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Aliases &
Descriptions
for C10orf53
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| Em:AC069546.1 1 | | OTTHUMP00000019586 2 | | OTTHUMP00000019587 2 |
| | | Descriptions |
|---|
| chromosome 10 open reading frame 53 2 |
|
| |
Search outside databases for aliases for C10orf53 genePrevious GC identifer: GC10P050233 |
Summaries
for C10orf53(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location
for C10orf53
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the C10orf53 gene 
Entrez Gene cytogenetic band: 10q11.23 Ensembl cytogenetic band: 10q11.23 HGNC chromosome: 10C10orf53 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P050557:
(about GC identifiers)
Start:
|
50,557,690 bp from pter |
End:
|
50,586,962 bp from pter |
Size:
|
29,273 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000010.9 NT_017696.14
| Proteins
for C10orf53
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: CJ053_HUMAN, Q8N6V4 (See
protein sequence)Recommended Name: UPF0728 protein C10orf53 Size: 93 amino acids; 10399 Da
Secondary accessions: A6NI81 A6NLE0Alternative splicing: 3 isoforms: Q8N6V4-1 Q8N6V4-2 Q8N6V4-3 Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins (2 alternative transcripts):
NP_001035892.1 NP_872360.2
ENSEMBL proteins: ENSP00000363225 ENSP00000363227 ENSP00000363226
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
Antibodies for C10orf53:
Assays for C10orf53: | Protein
Domains/
Families
for C10orf53(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8N6V4 UniProtKB/Swiss-Prot: CJ053_HUMAN, Q8N6V4Similarity: Belongs to the UPF0728 family | Gene Function
for C10orf53
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001042427
 Applied Biosystems Silencer® siRNAs for C10orf53
 Sigma-Aldrich siRNA for C10orf53
Sigma-Aldrich shRNA for C10orf53
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001042427
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001042427
untagged cDNA clones in CMV expression vector (see all 2): NM_001042427
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_182554
| Pathways & Interactions
for C10orf53
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
-- |
Drugs & Compounds
for C10orf53(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for C10orf53
|
Transcripts
for C10orf53(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001042427
Sigma-Aldrich siRNA for C10orf53
Sigma-Aldrich shRNA for C10orf53
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001042427 NM_182554 REFSEQ mRNAs for C10orf53 gene (2 alternative transcripts): NM_001042427.1 NM_182554.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001042427 NM_182554
OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001042427
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001042427
untagged cDNA clones in CMV expression vector (see all 2): NM_001042427
Additional cDNA sequence: AK091773.1 3 DOTS entries: DT.456121 DT.99931099 DT.95203350 24/32 AceView cDNA sequences (see all 32
):D82342 BX102324 AF305909 BX280506 NM_020549 NM_182554 S45018 AX747176 AI216456 BV183664 AK091773 D82339 BC028127 BI826396 AI990484 NM_020986 NM_020985 D82340 NM_020984 D82341 AF305907 AI917746 S56138 BI825648
 highest scoring ESTs for C10orf53:BI825648 BC028127 CV030399 NM_182554 AI990484 AK091773 DA583066 DB043416 DB319280 H88923 Unigene Cluster for C10orf53: Chromosome 10 open reading frame 53 Hs.131287 [show with all ESTs]Unigene Representative Sequence: AK091773
GeneLoc Exon Structure
3 Ensembl transcripts including schematic representations: ENST00000374111
ENST00000374113
ENST00000374112
|
Expression
for C10orf53
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| C10orf53 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for C10orf53
1 / 2 / 3 4 probe-sets matching C10orf53 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TCTCAATCTC
SOURCE GeneReport for Unigene cluster: Hs.131287
|
Orthologs
for C10orf53
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for C10orf53 gene from 2 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
LOC7370101 |
-- |
chromosome 10 open reading frame 53 |
98.73(n)
96.18(a) |
737010 XM_001139403.1 XP_001139403.1 |
mouse
(Mus musculus) |
1700024G13Rik5 |
14 |
RIKEN cDNA 1700024G13 gene |
-- |
BC107223 |
About this table Species with no ortholog for C10orf53
ENSEMBL Gene Tree for C10orf53 | Paralogs
for C10orf53(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
SNPs/Variants
for C10orf53(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for C10orf53 (up to first 250kb)
|
Disorders & Mutations
for C10orf53
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for C10orf53(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for C10orf53 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 5 PubMed articles for C10orf53 gene: |
Search for C10orf53
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf53
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing C10orf53
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf53(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for C10orf53(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for C10orf53:
|
GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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