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Aliases for C10orf53 Gene

Aliases for C10orf53 Gene

  • Chromosome 10 Open Reading Frame 53 2 3

External Ids for C10orf53 Gene

Previous GeneCards Identifiers for C10orf53 Gene

  • GC10P050233
  • GC10P050557
  • GC10P050887
  • GC10P045152

Summaries for C10orf53 Gene

GeneCards Summary for C10orf53 Gene

C10orf53 (Chromosome 10 Open Reading Frame 53) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf53 Gene

Genomics for C10orf53 Gene

Regulatory Elements for C10orf53 Gene

Genomic Location for C10orf53 Gene

49,679,638 bp from pter
49,710,261 bp from pter
30,624 bases
Plus strand

Genomic View for C10orf53 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C10orf53 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf53 Gene

Proteins for C10orf53 Gene

  • Protein details for C10orf53 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    UPF0728 protein C10orf53
    Protein Accession:
    Secondary Accessions:
    • A6NI81
    • A6NLE0
    • B9ZVK6

    Protein attributes for C10orf53 Gene

    93 amino acids
    Molecular mass:
    10399 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C10orf53 Gene


neXtProt entry for C10orf53 Gene

Proteomics data for C10orf53 Gene at MOPED

Post-translational modifications for C10orf53 Gene

No Post-translational modifications

Other Protein References for C10orf53 Gene

No data available for DME Specific Peptides for C10orf53 Gene

Domains for C10orf53 Gene

Protein Domains for C10orf53 Gene


Suggested Antigen Peptide Sequences for C10orf53 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UPF0728 family.
  • Belongs to the UPF0728 family.
genes like me logo Genes that share domains with C10orf53: view

No data available for Gene Families for C10orf53 Gene

Function for C10orf53 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C10orf53

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C10orf53 Gene

Localization for C10orf53 Gene

Subcellular locations from

Jensen Localization Image for C10orf53 Gene COMPARTMENTS Subcellular localization image for C10orf53 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C10orf53 Gene

Pathways for C10orf53 Gene

SuperPathways for C10orf53 Gene

No Data Available

Interacting Proteins for C10orf53 Gene

Gene Ontology (GO) - Biological Process for C10orf53 Gene


No data available for Pathways by source for C10orf53 Gene

Transcripts for C10orf53 Gene

mRNA/cDNA for C10orf53 Gene

Unigene Clusters for C10orf53 Gene

Chromosome 10 open reading frame 53:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C10orf53

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf53 Gene

No ASD Table

Relevant External Links for C10orf53 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C10orf53 Gene

mRNA expression in normal human tissues for C10orf53 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf53 Gene

This gene is overexpressed in Testis (47.0).

Protein differential expression in normal tissues for C10orf53 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C10orf53 Gene

SOURCE GeneReport for Unigene cluster for C10orf53 Gene Hs.131287

genes like me logo Genes that share expressions with C10orf53: view

Expression partners for C10orf53 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C10orf53 Gene

Orthologs for C10orf53 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C10orf53 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C28H10orf53 35
  • 84.23 (n)
  • 81.72 (a)
C28H10orf53 36
  • 67 (a)
(Canis familiaris)
Mammalia C28H10orf53 35
  • 87.1 (n)
  • 89.25 (a)
C10orf53 36
  • 73 (a)
(Mus musculus)
Mammalia 1700024G13Rik 35
  • 80.29 (n)
  • 77.42 (a)
1700024G13Rik 16
1700024G13Rik 36
  • 63 (a)
(Rattus norvegicus)
Mammalia LOC680885 35
  • 79.93 (n)
  • 78.49 (a)
(Monodelphis domestica)
Mammalia C10orf53 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia C10orf53 36
  • 57 (a)
(Pan troglodytes)
Mammalia C10orf53 36
  • 96 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485377 35
  • 64.52 (n)
  • 64.52 (a)
(Danio rerio)
Actinopterygii zgc:153142 35
  • 60.51 (n)
  • 61.96 (a)
C13H10orf53 36
  • 50 (a)
Species with no ortholog for C10orf53:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C10orf53 Gene

Gene Tree for C10orf53 (if available)
Gene Tree for C10orf53 (if available)

Paralogs for C10orf53 Gene

No data available for Paralogs for C10orf53 Gene

Variants for C10orf53 Gene

Sequence variations from dbSNP and Humsavar for C10orf53 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1025740 -- 49,689,818(+) ATTTT(A/T)AAAAT intron-variant
rs1025741 -- 49,690,141(+) CACAA(A/T)AGGGG intron-variant
rs1025742 -- 49,690,313(+) TCACC(G/T)CAGCA intron-variant
rs1055421 -- 49,694,638(+) CACAA(C/T)AGCAG utr-variant-3-prime, intron-variant
rs1133837 -- 49,693,892(+) GAGTT(C/T)GGTAA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for C10orf53 Gene

Variant ID Type Subtype PubMed ID
nsv7203 OTHER Inversion 18451855
nsv895365 CNV Loss 21882294
nsv895375 CNV Gain 21882294
nsv895378 CNV Gain 21882294

Relevant External Links for C10orf53 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf53 Gene

Disorders for C10orf53 Gene

Relevant External Links for C10orf53

Human Genome Epidemiology (HuGE) Navigator

No disorders were found for C10orf53 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for C10orf53 Gene

Publications for C10orf53 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for C10orf53 Gene

Sources for C10orf53 Gene

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