C10orf99 Gene
protein-coding GIFtS: 36
GCID: GC10P085923
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chromosome 10 open reading frame 99
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Aliases
for C10orf99 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 10 Open Reading Frame 991 2 | | RLLV18331 2 | | UNQ18331 2 | | Em:AC022389.21 | | FLJ217631 | | Putative Uncharacterized Protein C10orf992 |
Export aliases for C10orf99 gene to outside databasesPrevious GC identifers: GC10P085590 GC10P079779 |
Summaries
for C10orf99 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C10orf99 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C10orf99 gene promoter:
p53 HOXA3 AP-1 CUTL1 HNF-4alpha1 POU2F1 POU2F1a Pax-4a LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C10orf99
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf99 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q23.1 Ensembl cytogenetic band: 10q23.1 HGNC cytogenetic band: 10q23.2C10orf99 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P085923: view genomic region
(about GC identifiers)
Start:
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85,933,494 bp from pter |
End:
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85,945,050 bp from pter |
Size:
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11,557 bases |
Orientation:
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plus strand |
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Proteins
for C10orf99 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CJ099_HUMAN, Q6UWK7 (See
protein sequence)Recommended Name: Putative uncharacterized protein C10orf99 precursor Size: 81 amino acids; 9173 Da
Subcellular location: Secreted (Potential)Explore the universe of human proteins at neXtProt for C10orf99: NX_Q6UWK7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6UWK7
C10orf99 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_997256.1
ENSEMBL proteins: ENSP00000361199
Human Recombinant Protein Products for C10orf99:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
C10orf99 for ontologies About GeneDecksing
C10orf99 Antibody Products:
Assay Products for C10orf99: |
Protein
Domains /
Families
for C10orf99 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6UWK7 |
Function
for C10orf99 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 GenomeRNAi human phenotype for C10orf99:
1 MGI phenotypic allele  for 2610528A11Rik (no phenotypes)
C10orf99 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out 2610528A11Riktm1Lex for C10orf99
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C10orf99 (NM_207373) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf99 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C10orf99 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf99 |
|
Pathways & Interactions
for C10orf99 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C10orf99
|
Drugs & Compounds
for C10orf99 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C10orf99
Search CenterWatch for drugs/clinical trials and news about C10orf99 / CJ099
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Transcripts
for C10orf99 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C10orf99 gene: NM_207373.2 Unigene Cluster for C10orf99: Chromosome 10 open reading frame 99 Hs.298713 [show with all ESTs]Unigene Representative Sequence: BE8995802 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372126(uc001kcu.3) ENST00000472542
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C10orf99 (NM_207373) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf99 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C10orf99 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf99
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C10orf99 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf99 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf99 |
Additional cDNA sequence: AY358751.1 BC126978.1 BC126999.1 1 DOTS entry: DT.91749059 24/44 AceView cDNA sequences (see all 44): BX111944 AY358751 BQ189412 AI246768 AI339648 NM_207373 CK299548 AI720988 AI983767 AW351839 AI833297 AA535314 AA857922 AI832391 AI948903 AA422178 AI813445 AI304380 AW134688 AI283185 AA587764 AI336470 AA553959 AA534511
GeneLoc Exon Structure
|
Expression
for C10orf99 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C10orf99 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTCTGCTGG
About this image
See C10orf99 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C10orf99
SOURCE GeneReport for Unigene cluster: Hs.298713
SABiosciences Custom PCR Arrays for C10orf99
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf99
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C10orf99 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf99 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf99 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf99 |
Orthologs
for C10orf99 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C10orf99 gene from 1/2 species (see all 2) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
2610528A11Rik5 |
RIKEN cDNA 2610528A11 gene |
-- |
|
14 (21.29 cM) 37102140 |
ENSEMBL Gene Tree for C10orf99 (if available)
TreeFam Gene Tree for C10orf99 (if available) |
Paralogs
for C10orf99 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C10orf99 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C10orf99 (85933494 - 85945050 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C10orf99: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf99 |
|
Disorders
/ Diseases
for C10orf99 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for C10orf99 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C10orf99 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C10orf99) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for C10orf99 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing C10orf99 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C10orf99 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf99 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C10orf99 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C10orf99 gene:
Search GeneIP for patents involving C10orf99
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C10orf99 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C10orf99 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C10orf99 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf99 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C10orf99 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf99 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C10orf99 | | OriGene Custom Protein Services for C10orf99 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C10orf99 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf99 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf99 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C10orf99 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf99 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf99 |
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 | | | C10orf99 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf99 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C10orf99 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat C10orf99 |
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