C10orf67 Gene
protein-coding GIFtS: 38
GCID: GC10M023556
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chromosome 10 open reading frame 67
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Aliases
for C10orf67 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 10 Open Reading Frame 671 2 | | MGC467321 | | Uncharacterized Protein C10orf672 |
Export aliases for C10orf67 gene to outside databasesPrevious GC identifers: GC10M023609 GC10M023645 GC10M023265 |
Summaries
for C10orf67 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C10orf67 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C10orf67 gene promoter:
TBP AML1a POU6F1 (c2) E47 POU2F1 Nkx6-1 POU2F1a Hand1 Cart-1 Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for C10orf67
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf67 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p12.2 Ensembl cytogenetic band: 10p12.2 HGNC cytogenetic band: 10p12.31C10orf67 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M023556: view genomic region
(about GC identifiers)
Start:
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23,556,124 bp from pter |
End:
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23,633,774 bp from pter |
Size:
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77,651 bases |
Orientation:
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minus strand |
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Proteins
for C10orf67 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CJ067_HUMAN, Q8IYJ2 (See
protein sequence)Recommended Name: Uncharacterized protein C10orf67 Size: 185 amino acids; 21594 Da
Caution: It is uncertain whether Met-1 or Met-2 is the initiator
Sequence caution: Sequence=AAH35732.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8MUP9 Q5SWD4Explore the universe of human proteins at neXtProt for C10orf67: NX_Q8IYJ2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYJ2
C10orf67 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_714925.2
ENSEMBL proteins: ENSP00000365683 ENSP00000321464
Human Recombinant Protein Products:
C10orf67 Antibody Products:
Assay Products for C10orf67: |
Protein
Domains /
Families
for C10orf67 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8IYJ2 |
Function
for C10orf67 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: C10orf67 (NM_153714) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf67 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf67 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf67 |
|
Pathways & Interactions
for C10orf67 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C10orf67
|
Drugs & Compounds
for C10orf67 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C10orf67
Search CenterWatch for drugs/clinical trials and news about C10orf67 / CJ067
|
Transcripts
for C10orf67 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C10orf67 gene: NM_153714.2 Unigene Cluster for C10orf67: Chromosome 10 open reading frame 67 Hs.522360 [show with all ESTs]Unigene Representative Sequence: BC0357322 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000376500 ENST00000323327(uc010qcx.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: C10orf67 (NM_153714) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf67 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf67 |
Additional cDNA sequence: BC035732.1 3 DOTS entries: DT.97823306 DT.121220425 DT.70100540 6 AceView cDNA sequences: BM805554 AI301009 NM_153714 BC035732 CA944707 AW024692
GeneLoc Exon Structure
|
Expression
for C10orf67 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C10orf67 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACAGCAGCA
About this image
See C10orf67 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C10orf67
SOURCE GeneReport for Unigene cluster: Hs.522360
SABiosciences Custom PCR Arrays for C10orf67
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf67
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat C10orf67 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf67 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf67 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf67 |
Orthologs
for C10orf67 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for C10orf67 gene from 4/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
4921504E06Rik5 |
RIKEN cDNA 4921504E06 gene |
-- |
|
2 (13.40 cM) 19462837 |
chicken
(Gallus gallus) |
Aves |
C10orf676 |
Uncharacterized protein |
19(a) |
1 ↔ 1 |
2(17289860-17301786) |
lizard
(Anolis carolinensis) |
Reptilia |
C10orf676 |
-- |
33(a) |
1 ↔ 1 |
6(15889314-15892564) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkey-188g12.16 |
si:dkey-188g12.1 |
8(a) |
1 ↔ 1 |
2(29441590-29476797) |
ENSEMBL Gene Tree for C10orf67 (if available)
TreeFam Gene Tree for C10orf67 (if available) |
Paralogs
for C10orf67 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C10orf67 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C10orf67 (23556124 - 23633774 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C10orf67: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf67 |
|
Disorders
/ Diseases
for C10orf67 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C10orf67 for disorders About GeneDecksing
2  diseases for C10orf67: About MalaCardscrohn's disease sarcoidosis
Human Genome Epidemiology (HuGE) Navigator: C10orf67 (1 document)
Export disorders for C10orf67 gene to outside databases
|
Publications
for C10orf67 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C10orf67 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C10orf67) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2. (PubMed id 18723019)1 Franke A....Schreiber S. (2008)
|
External Searches for C10orf67 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf67 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C10orf67 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf67 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C10orf67 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C10orf67 gene:
Search GeneIP for patents involving C10orf67
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C10orf67 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C10orf67 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C10orf67 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf67 | | | OriGene Protein Over-expression Lysate for C10orf67 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C10orf67 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf67 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C10orf67 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf67 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf67 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C10orf67 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf67 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf67 |
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 | | | C10orf67 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf67 |
|  |  |  | | | | Search ThermoFisher Antibodies for C10orf67 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf67 |
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