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Aliases for C10orf35 Gene

Aliases for C10orf35 Gene

  • Chromosome 10 Open Reading Frame 35 2 3

External Ids for C10orf35 Gene

Previous GeneCards Identifiers for C10orf35 Gene

  • GC10P070734
  • GC10P071060
  • GC10P071390
  • GC10P065379

Summaries for C10orf35 Gene

GeneCards Summary for C10orf35 Gene

C10orf35 (Chromosome 10 Open Reading Frame 35) is a Protein Coding gene. Diseases associated with C10orf35 include uterine benign neoplasm.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C10orf35 Gene

Genomics for C10orf35 Gene

Regulatory Elements for C10orf35 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C10orf35 Gene

Chromosome:
10
Start:
69,630,243 bp from pter
End:
69,633,599 bp from pter
Size:
3,357 bases
Orientation:
Plus strand

Genomic View for C10orf35 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C10orf35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C10orf35 Gene

Proteins for C10orf35 Gene

  • Protein details for C10orf35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96D05-CJ035_HUMAN
    Recommended name:
    Uncharacterized protein C10orf35
    Protein Accession:
    Q96D05

    Protein attributes for C10orf35 Gene

    Size:
    121 amino acids
    Molecular mass:
    13238 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C10orf35 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C10orf35 Gene

Proteomics data for C10orf35 Gene at MOPED

Post-translational modifications for C10orf35 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C10orf35 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C10orf35 Gene

Domains & Families for C10orf35 Gene

Protein Domains for C10orf35 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C10orf35: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C10orf35 Gene

Function for C10orf35 Gene

Gene Ontology (GO) - Molecular Function for C10orf35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with C10orf35: view
genes like me logo Genes that share phenotypes with C10orf35: view

Animal Model Products

CRISPR Products

miRNA for C10orf35 Gene

miRTarBase miRNAs that target C10orf35

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C10orf35

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for C10orf35 Gene

Localization for C10orf35 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C10orf35 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for C10orf35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C10orf35: view

No data available for Subcellular locations from COMPARTMENTS for C10orf35 Gene

Pathways & Interactions for C10orf35 Gene

SuperPathways for C10orf35 Gene

No Data Available

Interacting Proteins for C10orf35 Gene

Gene Ontology (GO) - Biological Process for C10orf35 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C10orf35 Gene

Drugs & Compounds for C10orf35 Gene

No Compound Related Data Available

Transcripts for C10orf35 Gene

mRNA/cDNA for C10orf35 Gene

Unigene Clusters for C10orf35 Gene

Chromosome 10 open reading frame 35:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C10orf35

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C10orf35 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1: - -
SP2:
SP3: -
SP4: - -

Relevant External Links for C10orf35 Gene

GeneLoc Exon Structure for
C10orf35
ECgene alternative splicing isoforms for
C10orf35

Expression for C10orf35 Gene

mRNA expression in normal human tissues for C10orf35 Gene

mRNA differential expression in normal tissues according to GTEx for C10orf35 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x5.3) and Brain - Cerebellum (x4.6).

Protein differential expression in normal tissues from HIPED for C10orf35 Gene

This gene is overexpressed in Bone (41.3), Fetal Brain (8.5), and Frontal cortex (7.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for C10orf35 Gene



SOURCE GeneReport for Unigene cluster for C10orf35 Gene Hs.522992

genes like me logo Genes that share expression patterns with C10orf35: view

Protein tissue co-expression partners for C10orf35 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C10orf35 Gene

Orthologs for C10orf35 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C10orf35 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C28H10orf35 35
  • 89.44 (n)
  • 95 (a)
C28H10ORF35 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C4H10orf35 35
  • 90 (n)
  • 92.5 (a)
C10orf35 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2010107G23Rik 35
  • 85.56 (n)
  • 93.33 (a)
2010107G23Rik 16
2010107G23Rik 36
  • 93 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf35 35
  • 99.17 (n)
  • 100 (a)
C10orf35 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1305587 35
  • 85.28 (n)
  • 93.33 (a)
oppossum
(Monodelphis domestica)
Mammalia C10orf35 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C10orf35 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C10orf35 36
  • 66 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c10orf35 35
  • 64.1 (n)
  • 63.25 (a)
Str.16059 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.7113 35
Species with no ortholog for C10orf35:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C10orf35 Gene

ENSEMBL:
Gene Tree for C10orf35 (if available)
TreeFam:
Gene Tree for C10orf35 (if available)

Paralogs for C10orf35 Gene

No data available for Paralogs for C10orf35 Gene

Variants for C10orf35 Gene

Sequence variations from dbSNP and Humsavar for C10orf35 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs12020 -- 69,632,801(-) CCCCT(A/G)TTGAA reference, synonymous-codon
rs899022 -- 69,633,740(-) CTGCG(A/T)TCCTA downstream-variant-500B
rs977096 -- 69,630,637(-) TGACA(C/T)GTATG intron-variant, reference, missense, upstream-variant-2KB
rs1052152 -- 69,632,936(+) CATCT(C/T)GGCAA synonymous-codon, reference
rs1052164 -- 69,633,372(+) AAGAT(C/T)TCAGC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for C10orf35 Gene

Variant ID Type Subtype PubMed ID
esv32737 CNV Gain+Loss 17666407
nsv7032 CNV Insertion 18451855
nsv509356 CNV Insertion 20534489

Variation tolerance for C10orf35 Gene

Residual Variation Intolerance Score: 65.41% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.53; 11.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C10orf35 Gene

HapMap Linkage Disequilibrium report
C10orf35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C10orf35 Gene

Disorders for C10orf35 Gene

MalaCards: The human disease database

(1) MalaCards diseases for C10orf35 Gene - From: DISEASES

Disorder Aliases PubMed IDs
uterine benign neoplasm
- elite association

Relevant External Links for C10orf35

Genetic Association Database (GAD)
C10orf35
Human Genome Epidemiology (HuGE) Navigator
C10orf35
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C10orf35
genes like me logo Genes that share disorders with C10orf35: view

No data available for UniProtKB/Swiss-Prot and Genatlas for C10orf35 Gene

Publications for C10orf35 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. (PMID: 24509480) . … Morris A.P. (Nat. Genet. 2014) 67
  5. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PMID: 22005930) Hollingworth P. … Williams J. (Mol. Psychiatry 2012) 67

Products for C10orf35 Gene

Sources for C10orf35 Gene

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