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Aliases for C10orf62 Gene

Aliases for C10orf62 Gene

  • Chromosome 10 Open Reading Frame 62 2 3 5
  • Uncharacterized Protein C10orf62 3
  • BA548K23.1 3

External Ids for C10orf62 Gene

Previous GeneCards Identifiers for C10orf62 Gene

  • GC10U900455
  • GC10P099339
  • GC10P099349
  • GC10P092975

Summaries for C10orf62 Gene

GeneCards Summary for C10orf62 Gene

C10orf62 (Chromosome 10 Open Reading Frame 62) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf62 Gene

Genomics for C10orf62 Gene

Regulatory Elements for C10orf62 Gene

Enhancers for C10orf62 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G097195 1.7 FANTOM5 Ensembl ENCODE dbSUPER 59.7 -393.1 -393063 1.8 ARID4B ZNF76 RAD21 GLIS2 ZNF366 ZNF143 FOS EGR2 SP3 REST C10orf62 SLIT1 PIR51669
GH10G097537 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -48.3 -48346 6.8 PKNOX1 ZFP64 SIN3A ARID4B ZNF2 YY1 ZNF121 GLIS2 FOS ZNF263 PI4K2A ANKRD2 UBTD1 MMS19 ENSG00000249967 HOGA1 C10orf62 RRP12 GC10P097540
GH10G097517 1.2 Ensembl ENCODE dbSUPER 17.2 -71.2 -71156 2.6 CTCF JUN EBF1 RAD21 ZNF664 SMC3 FOSL2 FOS SP3 ZNF654 HOGA1 C10orf62 ENSG00000249967 PI4K2A ANKRD2 ZDHHC16 SLIT1 GC10P097506 GC10P097530
GH10G097405 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.1 -182.2 -182206 3.8 HDGF ATF1 MLX ZFP64 ARID4B SIN3A ZNF2 ZNF48 TCF12 ZNF143 FRAT2 RRP12 FRAT1 ARHGAP19 EXOSC1 ZDHHC16 UBTD1 MMS19 ENSG00000249967 HOGA1
GH10G097639 1.6 FANTOM5 ENCODE dbSUPER 10.9 +51.5 51474 2.7 HDGF PKNOX1 FOXA2 ARID4B SIN3A YY1 ZNF143 FOS KLF13 SP3 MORN4 ZFYVE27 ANKRD2 AVPI1 C10orf62 ENSG00000249967 HOGA1 UBTD1 MMS19 PI4K2A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C10orf62 on UCSC Golden Path with GeneCards custom track

Genomic Location for C10orf62 Gene

Chromosome:
10
Start:
97,589,693 bp from pter
End:
97,590,934 bp from pter
Size:
1,242 bases
Orientation:
Plus strand

Genomic View for C10orf62 Gene

Genes around C10orf62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C10orf62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C10orf62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf62 Gene

Proteins for C10orf62 Gene

  • Protein details for C10orf62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T681-CJ062_HUMAN
    Recommended name:
    Uncharacterized protein C10orf62
    Protein Accession:
    Q5T681
    Secondary Accessions:
    • Q49A70
    • Q8N3Y6

    Protein attributes for C10orf62 Gene

    Size:
    223 amino acids
    Molecular mass:
    25128 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C10orf62 Gene

Post-translational modifications for C10orf62 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf62 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf62 Gene

Domains & Families for C10orf62 Gene

Protein Domains for C10orf62 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf62: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf62 Gene

Function for C10orf62 Gene

Gene Ontology (GO) - Molecular Function for C10orf62 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with C10orf62: view

Phenotypes for C10orf62 Gene

GenomeRNAi human phenotypes for C10orf62:
genes like me logo Genes that share phenotypes with C10orf62: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C10orf62 Gene

Localization for C10orf62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C10orf62 gene
Compartment Confidence
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf62 Gene

Pathways & Interactions for C10orf62 Gene

SuperPathways for C10orf62 Gene

No Data Available

Gene Ontology (GO) - Biological Process for C10orf62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf62 Gene

Drugs & Compounds for C10orf62 Gene

No Compound Related Data Available

Transcripts for C10orf62 Gene

mRNA/cDNA for C10orf62 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C10orf62 Gene

Chromosome 10 open reading frame 62:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf62 Gene

No ASD Table

Relevant External Links for C10orf62 Gene

GeneLoc Exon Structure for
C10orf62
ECgene alternative splicing isoforms for
C10orf62

Expression for C10orf62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C10orf62 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf62 Gene

This gene is overexpressed in Testis (x51.2).

Protein differential expression in normal tissues from HIPED for C10orf62 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C10orf62 Gene



Protein tissue co-expression partners for C10orf62 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of C10orf62 Gene:

C10orf62

SOURCE GeneReport for Unigene cluster for C10orf62 Gene:

Hs.662302
genes like me logo Genes that share expression patterns with C10orf62: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C10orf62 Gene

Orthologs for C10orf62 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C10orf62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf62 34
  • 98.95 (n)
dog
(Canis familiaris)
Mammalia C28H10orf62 34
  • 78.84 (n)
C10orf62 35
  • 68 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C26H10orf62 34
  • 77.78 (n)
rat
(Rattus norvegicus)
Mammalia MGC93861 34
  • 70.27 (n)
mouse
(Mus musculus)
Mammalia 4933411K16Rik 34 16 35
  • 70.1 (n)
oppossum
(Monodelphis domestica)
Mammalia C10orf62 35
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C10orf62 35
  • 41 (a)
OneToOne
Species where no ortholog for C10orf62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf62 Gene

ENSEMBL:
Gene Tree for C10orf62 (if available)
TreeFam:
Gene Tree for C10orf62 (if available)

Paralogs for C10orf62 Gene

No data available for Paralogs for C10orf62 Gene

Variants for C10orf62 Gene

Sequence variations from dbSNP and Humsavar for C10orf62 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000194610 -- 97,591,148(+) TCTGA(A/T)GTTGC intron-variant
rs1002456222 -- 97,588,546(+) GAGAC(C/T)AGAGG intron-variant, upstream-variant-2KB
rs1003075808 -- 97,588,983(+) GCCAG(-/C)CCCAC intron-variant, upstream-variant-2KB
rs1005180264 -- 97,590,869(+) TGGGA(G/T)CAGGC intron-variant, utr-variant-3-prime
rs1005276865 -- 97,590,641(+) CACAC(A/G)CACGT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C10orf62 Gene

Variant ID Type Subtype PubMed ID
nsv1047359 CNV gain 25217958
nsv1110852 OTHER inversion 24896259
nsv818782 CNV loss 17921354

Variation tolerance for C10orf62 Gene

Residual Variation Intolerance Score: 89.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.51; 82.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C10orf62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf62 Gene

Disorders for C10orf62 Gene

Relevant External Links for C10orf62

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf62

No disorders were found for C10orf62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C10orf62 Gene

Publications for C10orf62 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3 64
  5. Shifted Transversal Design smart-pooling for high coverage interactome mapping. (PMID: 19447967) Xin X. … Thierry-Mieg N. (Genome Res. 2009) 3 64

Products for C10orf62 Gene

Sources for C10orf62 Gene

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