C10orf32 Gene
protein-coding GIFtS: 36
GCID: GC10P104613
|
|
chromosome 10 open reading frame 32
| |
Aliases
for C10orf32 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 10 Open Reading Frame 321 2 | | FLJ407521 | | RP11-753C18.62 | | UPF0693 Protein C10orf322 |
Export aliases for C10orf32 gene to outside databasesPrevious GC identifers: GC10P104278 GC10P104604 GC10P104608 GC10P098248 |
Summaries
for C10orf32 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C10orf32 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C10orf32 gene promoter:
E2F-4 E2F-3a GR E2F-5 C/EBPbeta E2F-2 E2F-1 E2F c-Myb GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for C10orf32
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf32 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q24.32 Ensembl cytogenetic band: 10q24.32 HGNC cytogenetic band: 10q24.33C10orf32 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P104613: view genomic region
(about GC identifiers)
Start:
|
104,613,967 bp from pter |
End:
|
104,632,990 bp from pter |
Size:
|
19,024 bases |
Orientation:
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plus strand |
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Proteins
for C10orf32 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CJ032_HUMAN, Q96B45 (See
protein sequence)Recommended Name: UPF0693 protein C10orf32 Size: 105 amino acids; 11564 Da
Secondary accessions: B2R488 B3KUW4 C9K0X3Explore the universe of human proteins at neXtProt for C10orf32: NX_Q96B45
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96B45
C10orf32 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001129672.1 NP_653192.2
ENSEMBL proteins: ENSP00000342331 ENSP00000358899 ENSP00000299353
Human Recombinant Protein Products:
C10orf32 Antibody Products:
Assay Products for C10orf32: |
Protein
Domains /
Families
for C10orf32 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96B45 UniProtKB/Swiss-Prot: CJ032_HUMAN, Q96B45Similarity: Belongs to the UPF0693 family |
Function
for C10orf32 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): C10orf32 (NM_144591) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf32 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf32 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf32 |
|
Pathways & Interactions
for C10orf32 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C10orf32
|
Drugs & Compounds
for C10orf32 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C10orf32
Search CenterWatch for drugs/clinical trials and news about C10orf32 / CJ032
|
Transcripts
for C10orf32 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C10orf32 gene (2 alternative transcripts): NM_001136200.1 NM_144591.3 Unigene Cluster for C10orf32: Chromosome 10 open reading frame 32 Hs.34492 [show with all ESTs]Unigene Representative Sequence: NM_0011362004 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000339834(uc001kwh.2 uc001kwi.2) ENST00000369883 ENST00000299353
ENST00000478833
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): C10orf32 (NM_144591) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C10orf32 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf32 |
Additional cDNA sequence: AK098071.1 AK311742.1 AL832477.1 BC015994.1 12 DOTS entries: DT.100024990 DT.100767598 DT.121280233 DT.311522 DT.100767595 DT.91728422 DT.102831805 DT.121280213 DT.95093491 DT.100781355 DT.107073 DT.75102658 24/261 AceView cDNA sequences (see all 261): AI675080 W04252 BF196047 CA444341 AI652047 BE907345 AA976545 AW157005 AA992126 AI868325 BX279728 BQ028789 BQ708132 BF056533 AV650805 AV762757 AW015806 CA312126 N42402 AV650273 BQ186811 AW301647 CA777536 AK098071
GeneLoc Exon Structure
|
Expression
for C10orf32 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C10orf32 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTCTGTTGT
About this image
See C10orf32 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C10orf32
SOURCE GeneReport for Unigene cluster: Hs.34492
SABiosciences Custom PCR Arrays for C10orf32
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf32
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C10orf32 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf32 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf32 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf32 |
Orthologs
for C10orf32 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for C10orf32 gene from 5/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
2010012O05Rik1 , 5 |
RIKEN cDNA 2010012O05 gene1, 5 |
90.16(n)1
96.19(a)1 |
|
19 (38.97 cM)5
664391 NM_025563.31 NP_079839.11
466899065 |
chicken
(Gallus gallus) |
Aves |
C6H10orf321 |
chromosome 6 open reading frame, human C10orf32 |
79.56(n)
88.68(a) |
|
423869 XM_421734.3 XP_421734.2 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.21872 |
Transcribed sequence with moderate similarity to protein more |
79.07(n) |
|
AL848799.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.160362 |
Transcribed sequence with moderate similarity to protein more |
80(n) |
|
CB361857.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG180656 |
-- |
27(a) |
1 ↔ 1 |
2R(16437838-16439591) |
ENSEMBL Gene Tree for C10orf32 (if available)
TreeFam Gene Tree for C10orf32 (if available) |
Paralogs
for C10orf32 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C10orf32 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C10orf32 (104613967 - 104632990 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C10orf32: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf32 |
|
Disorders
/ Diseases
for C10orf32 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C10orf32 for disorders About GeneDecksing
1  disease for C10orf32: About MalaCardsparkinson's disease
Export disorders for C10orf32 gene to outside databases
|
Publications
for C10orf32 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C10orf32 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with C10orf32) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Genome-wide association study reveals genetic risk un derlying Parkinson's disease. (PubMed id 19915575)1 SimA^n-SA!nchez J....Gasser T. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for C10orf32 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C10orf32 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C10orf32 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C10orf32 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C10orf32 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C10orf32 gene:
Search GeneIP for patents involving C10orf32
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C10orf32 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C10orf32 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C10orf32 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C10orf32 | | | OriGene Protein Over-expression Lysate for C10orf32 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C10orf32 | | OriGene 3'-UTR Clone for C10orf32 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C10orf32 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C10orf32 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C10orf32 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C10orf32 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C10orf32 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C10orf32 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C10orf32 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C10orf32 |
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 | | | C10orf32 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C10orf32 |
|  |  |  | | | | Search ThermoFisher Antibodies for C10orf32 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C10orf32 |
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