034139 -- 111,878,610(+) TGCGT(C/G)CACAA intron-variant, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C11orf1 Gene

Variant ID Type Subtype PubMed ID
esv3627745 CNV gain 21293372
nsv832269 CNV loss 17160897

Variation tolerance for C11orf1 Gene

Residual Variation Intolerance Score: 72.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.06; 50.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C11orf1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C11orf1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C11orf1 Gene

Disorders for C11orf1 Gene

Relevant External Links for C11orf1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C11orf1

No disorders were found for C11orf1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C11orf1 Gene

Publications for C11orf1 Gene

  1. Characterization of five novel human genes in the 11q13-q22 region. (PMID: 10873569) O'Brien K.P. … Dumanski J.P. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64

Products for C11orf1 Gene

Sources for C11orf1 Gene

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