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Aliases for C10orf91 Gene

Aliases for C10orf91 Gene

  • Chromosome 10 Open Reading Frame 91 2 3 5
  • Uncharacterized Protein C10orf91 3
  • BA432J24.4 3

External Ids for C10orf91 Gene

Previous GeneCards Identifiers for C10orf91 Gene

  • GC10P133694
  • GC10P134108
  • GC10P134257
  • GC10P127810

Summaries for C10orf91 Gene

GeneCards Summary for C10orf91 Gene

C10orf91 (Chromosome 10 Open Reading Frame 91) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf91 Gene

Genomics for C10orf91 Gene

Regulatory Elements for C10orf91 Gene

Enhancers for C10orf91 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F132392 0.9 FANTOM5 Ensembl ENCODE 18.9 -35.9 -35925 32.2 HDGF PKNOX1 ARID4B SIN3A YBX1 DMAP1 ZNF207 ZNF548 FOS DEK TUBGCP2 ENSG00000235245 C10orf91 STK32C LOC105378568 PWWP2B LRRC27 LINC01164 CALY DPYSL4
GH10F132443 1.2 FANTOM5 ENCODE 12.9 +2.1 2095 5.4 HDGF ARID4B ZNF48 GLIS2 ZNF143 KLF7 ZNF263 SP3 SP5 NCOA1 C10orf91 JAKMIP3 LOC105378569
GH10F132225 0.5 Ensembl 11.5 -218.0 -218027 1.0 KLF1 STK32C C10orf91 LOC105378568 DPYSL4 LOC105378567 GC10M132318
GH10F132334 0.2 ENCODE 11.5 -108.1 -108072 3.0 HDGF ATF1 PKNOX1 FEZF1 DMAP1 ZNF2 ZNF121 GLIS2 ZNF143 FOS LRRC27 STK32C C10orf91 LOC105378568 PWWP2B GC10P132333
GH10F132229 1.2 FANTOM5 Ensembl ENCODE 11.5 -212.5 -212483 4.9 CTCF SMARCA4 POLR2A NRF1 SP2 MAX FOXP2 STK32C C10orf91 LOC105378568 LRRC27 JAKMIP3 LOC105378567 GC10M132318
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C10orf91 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf91 Gene

132,444,327 bp from pter
132,449,408 bp from pter
5,082 bases
Plus strand

Genomic View for C10orf91 Gene

Genes around C10orf91 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf91 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf91 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf91 Gene

Proteins for C10orf91 Gene

  • Protein details for C10orf91 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C10orf91
    Protein Accession:
    Secondary Accessions:
    • Q8N0T7

    Protein attributes for C10orf91 Gene

    145 amino acids
    Molecular mass:
    15403 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf91 Gene

Post-translational modifications for C10orf91 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf91 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C10orf91 Gene

Domains & Families for C10orf91 Gene

Protein Domains for C10orf91 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf91: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf91 Gene

Function for C10orf91 Gene

Phenotypes for C10orf91 Gene

genes like me logo Genes that share phenotypes with C10orf91: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf91 Gene

Localization for C10orf91 Gene

Subcellular locations from

Jensen Localization Image for C10orf91 Gene COMPARTMENTS Subcellular localization image for C10orf91 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf91 Gene

Pathways & Interactions for C10orf91 Gene

SuperPathways for C10orf91 Gene

No Data Available

Interacting Proteins for C10orf91 Gene

Gene Ontology (GO) - Biological Process for C10orf91 Gene


No data available for Pathways by source and SIGNOR curated interactions for C10orf91 Gene

Transcripts for C10orf91 Gene

mRNA/cDNA for C10orf91 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf91 Gene

Chromosome 10 open reading frame 91:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf91 Gene

No ASD Table

Relevant External Links for C10orf91 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf91 Gene

mRNA expression in normal human tissues for C10orf91 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf91 Gene

This gene is overexpressed in Esophagus - Mucosa (x7.0), Bladder (x6.5), and Skin - Not Sun Exposed (Suprapubic) (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of C10orf91 Gene:


SOURCE GeneReport for Unigene cluster for C10orf91 Gene:

genes like me logo Genes that share expression patterns with C10orf91: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C10orf91 Gene

Orthologs for C10orf91 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C10orf91 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C10orf91 35
  • 95 (a)
Species where no ortholog for C10orf91 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf91 Gene

Gene Tree for C10orf91 (if available)
Gene Tree for C10orf91 (if available)

Paralogs for C10orf91 Gene

No data available for Paralogs for C10orf91 Gene

Variants for C10orf91 Gene

Sequence variations from dbSNP and Humsavar for C10orf91 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11146376 -- 132,448,054(+) CTTCG(A/G)AGCCT reference, missense
rs11146377 -- 132,448,233(+) GCAGA(G/T)GGCAG utr-variant-3-prime
rs11146378 -- 132,448,306(+) GGCTG(A/G)AACAC utr-variant-3-prime
rs111701171 -- 132,445,916(+) TGCCA(A/G)GAGGT intron-variant
rs111726693 -- 132,448,568(+) ACCCG(C/T)CCACC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for C10orf91 Gene

Variant ID Type Subtype PubMed ID
dgv121n27 CNV loss 19166990
dgv1458n54 CNV loss 21841781
esv2759791 CNV loss 17122850
esv3624986 CNV gain 21293372
nsv1054934 CNV gain 25217958
nsv1143659 CNV deletion 24896259
nsv470976 CNV loss 18288195
nsv552518 CNV loss 21841781
nsv832031 CNV loss 17160897
nsv951890 CNV deletion 24416366

Variation tolerance for C10orf91 Gene

Residual Variation Intolerance Score: 51.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf91 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf91 Gene

Disorders for C10orf91 Gene

Relevant External Links for C10orf91

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C10orf91 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf91 Gene

Publications for C10orf91 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A. … Kocher T. (J. Clin. Periodontol. 2013) 3 64
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64

Products for C10orf91 Gene

Sources for C10orf91 Gene

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