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Aliases for C10orf71 Gene

Aliases for C10orf71 Gene

  • Chromosome 10 Open Reading Frame 71 2 3 5

External Ids for C10orf71 Gene

Previous GeneCards Identifiers for C10orf71 Gene

  • GC10P049851
  • GC10P050177
  • GC10P050507
  • GC10P044771

Summaries for C10orf71 Gene

GeneCards Summary for C10orf71 Gene

C10orf71 (Chromosome 10 Open Reading Frame 71) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf71 Gene

Genomics for C10orf71 Gene

Regulatory Elements for C10orf71 Gene

Enhancers for C10orf71 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F049270 1.6 FANTOM5 Ensembl ENCODE 16.9 -24.6 -24638 3.2 NR2F2 C10orf71 C10orf71-AS1 C10orf128 DRGX GC10P049274
GH10F049318 0.3 FANTOM5 11.9 +21.6 21578 0.2 C10orf128 C10orf71 ENSG00000235939 C10orf71-AS1 GC10M049333
GH10F049319 0.4 Ensembl 11.9 +21.8 21845 0.2 C10orf71 C10orf128 ENSG00000235939 C10orf71-AS1 GC10M049333
GH10F049335 0.5 ENCODE 10.4 +38.5 38533 0.9 HDGF HDAC1 BCOR ESRRA CBX3 ZMYM3 ZBTB40 CHAMP1 ZNF664 NR2F2 DRGX C10orf71 C10orf71-AS1 PGBD3 GC10M049333
GH10F049205 1.2 VISTA 10.4 -91.2 -91225 0.9 ZNF121 GLIS1 HMBOX1 MLLT1 KDM1A DRGX C10orf71 C10orf71-AS1 C10orf128 GC10P049274
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C10orf71 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf71 Gene

Chromosome:
10
Start:
49,297,056 bp from pter
End:
49,327,492 bp from pter
Size:
30,437 bases
Orientation:
Plus strand

Genomic View for C10orf71 Gene

Genes around C10orf71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf71 Gene

Proteins for C10orf71 Gene

  • Protein details for C10orf71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q711Q0-CJ071_HUMAN
    Recommended name:
    Uncharacterized protein C10orf71
    Protein Accession:
    Q711Q0
    Secondary Accessions:
    • A0AVL8

    Protein attributes for C10orf71 Gene

    Size:
    1435 amino acids
    Molecular mass:
    156477 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAC85340.1; Type=Frameshift; Positions=1282, 1418; Evidence={ECO:0000305};

    Alternative splice isoforms for C10orf71 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C10orf71 Gene

Post-translational modifications for C10orf71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf71 Gene

No data available for DME Specific Peptides for C10orf71 Gene

Domains & Families for C10orf71 Gene

Protein Domains for C10orf71 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf71: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf71 Gene

Function for C10orf71 Gene

genes like me logo Genes that share phenotypes with C10orf71: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf71 Gene

Localization for C10orf71 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C10orf71 Gene COMPARTMENTS Subcellular localization image for C10orf71 gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf71 Gene

Pathways & Interactions for C10orf71 Gene

SuperPathways for C10orf71 Gene

No Data Available

Interacting Proteins for C10orf71 Gene

Gene Ontology (GO) - Biological Process for C10orf71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf71 Gene

Transcripts for C10orf71 Gene

mRNA/cDNA for C10orf71 Gene

Unigene Clusters for C10orf71 Gene

Chromosome 10 open reading frame 71:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf71 Gene

No ASD Table

Relevant External Links for C10orf71 Gene

GeneLoc Exon Structure for
C10orf71
ECgene alternative splicing isoforms for
C10orf71

Expression for C10orf71 Gene

mRNA expression in normal human tissues for C10orf71 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf71 Gene

This gene is overexpressed in Muscle - Skeletal (x35.1), Heart - Left Ventricle (x12.2), and Heart - Atrial Appendage (x4.2).

Protein differential expression in normal tissues from HIPED for C10orf71 Gene

This gene is overexpressed in Liver, secretome (49.5) and Breast (17.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf71 Gene



Protein tissue co-expression partners for C10orf71 Gene

NURSA nuclear receptor signaling pathways regulating expression of C10orf71 Gene:

C10orf71

SOURCE GeneReport for Unigene cluster for C10orf71 Gene:

Hs.585480
genes like me logo Genes that share expression patterns with C10orf71: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C10orf71 Gene

Orthologs for C10orf71 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C10orf71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf71 34
  • 98.94 (n)
C10orf71 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C28H10orf71 34
  • 80.72 (n)
C10orf71 35
  • 73 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C28H10orf71 34
  • 79.52 (n)
C10orf71 35
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564899 34
  • 75.8 (n)
mouse
(Mus musculus)
Mammalia 3425401B19Rik 34 16 35
  • 75.39 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 51 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia C10orf71 35
  • 47 (a)
OneToOne
chicken
(Gallus gallus)
Aves C6H10ORF71 34
  • 50.37 (n)
C10orf71 35
  • 30 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C10orf71 35
  • 30 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C10orf71 (1 of 2) 35
  • 13 (a)
OneToMany
C10orf71 (2 of 2) 35
  • 10 (a)
OneToMany
Species where no ortholog for C10orf71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C10orf71 Gene

ENSEMBL:
Gene Tree for C10orf71 (if available)
TreeFam:
Gene Tree for C10orf71 (if available)

Paralogs for C10orf71 Gene

No data available for Paralogs for C10orf71 Gene

Variants for C10orf71 Gene

Sequence variations from dbSNP and Humsavar for C10orf71 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10661682 -- 49,310,776(+) AGCCA(-/GAT)GATGA intron-variant
rs10776558 -- 49,302,361(+) TCAGC(C/T)GAAGA intron-variant
rs10776559 -- 49,318,358(+) TCCCC(A/G)ACCCA intron-variant
rs10857462 -- 49,295,367(+) GAGAG(A/G)TCCTC upstream-variant-2KB
rs10857463 -- 49,302,025(+) TGAGG(A/G)GCTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C10orf71 Gene

Variant ID Type Subtype PubMed ID
esv2255118 CNV deletion 18987734
nsv1042677 CNV loss 25217958
nsv1122527 CNV deletion 24896259

Variation tolerance for C10orf71 Gene

Residual Variation Intolerance Score: 98.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 18.63; 98.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf71 Gene

Disorders for C10orf71 Gene

Relevant External Links for C10orf71

Genetic Association Database (GAD)
C10orf71
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf71

No disorders were found for C10orf71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf71 Gene

Publications for C10orf71 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  3. Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. (PMID: 24823311) Guan W. … Steffen L.M. (Circ Cardiovasc Genet 2014) 3 64
  4. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. (PMID: 23362303) Wu J.H. … Mozaffarian D. (Circ Cardiovasc Genet 2013) 3 64
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64

Products for C10orf71 Gene

Sources for C10orf71 Gene

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