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Aliases for C10orf88 Gene

Aliases for C10orf88 Gene

  • Chromosome 10 Open Reading Frame 88 2 3 5

External Ids for C10orf88 Gene

Previous GeneCards Identifiers for C10orf88 Gene

  • GC10M124230
  • GC10M124681
  • GC10M118307

Summaries for C10orf88 Gene

GeneCards Summary for C10orf88 Gene

C10orf88 (Chromosome 10 Open Reading Frame 88) is a Protein Coding gene. GO annotations related to this gene include identical protein binding.

Additional gene information for C10orf88 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf88 Gene

Genomics for C10orf88 Gene

Regulatory Elements for C10orf88 Gene

Enhancers for C10orf88 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H122953 1.1 ENCODE 25.8 +0.2 249 1.6 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 C10orf88 IKZF5 BUB3 PSTK FAM24A
GH10H122849 1.3 Ensembl ENCODE dbSUPER 20.8 +100.9 100857 7.7 JUN INSM2 ZIC2 ZFHX2 ZNF316 POLR2A SCRT2 FOS ZNF600 NFE2 C10orf88 LOC399815 FAM24B IKZF5 ACADSB CUZD1
GH10H122860 1.4 Ensembl ENCODE dbSUPER 10.6 +91.2 91223 5.1 HDAC1 PKNOX1 FOXA2 THRB ZEB1 RARA TCF12 ZNF366 RCOR1 FOS C10orf88 ACADSB CUZD1 LOC399815
GH10H122284 0.9 ENCODE dbSUPER 15.8 +667.7 667724 4.5 ZIC2 ZKSCAN1 ZNF23 JUND RAD51 GLIS2 POLR2A ZNF341 PATZ1 ZNF600 BTBD16 C10orf88 HTRA1 GC10P122346
GH10H122331 1.1 ENCODE dbSUPER 10.6 +622.8 622774 0.8 TBP FOXA2 ARID4B DMAP1 RAD21 DNMT3B RARA SLC30A9 CREM MIXL1 IKZF5 BUB3 FAM24B C10orf88 ARMS2 GC10P122346 BTBD16
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C10orf88 on UCSC Golden Path with GeneCards custom track

Promoters for C10orf88 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for C10orf88 Gene

Genomic Locations for C10orf88 Gene
23,501 bases
Minus strand

Genomic View for C10orf88 Gene

Genes around C10orf88 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf88 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf88 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf88 Gene

Proteins for C10orf88 Gene

  • Protein details for C10orf88 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C10orf88
    Protein Accession:
    Secondary Accessions:
    • Q0P6C6
    • Q8N597

    Protein attributes for C10orf88 Gene

    445 amino acids
    Molecular mass:
    49249 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf88 Gene

Post-translational modifications for C10orf88 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf88 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf88 Gene

Domains & Families for C10orf88 Gene

Gene Families for C10orf88 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for C10orf88 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf88: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf88 Gene

Function for C10orf88 Gene

Phenotypes From GWAS Catalog for C10orf88 Gene

Gene Ontology (GO) - Molecular Function for C10orf88 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with C10orf88: view
genes like me logo Genes that share phenotypes with C10orf88: view

miRNA for C10orf88 Gene

miRTarBase miRNAs that target C10orf88

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf88 Gene

Localization for C10orf88 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf88 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
mitochondrion 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C10orf88 Gene

Pathways & Interactions for C10orf88 Gene

SuperPathways for C10orf88 Gene

No Data Available

Interacting Proteins for C10orf88 Gene

Gene Ontology (GO) - Biological Process for C10orf88 Gene


No data available for Pathways by source and SIGNOR curated interactions for C10orf88 Gene

Drugs & Compounds for C10orf88 Gene

No Compound Related Data Available

Transcripts for C10orf88 Gene

mRNA/cDNA for C10orf88 Gene

Unigene Clusters for C10orf88 Gene

Chromosome 10 open reading frame 88:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf88 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
SP1: -
SP2: -
SP3: - -
SP4: -

Relevant External Links for C10orf88 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf88 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf88 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for C10orf88 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C10orf88 Gene

Protein tissue co-expression partners for C10orf88 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C10orf88 Gene:


SOURCE GeneReport for Unigene cluster for C10orf88 Gene:

genes like me logo Genes that share expression patterns with C10orf88: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf88 Gene

Orthologs for C10orf88 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C10orf88 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C10H10orf88 33
  • 99.1 (n)
C10orf88 34
  • 98 (a)
(Bos Taurus)
Mammalia C26H10orf88 33
  • 82.16 (n)
-- 34
  • 75 (a)
-- 34
  • 74 (a)
(Canis familiaris)
Mammalia C28H10orf88 33
  • 80.22 (n)
-- 34
  • 73 (a)
-- 34
  • 72 (a)
(Rattus norvegicus)
Mammalia RGD1305014 33
  • 79.88 (n)
(Mus musculus)
Mammalia 2310057M21Rik 33 16 34
  • 78.9 (n)
(Monodelphis domestica)
Mammalia C10orf88 34
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia C10orf88 34
  • 59 (a)
(Gallus gallus)
Aves C6H10ORF88 33
  • 59.81 (n)
C10orf88 34
  • 45 (a)
(Anolis carolinensis)
Reptilia C10orf88 34
  • 40 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485309 33
  • 48.94 (n)
(Danio rerio)
Actinopterygii si:rp71-19m20.1 33
  • 48.16 (n)
C12H10orf88 34
  • 30 (a)
Species where no ortholog for C10orf88 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C10orf88 Gene

Gene Tree for C10orf88 (if available)
Gene Tree for C10orf88 (if available)

Paralogs for C10orf88 Gene Pseudogenes for C10orf88 Gene

genes like me logo Genes that share paralogs with C10orf88: view

No data available for Paralogs for C10orf88 Gene

Variants for C10orf88 Gene

Sequence variations from dbSNP and Humsavar for C10orf88 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000088044 -- 122,955,591(+) CATAG(A/C)AGAAT upstream-variant-2KB
rs1000152254 -- 122,946,476(+) TGCAA(A/G)TACAT intron-variant
rs1000205165 -- 122,946,135(+) GCTTA(A/G)TTTAT intron-variant
rs1000323626 -- 122,951,562(+) AATTT(-/A)AAAAA intron-variant
rs1000515615 -- 122,932,112(+) TTAAA(C/T)ACATA downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C10orf88 Gene

Variant ID Type Subtype PubMed ID
nsv832010 CNV gain 17160897
esv6242 OTHER inversion 19470904

Variation tolerance for C10orf88 Gene

Residual Variation Intolerance Score: 84.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.00; 36.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf88 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf88 Gene

Disorders for C10orf88 Gene

Relevant External Links for C10orf88

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C10orf88 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf88 Gene

Publications for C10orf88 Gene

  1. Association of vitamin D-related gene polymorphisms with manifestation of vitamin D deficiency in children. (PMID: 22785457) Kitanaka S … Igarashi T (Endocrine journal 2012) 2 3 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for C10orf88 Gene

Sources for C10orf88 Gene

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