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C10orf40 Gene

RNA gene   GIFtS: 28

GC10M061387
chromosome 10 open reading frame 40
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
AC023904.2 1
Descriptions
chromosome 10 open reading frame 40 2
External Ids
HGNC: 235241
Entrez Gene: 2830252
UniProtKB: A4QN013
Search outside databases for aliases for C10orf40 gene

Previous GC identifers: GC10M061062 GC10U900730

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:
UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.2   HGNC cytogenetic band: 10q21.3

C10orf40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M061387:     (about GC identifiers)

Start:
61,387,982 bp from pter
End:
61,389,733 bp from pter
Size:
1,752 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000010.9  NT_008583.16  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CJ040_HUMAN, A4QN01 (See protein sequence)
Recommended Name: Putative uncharacterized protein C10orf40  
Size: 128 amino acids; 15288 Da
Secondary accessions: A6NCD0

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2



  • Human Recombinant Proteins 
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    Antibodies for C10orf40: 
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    Assays for C10orf40: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: A4QN01

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (C10orf40)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                    Browse Origene for 29mer shRNA kit in GFP-retroviral vector

                  Browse siRNA at Sigma-Aldrich  
                         Browse shRNA at Sigma-Aldrich  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                    Browse Origene for untagged/tagged cDNA clones in CMV expression vector

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                    Browse Origene genome-wide validated SYBR primer pairs

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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      --
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for C10orf40

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (C10orf40)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                    Browse Origene for 29mer shRNA kit in GFP-retroviral vector

                  Browse siRNA at Sigma-Aldrich  
                         Browse shRNA at Sigma-Aldrich  
                         Explore Sigma-Aldrich super-pooled esiRNAs  


                    Browse Origene for untagged/tagged cDNA clones in CMV expression vector

    Additional cDNA sequence: 

    BC038741.1 BC048976.2 BC119749.2 BC119750.2 BC126326.1 BC130402.1 CR933684.1 

    2 DOTS entries:

    DT.204440  DT.101957393 

    10 AceView cDNA sequences:

    BX105262 BI463999 AA776736 BC048976 BG723969 AI252778 BC038741 BX642984 
    AA436670 BG724062 

    highest scoring ESTs for C10orf40:

    AA776736 BC038741 AA436670 BC048976 BG723969 BI463999 BX105262 CR933684 H52865 AI252778 

    Unigene Cluster for C10orf40:

    Chromosome 10 open reading frame 40
    Hs.522955  [show with all ESTs]
    Unigene Representative Sequence: CR933684


    GeneLoc Exon Structure

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    C10orf40 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for C10orf40

    1 / 2 / 3

    2 probe-sets matching C10orf40 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    56699_at2, 3 U95-B 1 1.00 1.00 1.00 1.00 AA776736 0.80 1.00 0.91 1

    1556648_a_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GCCTAATTCC

    SOURCE GeneReport for Unigene cluster: Hs.522955
    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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      --
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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      --
    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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    10/39 NCBI SNPs in C10orf40 are shown (see all 39 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 44)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 10 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs38512501,2
    A,C,F,H61389940(+) CTCATT/ATCCTT 1 -- ng314Minor allele frequency- A:0.50EU EA WA 410
    rs20536611,2
    A,C,F,H61391524(+) TGAAGG/TAAAGA 1 -- ng318Minor allele frequency- T:0.50EU EA WA 832
    --
    rs108216191,2
    A,C,F,H61391122(+) CAATAT/CTTGTT 1 -- ng314Minor allele frequency- C:0.46EU EA WA 392
    rs24504551,2
    C,F,H,O61391365(-) AGGCAA/TTGTGT 1 -- ng317Minor allele frequency- T:0.45EU EA WA NA 558
    rs108216181,2
    A,F,H61391089(+) TTACAT/CTCTCA 1 -- ng314Minor allele frequency- C:0.50EU EA WA 392
    rs24504541,2
    C,F,H61391543(-) CAAACA/GTAAtt 1 -- ng318Minor allele frequency- G:0.02EU EA WA 840
    --
    rs109940911,2
    A,C,F61389165(+) CTTTTC/TGCAAA 1 -- ut514Minor allele frequency- T:0.44EA NA 214
    rs71008391,2
    A,C,H61388375(+) AAACCG/ATCTAA 1 W/R mis14Minor allele frequency- A:0.00EU EA WA 418
    rs127762621,2
    C,F,H61389391(+) GTGTGT/GCCTCA 1 -- ut514Minor allele frequency- G:0.30EU EA WA 408
    --
    rs38432411,2
    A,C61390390(+) tgacaC/Tataat 1 -- ng310--------
    About this table

    HapMap Linkage Disequilibrium images for C10orf40 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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      --

    (Possibly Related Articles in Doctor's Guide)
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      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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    3 PubMed articles for C10orf40 gene:
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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    Entrez Gene: 283025 HGNC: 23524 AceView: C10orf40 euGenes: HUgn283025 ECgene: C10orf40
    H-InvDB: C10orf40
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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      --
    (Available from WIS Yeda, Salk, Tufts)
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      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for C10orf40:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



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     Millipore Target Screening & Profiling Services


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